Articles Related to SNP
CCR5 Promoter SNP Genotype in HIV Seropositive Infants on Combination Antiretroviral Therapy in Uganda: Association with Virological Failure
According to the UNAIDS 2022 report, 52% of the HIV positive children between 0-14 years were able to access treatment and of these 68% attain viral suppression. CCR5 promoter genotype specifically single nucleotide polymorphisms have been linked to modulate patient virological status. However, the few studies that have studied the association in infants have utilized allele-specific PCR a genotypic method limited to detecting already known SNPs. By using Sanger sequencing, we explored the association taking into account novel mutations.
Chromosomal Aberrations and HMGA2 Expression in Paroxysmal Nocturnal Hemoglobinuria
Somatic, inactivating PIGA mutations in haematopoietic stem cells, followed by an unknown autoimmune selection process in favor of
the mutated clone, are thought to be important events in the pathogenesis of paroxysmal nocturnal hemoglobinuria (PNH). Recently,
a second clonal event involving the HMGA2 gene was reported in some PNH cases, and over expression of this gene was postulated to
promote proliferation of the mutated clone.
Osteomyelitis of the Hip secondary to Aspergillus fumigatus - A Case Report and Comprehensive Review of the Literature
Aspergillus infection in an immunocompetent human host is a rare entity. In most cases it presents as an opportunistic pathogen in immunocompromised patients. The portal of entry is usually the respiratory tract or direct inoculation of the organism to the site. Aspergillus osteomyelitis is a debilitating and severe form of Invasive Aspergillosis.
Molecular Mechanisms of Mismatch Repair Genes in Cancer – A Brief Review
The DNA mismatch repair (MMR) system is necessary for the maintenance of genomic stability. The MMR system promotes genomic
fidelity by repairing base-base mismatches, insertion-deletion loops (IDLs) and heterologies generated during DNA replication and recombination.
Editorial Board Members Related to SNP
Seyed Fakhreddin
Department of Seafood Processing
Faculty of Marine Sciences
Tarbiat Modares University
Iran
Faculty of Marine Sciences
Tarbiat Modares University
Iran
Fuu –Jen Tsai
Professor
Department of Medical Genetics
School of Chinese Medicine
China
Department of Medical Genetics
School of Chinese Medicine
China
Davit Melkumyan
Head of Arson and Explosives expertises
Department of the National Bureau of Expertises
National Academy of Sciences(NAS)
Armenia
Department of the National Bureau of Expertises
National Academy of Sciences(NAS)
Armenia