Articles Related to Health

A cross sectional survey on socio economic and health status among randomly selected rag pickers in the dump site of Mekelle city was done during 2020. The study showed that all rag pickers were 19 to 25 years old males; 60% of them were educated up to secondary level

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Alan Turing and John McCarthy (1950-1955) coined the concept of artificial intelligence (AI) 70 years ago. Today AI is a reality for some areas of medicine, both human and veterinary, and other technological areas. Materializing into a transformative force within the new human, animal and ecological reality of preservation and sustainable development.

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Rapid data collection can provide an insight into causation, the socio-cultural reality, and complex social processes. This is especially important in disease outbreaks when information is quickly required on local needs that is essential for success. Quantitative data alone are not sufficient to provide an in-depth understanding. The challenge is to use a rapid data collection approach that can provide practical solutions by integrating the available evidence, professional expertise, and stakeholder experiences. This viewpoint reflects the opinions of the author that highlight the strengths and weaknesses of rapid data collection and the presentation of an approach that can be implemented with minimal interference in a health promotion and healthcare program context

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Justificative: This trial was conducted in order to register a new generic product of Rivaroxaban. Objective: To evaluate the bioequivalence of rivaroxaban formulations manufactured by Eurofarma Laboratórios S/A and the reference drug, Xarelto (Bayer) under fasting and fed conditions. Methods: Three randomized, open label, balanced, 2 treatments, 4 periods, 2 sequences, single dose, full replicate, crossover studies in 48 healthy adult human subjects under fed and fasting conditions for rivaroxaban 10 mg and 20 mg. Rivaroxaban concentrations in plasma were determined using a validated HPLC-MS/MS method.

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The study aimed to assess the attitudes toward dental and oral health of parents of children receiving anti-cancer treatment. Methods: This cross-sectional descriptive study was based on a convenience sample of parents of 50 pediatric patients who were receiving anti-cancer treatment (study group) and 62 parents of healthy children (control group). Questionnaires were distributed to assess awareness towards oral and dental care.

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The demand for pesticides has increased in today's world of expanding population in order to boost crop productivity and eliminate undesirable plants (weeds) that grow alongside the primary crop.

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Background: The smell in a hospital is an amalgam of smells, emanating from varied sources. But primarily the smell is from the strong cleaning agents used in corridors, including phenyl and bleaching powder, etc. Chemicals that trigger odors may cause health effects. A strong urine odor is also responsible for foul smells in hospitals and other public facilities. Strong odors may cause some people to feel a burning sensation, leading to coughing, wheezing, or other breathing problems.

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Objective: The purpose of this study was to compare the bioavalability between the two 80 mg Valsartan Tablets formulations and to evaluate the bioequivalence of Reference and Test formulations of Valsartan Tablets 80 mg in Healthy adult chinese Male and Female subjects under Fasting and Fed condition.

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Background and Purpose: Escherichia coli (E. coli) is one of the multidrug-resistant pathogens, producing extendedspectrum beta-lactamase enzymes. Molecular typing of this pathogen can be useful for determining the source of dissemination and transfer of resistance and virulence genes of these isolates. Considering the significance of infection in children, in this study, we examined the stool flora of children (<10 years) to show the characteristics and clonal relationship of the isolates.

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During the last three decades innovation in technology and medical care across borders had led to the current understanding that exponential adopting of new technologies in low- or middle-income countries can improve, if not solve, long standing health humanitarian problems.

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Low levels of psychological wellbeing pose considerable burdens on society in terms of mortality, unemployment, absenteeism, medications, social services, morbidity, and in-out patients’ costs. Early detection and preventive treatments may help to reduce costs and improve quality of life. Researchers have proposed several measures and tried to identify new measures of psychological wellbeing, but there is not a universally accepted measure, and all the existing ones have their own limitations. This paper discusses research results focusing on behavioral, psychological, social, demographic features and biomarkers of psychological wellbeing and mental disorders associated with low psychological wellbeing levels. The features which are addressed in the paper are categorized into three groups: affecting features, features for therapy and detecting features. This categorization is described and defended.

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Introduction: Mechanical disorganization of the bacterial biofilm is the cornerstone of the prevention of gingivitis and periodontitis periodontal diseases. The objective of this study was to evaluate the periodontal health of schoolchildren in Widou, Ferlo. Methodology: This was a descriptive, cross-sectional study of schoolchildren living in Widou in the centre of Ferlo. The survey was exhaustive and concerned the only school in the locality. The epidemiological data collected concerned oral hygiene practice, periodontal health and socio-demographic characteristics such as sex, age and educational level. The degree of hygiene was assessed by the Silness and Loe plaque index (Plaque Index); inflammation and bleeding on probing were assessed by the Loe and Silness gingival index (Gingival Index). Results: In a total of 126 schoolchildren, boys and girls were equally represented and the average age was 10 years +/- 2.16.Sixty-nine percent (69%) of the children examined did not use a toothbrush. Of these, more than 47% reported brushing 3 times a day. The plaque index mean value was 1.23 and 99.2% of the population had a moderate plaque control. The average gingival index was 0.96 and 80.2% of the sample had moderate gingival inflammation. Conclusion: The study showed a relatively low rate of toothbrush use in contrast to the tooth stick and a relatively high rate of periodontal index. Communication-based approaches to behaviour change in children are needed to improve periodontal health.

