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Articles Related to Identification

Identification of Apposite Antagonists of Pro-Survival Bcl-2 from Morus alba in the Fight against Human Malignancies: An In Silico Approach

The target of most cancer chemotherapeutic agents is to drive cancer cells toward death, necessitating the need to find a fine balance between anti-apoptotic and pro-apoptotic proteins in maintaining cellular homeostasis. Any shift favoring the pro apoptotic proteins is needed to drive cellular death in cancer chemotherapy. Therefore, this study uses molecular docking, ADMET predictions, and molecular dynamics simulations for the identification of potent inhibitors of anti-apoptotic Bcl-2 from Morus alba. Our molecular docking study discovered that quercetin-3-(6- malonylglucoside) (-10.912kcal/mol) and epigallocatechin gallate (-9.750kcal/mol) recorded excellent binding affinity against human Bcl-2, better than popular stan dard drugs, venetoclax (-9.468(kcal/mol) and navitoclax (-9.058kcal/mol). Interactions profile summary clearly showed that hydrophobic interactions at TRP141, VAL145, and TYR105 were consistently maintained by the ligands, and all the com pounds, except venetoclax, consistently maintained the hydrogen bonding at TYR105. MD simulation analysis showed that the protein and ligand RMSD for the quercetin-3-(6-malonylglucoside)-Bcl-2 complex fell within permissible range, suggest ing the ligand is capable of functioning as apposite antagonists of Bcl-2. Epigallocatechin gallate also bind excellently with the target, and both ligands showed favorable ADMET parameters. Summarily, this study identifies two compounds of mul berry as potential drug candidate in the management of known human malignancies, and therefore suggest the compounds should further be assessed through in vitro and in vivo approaches to validate the reports documented here
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Analyzing Power of Eyewear for Individual Identification

Crime scenes offer a wealth of tangible evidence crucial for reconstructing events, identifying suspects, and substantiating or refuting facts. Eyewear fragments, though often overlooked, constitute valuable forensic evidence. Eye power, indicative of the prescription required for corrective lenses, is determined by individual ocular characteristics such as eyeball shape, size, corneal curvature, and lens properties. This study aimed to explore the distinctiveness of eye powers and their potential for predicting biological profiles based on prescription eyewear. Additionally, it sought to examine correlations between eye power, gender, age, and other variables. Data from 100 samples (50 male, 50 female) were collected via an online Google form and analyzed using Microsoft Excel and statistical software. The sample was evenly distributed across age groups (10-34 and 35-59 years), with prevalent blood groups being B+VE and O+VE. Findings revealed higher eyewear usage among participants with both parents wearing glasses and minimal use among siblings. Myopia was more common than hy peropia, and participants reported significant daily screen time, correlating with poorer vision. A notable finding was a strong positive correlation between left and right lens powers, with no significant gender disparities. In conclusion, while eye power effectively distinguishes age groups, its potential for individual identification warrants further refinement and broader application. The study underscored the absence of a centralized database or web tool in India, suggesting the poten tial benefits of developing such resources to enhance forensic accuracy and accessibility. Limitations included a relatively small sample size and the use of non-standardized questionnaires, indicating opportunities for methodological improve ment in future research endeavors
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Denture Barcoding - The Clever Way

Forensic Odontology is the means to identify a person from their dental remains. Various methods are there for identifying an individual. In this study, the main aim is to identify an edentulous person making a positive identification by means of Barcode. A Barcode is a machine-readable code in the form of numbers and a pattern of parallel lines of varying widths, printed on a commodity. The study focuses on creating dentures with identification marks/labels using patient’s identity proofs such as Aadhar Card, PAN card, Voter ID card. And these will be incorporated in the denture after acrylization using cost effective and minimally altering method. This is an attempt to incorporate identity marks in dentures that can be provided by a General Dental Practitioner on day-to-day basis.
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Identification of Novel De-Novo 12q14 -12q22 Gene Mutations and MTHFR C677T Gene Polymorphism Increase Genetic Susceptibility in Hirschsprung Disease - A Rare Case Report

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Isolation of Microorganisms Associated with Palm Oil Contaminated Soil

