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Comparative Assessment of De Novo Genome Assemblers for Generating Eukaryotic Primary Genome Assembly from Short Reads

Ameya Santhosh, Rani Alex, Vikas Vohra (2023) Comparative Assessment of De Novo Genome Assemblers for Generating Eukaryotic Primary Genome Assembly from Short Reads. J Comp Sys Bio 6(1): 101
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A Single-Center Experience in Alport Syndrome

Alport Syndrome is a hereditary condition that affects the collagen in the basement membrane and is characterized by microscopic hematuria, sensorineural hearing loss, increasing renal dysfunction, and ocular abnormalities. It is more common between the ages of 20 and 30. Men and women are equally affected. However, the prognosis of men is worse than women due to renal failure. The purpose of this study is to evaluate the demographic and clinical findings of patients with Alport Syndrome in our center
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Accidental Ammonia Gas Leakage in a Cold Storage : A Case Report

: Ammonia is corrosive and exposure will result in a chemical-type burn. It is highly hygroscopic and readily transforms the moist areas of the body such as eyes, nose, throat, and moist skin areas. It is a highly toxic irritant gas, and its toxicity usually occurs from occupational exposure, most are unintentional toxicity. It causes tissue damage via exothermic reaction with body tissues causing liquefactive necrosis. Release of ammonia has potentially for harmful effects on workers and the public. Although there have been incidents of exposure to harmful concentrations of ammonia in the world there have been few fatal accidents.Presentation depends on the level and duration of exposure. Management is supportive and its antidote is not available yet
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Outcomes Following Debridement, Antibiotics, and Implant Retention with the Exchange of Modular Components in Hip Periprosthetic Joint Infections

Shin Onodera, Motomi Ishibe (2023) Outcomes Following Debridement, Antibiotics, and Implant Retention with the Exchange of Modular Components in Hip Periprosthetic Joint Infections. J Orthop Physiother 6(1): 101
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Socio-Economic and Health Status of Rag Pickers in the Dump Site of Mekelle City, Northern Ethiopia

A cross sectional survey on socio economic and health status among randomly selected rag pickers in the dump site of Mekelle city was done during 2020. The study showed that all rag pickers were 19 to 25 years old males; 60% of them were educated up to secondary level
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Smoking and Male Infertility ׃ A comprehensive Review

Infertility is a serious concern affecting millions of couples globally. Natural conception is seen to be achieved in 80-85% couples leading 15 % couples suffer worldwide. Male factor is an important underlying cause associated with infertility. The debate that the ingredients’ of cigarette smoke negatively influence the masculinity attracts the scientific wit to look into the problem.
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Antibodies Anti-Proteins of Larrea Divaricata Cav. Present Opsonic Capacity on Candida Albicans Atcc 36801 and Neutralize its Cytotoxic and Immunoevasive Properties

Candida albicans is an opportunistic agent that can produce systemic infections in immunosuppressed patients. By varying its cell wall antigens this fungus can evade the immunological response by varying its cell wall antigens. On the other hand, Larrea divaricata Cav. (Jarilla) is a widely spread plant in America and it is used in folk medicine to treat several pathologies. It has been shown that antibodies against Jarilla proteins of crude extract (JPCE) cross-react with proteins of other microorganisms such as Gram-negative bacteria.
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Spinal Muscular Atrophy-Type1, Unraveling the tapestry from highly inbred region of North India

spinal muscular atrophy is an autosomal recessive disorder characterized by degeneration of alpha motor in anterior horn cells of brain and spinal cord, which results in muscular atrophy, hypotonia, fasciculations, areflexia, paralysis and even death in most severe cases. The underlying cause of this disease is biallelic loss of survival motor neuron 1 (SMN1) gene. Depending upon the clinical features & patient's age, SMA is classified into different distinctive sub types
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Comparison of Physicochemical and Binding Properties of Novicel™ Microcrystalline Cellulose and Avicel® PH 101 in Direct Compression of Ascorbic Acid Tablets

Microcrystalline cellulose (MCC) is a key excipient in formulation and production of pharmaceutical solid dosage forms such as tablets. In this study, the microcrystalline cellulose (Novicel™) obtained from sugarcane bagasse (a waste material from sugarcane factories) was compared with Avicel PH 101 (a commercially available MCC) for its physicochemical characteristics and potential as a dry binder in direct compression of ascorbic acid tablets.
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Perspectives of Artificial Intelligence in Veterinary Medicine of Small Species

Alan Turing and John McCarthy (1950-1955) coined the concept of artificial intelligence (AI) 70 years ago. Today AI is a reality for some areas of medicine, both human and veterinary, and other technological areas. Materializing into a transformative force within the new human, animal and ecological reality of preservation and sustainable development.
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Radiographic Outcomes of FDBA Block Graft for Maxillary Ridge Augmentation: A Case Report

