Articles Related to Oxygen

Infertility is a serious concern affecting millions of couples globally. Natural conception is seen to be achieved in 80-85% couples leading 15 % couples suffer worldwide. Male factor is an important underlying cause associated with infertility. The debate that the ingredients’ of cigarette smoke negatively influence the masculinity attracts the scientific wit to look into the problem.

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Cognitive impairment post TBI is an important factor in rehabilitation outcomes. Pharmacological and therapeutic services do not directly address damage to the cortical infrastructure. Hyperbaric Oxygen Therapy is known to improve brain function and healing.

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Brain physiology critically depends on constant oxygen supply to the neurons to ensure various energy–dependent functions of the central nervous system. A volume of latest experimental data on oxygen metabolism obtained with high temporal and spatial resolution, with both invasive and non-invasive methods, and the use of technologies of various degrees of sophistication, strongly suggests arteriole involvement in brain oxygenation. This new approach challenges the traditional views on brain oxygenation according to which oxygen supply to the brain tissues occurs by diffusion at the capillary level.

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Glucose and oxygen are obligatory energy substrates for the brain and their continuous supply to the neurons, as well as the elimination of the end product – carbon dioxide, is of paramount importance for brain physiology and survival. Transport of these substrates from the brain capillaries to the neurons presents a challenging issue.

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Patients admitted to the emergency room or intensive care units (ICUs) need real-time monitoring of body oxygen balance. As of today, the availability of monitoring devices that provide real-time data on tissue level of oxygen homeostasis is very limited. The involvement of mitochondrial dysfunction in many pathological states such as stroke, sepsis or heart failure is calling for a real-time evaluation of this intracellular organelle. In order to avoid the deterioration of the most vital organs in the body (brain and heart), we are proposing to monitor a less vital organ, such as the urethral wall, that serves as an early warning signal for the deterioration of body oxygen balance.

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Thoracic ultrasonography has been used to evaluate pulmonary parenchyma and the macrocystis of the lung in a preterm with congenital cystic adenomatoid malformation type I. The images gained have been important for diagnosis and therapeutic strategies in our case. An infant was prematurely born with congenital cystic adenomatoid malformation type I. The chest X-ray and computerized tomography showed a great opaque area in the entire right lung, we considered performing a pneumonectomy. This opaque area hampered the expansion of left lung. After draining the macrocystis by ultrasonography-guided puncture, it was possible considering and performing the lobectomy due to the reduction of the volume of macrocystis. During follow up at 4 months, the infant did not show complications and the chest X-ray revealed the reduction of volume of the dense area in parenchyma of right lung.

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Infective Endocarditis (IE) is associated with significant morbidity and mortality, with in-hospital mortality having been reported as ranging from 19-26%. Commonly documented complications of IE include valvular and chordae destruction and resultant regurgitations, embolic events, peri-valvular abscesses, fistulae, and congestive heart failure.

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Accidental hypothermia is a potentially life-threatening situation that involves a debilitated patient and is a result of environmental exposure.

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White adipose tissue (WAT) is an endocrine organ with crucial role in the development of obesity and related diseases. White adipocytes have less mitochondria than brown adipocytes; nevertheless, there is an increasing body of evidence showing that mitochondrial parameters play a relevant role in WAT physiology, such as proliferation, differentiation and triacylglycerol storage levels.

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This paper does not present new experimental data. It is based on existing literature and 40 years of clinical experience as an anesthesiologist. Author believes that it is necessary to look into clinical guidelines for some common, but serious medical conditions

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Mesenchymal stem cells (MSCs) have been found in almost all tissues and due to their regenerative properties represent promising tools in cell-based therapy. Role of MSCs in tissue repair is strongly governed by their interplay with immune cells and regulating factors.

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This paper aims to review in literature the main mechanisms of oxidative stress, pointing out the major formed metabolites, the mechanisms of cell damage and major antioxidants. Oxygen is essential to human life. The formation of free radicals (FR) is closely related to oxygen consumption, a mechanism that occurs with an incomplete reduction of this molecule.

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Eugenol (EU) and ibuprofene (IBU) were covalently bound to a bi-functionalized PEG, used as molecular carrier of drugs and the release kinetics of the two bioactive molecules was studied in vitro in buffer solution at pH 7.4, in simulated gastric fluid and in mouse plasma.

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Titanium dioxide (TiO2) (<100 nm) has been widely used in the production of paints, paper, and plastics, as well as in food additives and colorants .It has been classified as biologically inert in both humans and animals. Here we studied the toxicity of TiO2 on Wister rat. Main exposure area of NPs is caudal vein of Wistar rat.

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In ancient India arrow injury was prevalent as it was a one of the most frequently used weapon. With passage of time use of bow and arrow became restricted to tribal area and its use became limited mostly to hunting. But in the recent years with progressively increasing terrorist activity in some areas arrow injuries are becoming more and more frequent.

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