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The objective of this study was to assess which factors, at hierarchical levels, are associated with adequate consumption of fruits and vegetables (FV) in undergraduate and graduate students. This is a cross-sectional analysis of the baseline of the Cohort of Universities of Minas Gerais (CUME Project), with alumni from Universities of Minas Gerais, Brazil, in the years 2016 and 2018. The outcome variable was adequate consumption of FV (≥400 g/day). The exposure variables were divided into: block 1, socioeconomic (marital status, education, professional status, individual and family income); block 2, behavioral (physical activity, alcohol consumption, tobacco use, and consumption of legumes, natural juices, ultra-processed foods, soft drinks and industrialized juices, and fast foods); block 3, individual (gender, age, skin color, self-perception of health and presence of obesity, systemic arterial hypertension, diabetes mellitus, and depression). To verify the associations, hierarchical multiple logistic regression was used. The sample consisted of 4,124 individuals with a median age of 34 years and Interquartile Range (IQ) of 12 years, 68.1% women, with a high frequency (62.2%) of adequate consumption of FV. This adequate consumption of FV was associated with being a woman (OR=1.41; 95%CI 1.21-1.64; p<0.001), advancing in age and being physically active (OR=2.10; 95%CI 1.78-2.47; p<0.001), having regular consumption of natural fruit juice (OR=2.00; 95%CI 1.70-2.34, p<0.001), or consumption of ultra-processed foods (OR=0.96; 95%CI 0.95-0.97; p<0.001). In conclusion, individual and behavioral factors are associated with adequate consumption of FV in highly educated individuals.

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Aim: to demonstrate the PK/PD equivalence of an ovine enoxaparin to the reference product, the originator porcine enoxaparin, Lovenox® from Sanofi, and to assess its safety and tolerability in healthy volunteers with s.c. administration. Methods: a randomized, open-label, 2-way cross-over, single-dose study with 7 days wash-out period was conducted in healthy volunteers of both sexes. A single s.c. injection of 6,000 IU ovine enoxaparin from Metiska Farma (the test drug, T) or Lovenox® from Sanofi (the reference drug, R) was given randomly to each subject in fasting condition. The PD endpoints measured were anti-FXa and anti-FIIa activities in plasma, whereas the PD parameters determined for these endpoints were AUEC0-t (area under the effect curve from time 0 to the last measured activity (t)) and Amax (maximum activity). Bioequivalence (BE) is based on anti-FXa activity, the 90% CIs for GMR T/R (geometric means ratio of Test/ Reference) of AUEC0-t and Amax must fall within the BE limits of 80.00 – 125.00%. The anti-FIIa data are in vivo supportive evidence only. Results: a total of 23 healthy volunteers completed this study. The 90% CIs for GMR T/R of AUEC0-t and Amax for anti-FXa were 107.55 – 116.33% and 110.17 – 117.68%, respectively, while those for anti-FIIa were 100.93 – 122.56% and 105.19 – 124.44%, respectively. All parameters fell within the BE criteria of 80.00 – 125.00%. One AE (adverse event) occurred in one volunteer after s.c. injection of ovine enoxaparin, i.e. bruising which disappeared after a few days. Conclusions: the ovine enoxaparin from Metiska Farma was bioequivalent to the reference porcine enoxaparin (Lovenox®) from Sanofi. Both enoxaparin products were shown to have high safety and tolerability after a single dose in healthy volunteers. This is the first study showing BE of a nonporcine enoxaparin to the reference porcine enoxaparin in Indonesia, a Moslem country

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Backgrounds: Neurolathyrism is a disease, which is linked with the consumption of Lathyrus sativus ( L. sativusi) pulse that contain the neurotoxin-beta-N-oxalyl-L-alpha-beta-diamino propionic acid (beta-ODAP). Patients with Lathyrisum suffer with gradual enhancement in spasticity and bony changes, which are responsible for appearing the crippling condition throughout life. Objective: The present study has been done as to establish the present situation of L. sativusi consumption and Lathyrisum. Materials and Methods:We performed the survey in the village of Mohammadabad Block of Gazipur district in Eastern Uttar Pradesh (a state with maximum population in India) which have population of million, and L. sativusi is the main pulse of the year, which sustains the economy of these populations. Results:Out of 21,234 subjects L. sativusi eating population for more than 10 years, none had Lathyrisum. On contrary, to popular belief, this population enjoys various dishes made by L. sativusi pulse which in popular are local delicacy. Conclusions:There is no evidence of L. sativusi causing Lathyrisum in 2021. On contrary, L. sativusi pulses have become an inheriting part of the food habits in these populations.

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