Aim: Palm oil processing generally generates lots of wastewater (palm oil mill effluent), this is usually discharged into the environment in the untreated form and subsequently causes several environmental issues. There is therefore need to isolate microorganisms that can be used to clean up the palm oil contaminated environment especially the soil. Methods and Results: Palm oil contaminated soil was obtained from Oba Adeyemi palm oil mill in Oyo, Oyo State, Nigeria, other soil samples which were purposely contaminated with palm oil, were obtained from Ajayi Crowther University Oyo, Oyo State. Isolation, characterization and identification of microorganisms were carried out using morphological and biochemical characterization. The isolates were preliminarily screened for lipolytic activities, this was confirmed by growth on the mineral salt medium after 7 days, signifying hydrolysis. One of the prominent isolates was further identified by sequences analysis of 16S rRNA genes. Forty-one bacterial isolates were identified, which included species of Bacillus (80 %), Pseudomonas (20 %) in the oil mill contaminated soil sample and Bacillus spp. (100 %) in the purposely contaminated soils. Twenty-nine fungal isolates including species of Aspergillus, Oidiodendron, Geotrichum, Penicillum, Saccharomyces were isolated with Aspergillus fumigatus having the highest frequency of occurrence (37.5 %) in artificially contaminated soil and Saccharomyces spp. having the highest frequency of occurrence (91 %) in palm oil contaminated soil from the palm oil mill. Sequencing of the 16S rRNA of one of the prominent isolates showed that it was identified as MN607220 Saccharomyces cerevisae. All the bacterial and fungal isolates had lipolytic activities except Bacillus mycoides and Oidiodendron sp. respectively. Nine of the ten Saccharomyces sp. had lipolytic activities. Conclusion: These screened organisms could therefore be employed for the cleanup of palm oil contamination in the environment. Significance and Impact of Study: Thereby ridding the environment of possible toxic effects especially in areas of need like Malaysia
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Public Awareness: Identification of Security Features of Different Bank Cheques

A lot of evidence has been left by the criminals while commencing offenses. Fraud in the banks is easier due to less knowledge of banking documents. Cheques serve to be the most valuable evidence that can provide a lot of crucial information and therefore acts as a forensic tool. Cheques from different banks can be distinguished with the help of certain features present in them such as bank logo, watermarks, design and pattern of cheque, etc. Every cheque was different from each other with respect to the features like position and number of watermarks, fluorescence, voids pattern, micro lettering, size and dimensions of the cheques. Security features are the vital line of defence against cheque fraud.
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Can Bullet Characteristics Link a Bullet to a Manufacturer?

This paper was written to understand if there is a way to identify bullet manufacturer based solely on the shape and characteristics of the bullet. Traditional methods of bullet identification are to use a bullet comparison microscope and look for tool marks and rifling to link it to one particular gun. Cartridge case identification is a lot easier to link to the manufacturer being that there is already some identifying information of the breech face such as the bullet size (9mm), the gun manufacturer (SW-Smith and Wesson), and the trigger pin impression. This research is being done to find an alternative method of bullet identification in the event there are no cartridges left at a crime scene nor does the bullet have sufficient tool marks or rifling to link to a specific gun.
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Antibiotics in Lebanese Surface Waters: Estimation of Population Exposure and Identification of High-Risk Drugs

The evaluation of the environmental risk of antibiotics and their byproducts is an important topic around the world viewing the increase of use of antibiotics and the absence of conventional water treatment plants. The objective of the study is to determine the consumption of antibiotics and evaluate their potential health hazard as contaminants of the Lebanese surface waters. Data of 704 antibiotics consumed in 2019 were provided by the Ministry of Public Health (MOPH).
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Characterization of Pugmark for Animal Species Identification for Forensic Importance

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Optimization of a Conventional PCR Assay for the Identification of Corynebacterium Pseudotuberculosis from Pyogenic Lesions

Caseous lymphadenitis (CL) is a pyogenic disease that is caused by zoonotic bacteria and is in the same family as Corynebacterium diphtheriae (the etiologic agent of human Diphtheria).
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Target Joint “New Concept of Identification”

The hallmark of hemophilia is hemarthrosis. All efforts must be made to early diagnose joint bleeding as soon as it occurs and treat it not later than within 2 h of onset by infusing the appropriate clotting factor. This will prevent the accumulation of blood in the joint as well as inflammation and a potential hemophilic arthropathy. Recurrent bleeding prevents the joint from regaining its range of motion, muscle strength, and normal appearance. These changes become permanent, leading eventually to osteoarthritis. A bleeds joint requires urgent and comprehensive management, especially in young patients, if permanent damage is to be prevented.
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Cattle Ticks and Tick Borne Haemoparasite Species Identification and Associated Risk Factors in Two Districts of West Arsi Zone, Ethiopia

