Articles Related to SBE
In this study, mature sweet orange fruits (amber variety) were separately subjected to hot water treatments: 35 o C for 25 and 30 minutes; 45 o C for 15, 20 and 25 minutes; 48 o C for 10, 15 and 20 minutes; 50 o C for 10, 15 and 20 minutes; 53 o C for 10 minutes and 55 o C for 5 minutes and were thereafter assessed for their DNA quality while unheated fruits served as control. The DNA quality was done by rapid random polymorphic DNA-polymersae chain reaction (RAPD-PCR) on the extracted DNA from each set of treated fruits using the RAPD primer OPR 02 (5’ – CAC AGC TGC C-3’).
Reduction of Bitterness and Enhancing Palatability of Cetirizine Oral Liquid Dosage Forms by Cyclodextrins
The aim of this manuscript is to study cyclodextrins (CDs) as a potential excipient to suppress bitterness and enhance palatability of pediatric liquid preparations for Cetirizine, an extremely bitter drug. Natural α, β and γ CDs; and β CD derivatives such as hydroxyl propyl (HP), randomly methylated (RM) and sulfobutyl ether (SBE) β-CDs were screened in different molar ratios of 1:1, 1:2 and 1:3 for their inhibition of the extremely bitter taste of Cetirizine using the human gustatory sensation test.