The primary donor sites for collecting bone in the oral cavity to replace missing ridges are the mandibular symphysis or ramus. Although successful, these bone transplants can nevertheless raise a number of issues, including donor site morbidity, nerve paresthesia, the devitalization of native teeth, and postoperative sequelae . Allogeneic block grafts were developed to address these concerns and a lack of autogenous intraoral bone available for grafting
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Case Report: Pyoderma Gangrenosum in IBD Treated with Tofacitinib

Pyoderma gangrenosum is a rare ulcerating skin disease often presenting as an extra intestinal manifestation of IBD and is difficult to manage. Treatment options for pyoderma gangrenosum include steroids, calcineurin inhibitors and anti TNF agents. Here in, we report a case of recurrent Pyoderma gangrenosum with Ulcerative Colitis that was successfully managed with Tofacintib, a JAK inhibitor
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Leukocytoclastic Vasculitis after Ceftriaxone Exposure: A Case Report and Literature Revie

Leukocytoclastic Vasculitis (LCV) characterizes various small vessel vasculitis types primarily affecting the skin, with occasional internal organ involvement. This inflammation involves immune-complex deposition within dermal capillaries and venues. Although idiopathic in origin, potential triggers, including antibiotic-related factors, must be considered. LCV presents across a spectrum of severity, sometimes extending to ulcers. Diagnosis involves clinical assessment, history, lab tests, and crucially, skin biopsy.
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A Case Report of Rapidly Progressing Amyotrophic Lateral Sclerosis in 31 Year Old Patient with Sympathovagal Imbalance

ALS is a fatal neurodegenerative condition characterized by degeneration of upper and lower motor neuron in cerebral cortex, cranial nerve nuclei and anterior horn cells of spinal cord. Three drugs are FDA approved, Riluzole, Edaravone and AMX0035 (recently approved), which can only prolong survival time by 2-3 months.
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Dento-Supported Impressions in Fixed Prosthesis: Study by Cap Survey of Burkinabe Dental Surgeons

The impression is a key stage in the success of the prosthetic process. Taking an impression remains the most difficult and delicate phase in the prosthetic chain. The aim of this study was to assess the attitude and knowledge of dental surgeons regarding impression taking in dental practices in Burkina Faso.
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Anodic Porous Alumina Array for Cyanine Fluorophore Cy3 Confinement

Self-organized anodic porous alumina films with hexagonal pore lattice have attracted a considerable attention for biological arrays and confinement of various organic probes dyes in solutions. A molecular structure with axial symmetry in bis-heterocyclic indole chains and conjugate system, such as cyanine fluorophore Cy3 dye, was investigated here with respect to its fluorescence when loaded in the anodic alumina pores.
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Anodizing for Design and Function

Two basic reactions occur during the anodizing of aluminum: 1) the aluminum is consumed and 2) an oxide grows. By accepting this statement as true, the anodizing process can be viewed as a corrosion process, and anodizing can be modeled using the Tafel Equation. Anodizing process parameters of electrolyte chemistry and concentration, temperature, aluminum substrate resistance and current density are presented as they relate to the Tafel Equation and how they impact the anodic aluminum oxide structure and properties. Understanding this relationship is consequent in making anodizing an engineering process, one that enables tuning the structure such that it yields distinct characteristics to fulfill design and application requirements.
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Recent Developments in Human Odor Detection Technologies

Human odor detection technologies have drawn attention due to the wide possibility of potential applications they open up in areas such as biometrics, criminal investigation and forensics, search for survivors under rubble, and security checkpoint screening. Gas chromatography/mass spectrometry (GC/MS) has been the most successful and powerful analytical approach developed to date for human odor analysis, and hundreds of human odorants have been identified using this tool.
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Electronic-nose Applications in Forensic Science and for Analysis of Volatile Biomarkers in the Human Breath

The application of electronic-nose (E-nose) technologies in forensic science is a recent new development following a long history of progress in the development of diverse applications in the related biomedical and pharmaceutical fields. Data from forensic analyses must satisfy the needs and requirements of both the scientific and legal communities. The type of data collected from electronic-nose devices provides a means of identifying specific types of information about the chemical nature of evidentiary objects and samples under investigation using aroma signature profiles of complex gaseous mixtures containing volatile organic compounds (VOCs) released from manufactured products and parts of the human body. E-nose analyses also provide useful qualitative information about the physicochemical characteristics and metabolic conditions of human subjects without the need for time-consuming analyses to identify all chemical components in human-derived volatile mixtures.
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Analysis of Sweat Simulant Mixtures using Multiplexed Arrays of DNA-Carbon Nanotube Vapor Sensors