Different tick species and tick-borne diseases of cattle are present in Ethiopia and they induce huge production loss in livestock industry by creating serious animal health problems. The present study was conducted from November 2017 to April 2018 in Arsi Negele and Asasa districts of West Arsi Zone, Oromia National Regional State, Ethiopia. A cross sectional study design and purposive sampling technique were employed to select 384 study animals so as to identify ticks species and tick-haemoparasite species and also to identify risk factors that affect the prevalence and association of tick born diseases. Tick and haemoparasite identification were carried out by using drect stereomicroscopic and direct thin blood examination. The study identified two tick genera and four tick species. The tick species encountered were Rhipicephalus decoloratus (51.6%) Ambylomma variegatum (46.1%) Ambylomma gemma (20.1%) and Rhipicephalus evertsi evertsi (1.2%). Out of all 384 cattle examined for the presence of tick-born haemoparasites 11.4% (n=44) of them were positive. From this 6.2%, 3.6 %, 1.3% and 0.8% of them were positive for Anaplasma marginale, Babesia bigemina, Babesia bovis and Anaplasma marginale, respectively. Two cattle (0.5%) were found positive for both Anaplasma marginale and Babesia bigemina. The highest prevalence of total tick born haemoparasites (57.1%) was occurred in A. Variegatum, A. gemma and R. decoloratus mixed infestations. In conclusion ticks and tick born haemoparasitic infections were common problems in the study area. Thus, awareness creation for farmers about the impacts of ticks and tick born diseases on livestock production and productivity and also applying appropriate and timely strategic tick control methods by veterinary service providers were advisable.
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Photogram - Image Comparison and Identification

A human being is having physical and biological body structure, even though each and every individual is having his own blood group, hair color, retina color, skin complexes, height, breadth etc. that result in his own bodily structure that differentiates with the other individual. After the certain age of subject nearly about twenty years, height or length of his organs or limbs are not increases and fixed bodily structure is built up.
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Wildlife Forensic: Current Techniques and their limitations

The wildlife includes undomesticated and diverse forms of floral and faunal species, which is essential for ecological balance and human survival. The poaching and illegal trade has resulted in sharp decline of many wild species of flora and fauna around the world. The need of the time therefore is to utterly focus on wildlife protection for the sustainable development of biosphere and future viability of human beings. In this review we have focused on different techniques being utilized in wildlife forensic science for identification of wildlife species as well as their geographical origin. These techniques can be employed to control the wildlife crimes and convict the criminals involved in illegal trade of wildlife flora, fauna and their products. These techniques include footprints analyses, morphological and anatomical studies,
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Novel analytical technologies of Quality in the Sheep & Goat Dairy Sector

France, Greece, Italy, and Spain the major sheep and goat milk producers in Europe, got the initiative through an interim of 30 years (1985 – 2015), to organize - through IDF - 7 symposiums aiming at the upgrade of the Dairy Sector. One major interest was the milk quality. Stepwise, the efforts followed cow milk structural development in organizing the testing laboratory, the definition of quality in composition (fat, protein, lactose, total solids), in Hygienic (Total Bacteria Count, Somatic Cell Count, antibiotics residues and Aflatoxin M1 contamination), adulteration with water and detection of milk species. EU, by Decision 2002/657/EC, defined the rules for the Directive 96/23/EC, enumerated the testing methods, the demands in sampling procedures, the minimum limits of performance, the quality control (ISO 17025) and the interpretation of results. The equivalency of results from different laboratories, through ISO 17025, demanded the application of ISO analytical standards.
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Editorial Board Members Related to Identification

Isik Yulug

Associate professor
Department of Molecular Biology and Genetics
Bilkent University
Turkey

Martin Michaelis

Professor
Department of Cell Biology
University of Kent
United Kingdom

Bassam R. Ali

Professor
Department of Pathology
College of Medicine and Health Sciences
UAE University
United Arab Emirates

Yaping Luo

Professor
Department of Forensic Science
China People's Public Security University
China

KEQUAN ZHOU

Associate Professor
Department of Nutrition & Food Science
Wayne State University
United States

JANAK PADIA

Associate Professor
Center of Biomolecular Therapeutics
University of Maryland
United States

HONGWEI HOLLY YIN

Assistant Professor
Cancer and Cell Biology Division
Translational Genomics Research Institute
United States

Rodrigo Fernandez Valdivia

Assistant Professor
Department of Pathology
Wayne State University School of Medicine
United States

Renukaradhya J. Gourapura

Associate Professor
Food Animal Health Research Program,OARDC
The Ohio State University
United States

Cristiana Palmela Pereira

Assistant Professor
Portuguese Institute of Legal Medicine
University of Lisboa
Portugal
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