Carbon nanotube (NT) based electronic vapor sensors were tested against synthetic sweat solutions, consisting of 13 volatile organic compounds (VOCs) in saline, in order to probe the device ability to analyze and differentiate vapors derived from complex biological samples.
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Characteristic Human Scent Compounds Trapped on Natural and Synthetic Fabrics as analyzed by SPME-GC/MS

The collection of human odor volatiles is of interest to forensic applications as a path to investigate canine scent discriminations in legal investigations. A study using a selected array of previously identified human odor compounds has been conducted to determine the retention and release capabilities of five (5) natural and synthetic fabric types, cotton (mercerized fabric and gauze matrix), polyester, rayon and wool.
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The Effects of the Film Thickness and Roughness in the Anodization Process of Very Thin Aluminum Films

The anodization of aluminum foils having micrometer thickness is a common process and results in hexagonally self-ordered alumina membranes. However, anodic aluminum oxide (AAO) membranes fabricated from nanometer-thin films present new challenges to the anodization process, since aluminum films adheres poorly on supporting substrates and the smoothness of the film is highly related to the kind of substrate.
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Anodic Oxidation of Titanium in Sulphuric Acid and Phosphoric Acid Electrolytes

Anodisation of pure titanium has been carried out in sulphuric and in phosphoric acid solutions at potentials ranging from 50 to 150V. The SEM and AFM morphological analysis indicates that, within this potential range, oxidation in sulphuric acid solution produces better developed mesoporous oxide layers.
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Fabrication of Ordered Arrays of Anodic Aluminum Oxide Pores with Interpore Distance Smaller than the Pitch of Nano-pits formed by Ion Beam Etching

We investigated a method for preparation of ordered nanopore arrays with the interpore distance of 60 nm by guided self-organization of anodic aluminum oxide with a prepatterned array of pits in the starting Al film.
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Preparation of Large Area Anodic Alumina Membranes and their Application to Thin Film Fuel Cell

The design of an electrochemical reactor for the preparation of self-supported comparatively thin (up to 10 μm) and large area (up to 50 cm2) anodic alumina membranes is described allowing growth of porous alumina at high applied potential (up to 150 V) without burning.
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Fabrication of Vertical Cu2ZnSnS4 Nanowire Arrays by Two-Step Electroplating Method into Anodic Aluminum Oxide Template

Vertical Cu2ZnSnS4 (CZTS) nanowire arrays have been synthesized via two-step electroplating method into anodized aluminum oxide template. For deposition of CZTS nanowires, anodized aluminum oxide (AAO) was used as the growth mask for the growth of the nanowires. AAO templates with hole sizes of 70 nm in diameter were used in the experiments.
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Fabrication and Luminescence of Anodic Alumina with Incorporated Vanadyl Citrate Chelate Anions

Anodic aluminum oxide doped with vanadyl citrate chelate complex anions was formed by a two-step self-organized anodization in 2 wt. % sulfuric acid containing 0.04 M V2O5 and 0.08 M citric acid at voltage range 13-23 V, and at 0 and 15 oC. The combination of two temperatures and at least four voltages (depending on the applied temperature) was applied as the operating conditions of anodization.
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Synthesis of BaTiO3 Nanowires via Anodic Aluminum Oxide Template Method Assisted by Vacuum-and-Drop Loading

In this paper, we report on the synthesis of BaTiO3 nanowires via the anodic aluminum oxide template method. To fill in the precursors of BaTiO3 into anodic aluminum oxide templates, the vacuum and drop loading method developed in our previous study was used. Ba(CH3COO)2 (barium acetate) and C12H28O4Ti (tetraisopropyl orthotitanate) were used as Ba and Ti sources, respectively. Anodic aluminum oxide membranes with the through-hole diameter of ~200 nm were used as the template for BaTiO3 nanowires.
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Editorial Board Members Related to RT

Magdolna Csavas

Associate Professor
Department of Pharmaceutical Chemistry, Faculty of Pharmacy
University of Debrecen
Hungary

Guo-Zhang Zhu

Professor
Department of Biological Sciences
Marshall University
United States

Sheila Barrett

Assistant Professor
Department of Nutrition
Northern Illinois University
United States

Robert H. Rosenwasser

Professor
Department of Neurological Surgery
Thomas Jefferson University
United States

Marcelo L. Rodriguez-Puebla

Associate Professor
Department of Molecular Biomedical Sciences
North Carolina State University
United States

Jui-Ting Hsu

Professor
School of Dentistry
China Medical University
Taiwan

Dayong Wu

Associate Professor
Friedman School of Nutrition Science and Policy
Tufts University
United States

Jaime Morales-Arias

Associate Professor
Department of Pediatrics
Louisiana State University Health Sciences Center
United States

Shehab M. Abd El-Kader

Professor
Faculty of Physical Therapy
Cairo University
Egypt

Mehmet SARIER

Assistant professor
Department of Urology
Altinbaş University
Medical Park Hospital
Turkey
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