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Immunity to Anaplasma marginale and Recent Advances in Vaccine Development

Anaplasma marginale is the etiological agent of bovine anaplasmosis, one of the most prevalent tick-borne diseases of cattle in tropical and subtropical regions that causes significant economic losses to cattle industry. Cattle that survive infection remain persistently infected for life. Immunity against A. marginale infection seems to require both humoral and cellular mechanisms. Antibodies against A. marginale neutralize bacteria by interacting with Major Surface Proteins (MSPs). For this reason, MSPs are believed to be one of the best candidate antigens for vaccine development. Research carried out in the last few years has helped us to understand the antigenic composition of A. marginale and to develop new potential vaccine formulations. Desirable bovine anaplasmosis vaccine must induce protective immunity as well as prevent infection and transmission
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Formulation and Evaluation of Clindamycin Peel-Off Gel Face Mask against Acne Vulgaris

The main aim of this project is to formulate and evaluate Clindamycin peel-off gel face mask against Acne vulgaris. Peel off gel mask of Clindamycin phosphate was formulated using different excipients like Triethanolamine, Carbopol, Polyvinyl Alcohol, Glycerine, Xanthan gum, and Benzyl alcohol. Formulation of different composition of polymer was formulated and their pH, extrudability, homogeneity, spreadability, viscosity, washability and other parameters like drug content, permeability and drug release were evaluated. The result showed that the concentration of PVA and Carbopol which are the main polymers used in the formulations had effect on the drug content, drug release, permeability, spreadability and other parameters. The peel off mask prepared by using different concentration of these two polymers showed satisfactory result in all the evaluated parameters.
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Theory of Mind Understanding and Socioeconomic Status

The participants underwent assessments across all Theory of Mind (ToM) tasks. All individuals were native speakers, comprising 74 from Iran and 66 from Sweden, aged 6-12, and included those with autism spectrum disorder, Down syndrome, and typical development. We conclude that children’s behavior serves as a scale for social and thought problem assessments, evaluated based on teachers' and parents’ scores.
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Horizontal Natural Product Transfer: The Origin of the Widespread Alkaloidal Contaminations of Herbal Products

Alarmed by numerous worrying reports by the European Food Safety Authority related to widespread contaminations of plant-derived commodities by poisonous alkaloids (nicotine, pyrrolizidine alkaloids), the sources of these alkaloidal contaminations were investigated. Our studies revealed that alkaloids, which have been leached out from decomposing alkaloidal donor plants, are taken up by the roots of acceptor plants growing in their vicinity. Based on these results the so-called “Horizontal Natural Product Transfer
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Trends and Day-of-the-Week Effects Decomposition in the Mean and Dispersion in the Number of Subjects Testing Positive for COVID-19 in the UK in 2020

COVID-19 pandemic is a global threat, where the rate of infection with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) increases exponentially, and the spread of the virus from person to person is very fast. Fitting models for COVID-19 counts receive a great attention, and modelling the dispersion of COVID-19 counts helps measuring the spread of the disease in a population and evaluating the intervention
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A Single-Center Experience in Alport Syndrome

Alport Syndrome is a hereditary condition that affects the collagen in the basement membrane and is characterized by microscopic hematuria, sensorineural hearing loss, increasing renal dysfunction, and ocular abnormalities. It is more common between the ages of 20 and 30. Men and women are equally affected. However, the prognosis of men is worse than women due to renal failure. The purpose of this study is to evaluate the demographic and clinical findings of patients with Alport Syndrome in our center
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Which Blood Group is More Anemic: Five Years of Retrospective Experience

The relationship between blood groups and diseases has been a subject of interest for many researchers. This study aims to investigate the susceptibility of each blood group to anemia based on the relationship between the erythrocyte indices and the biochemical parameters used to diagnose anemia.
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Smoking and Male Infertility ׃ A comprehensive Review

Infertility is a serious concern affecting millions of couples globally. Natural conception is seen to be achieved in 80-85% couples leading 15 % couples suffer worldwide. Male factor is an important underlying cause associated with infertility. The debate that the ingredients’ of cigarette smoke negatively influence the masculinity attracts the scientific wit to look into the problem.
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Spinal Muscular Atrophy-Type1, Unraveling the tapestry from highly inbred region of North India

spinal muscular atrophy is an autosomal recessive disorder characterized by degeneration of alpha motor in anterior horn cells of brain and spinal cord, which results in muscular atrophy, hypotonia, fasciculations, areflexia, paralysis and even death in most severe cases. The underlying cause of this disease is biallelic loss of survival motor neuron 1 (SMN1) gene. Depending upon the clinical features & patient's age, SMA is classified into different distinctive sub types
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Temporomandibular Disorders: Assessment of the Knowledge and Current Practices of Senegalese Dentists

Temporomandibular Disorders (TMD) is a generic term encompassing a group of musculoskeletal and neuromuscular disorders. The aim of our study was to assess the evolution of knowledge and current practices of Senegalese dentists regarding temporomandibular disorders, and to measure any disparities in diagnostic and treatment methods.
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Perspectives of Artificial Intelligence in Veterinary Medicine of Small Species

Alan Turing and John McCarthy (1950-1955) coined the concept of artificial intelligence (AI) 70 years ago. Today AI is a reality for some areas of medicine, both human and veterinary, and other technological areas. Materializing into a transformative force within the new human, animal and ecological reality of preservation and sustainable development.
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A Retrospective Study in DUE and ATC/DDD Evaluation of Antibiotics in Specific Departments of a Tertiary Care Hospital

Large numbers of nations are associated with utilization of anti-toxins regardless of remedy (OTC medications). This DDD/ ATC value contributes to improved antibiotic use quality. The principal objective is to direct improvement of sane medication use of strategies and to give a standard technique for information for future evaluation.
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Activated Charcoal and Derivate Materials in Drugs and Biopharmaceutical Purification: Impurity Aspects

In literature are reported various use of activated charcoal AC and derivates in biopharmaceutical purifications.Aim of this work is to verify impurity proficle when using this technology.Various commercial products are reported here but it is not the scope of this work put in relation with any toxicological reaction: only to describe the technique used in this field.Because various drugs and bioproduct need purification steps it is if of interest to see some material science peculiarity
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Study to Find Clinical Characteristics of ABPA in Patients of Severe Bronchial Asthma and Its Relation with Serum Ige Level at Teriary Care Center North India

Allergic bronchopulmonary aspergillosis (ABPA) is an idiopathic inflammatory disease of the lung, characterized by an allergic inflammatory response to colonization of the airways by Aspergillus fumigatus or other fungi. Untreated or inadequatetreatment may lead to poor outcome in patients. Raised level of serum IgE of more than 1000 IU/ML have been considered as one if theimportant diagnostic criteria for ABPA, however relation of serum IgE withs severity ofdiseases is lacking. This study was conducted to find out level of serum IgE in patients ofABPA and to find out corelation of Serum IgE with duration of symptoms and diseasesseverity.
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Immunoprophylaxis against Respiratory Syncytial Virus Infections

Respiratory Syncytial Virus is an etiological cause of lower respiratory tract infections. Due to the controversial therapeutic approach, it has a significant share in the causes of hospitalizations and even fatal outcomes concerning children up to two years of age. The elderly patients, especially the immune compromised and those with co-morbidities, are at a great risk of developing severe conditions because it is often not considered as pathogen. Those are the reasons which determine the necessity of prophylaxis of the abovementioned target groups of patients - children up to two years of age and adults over 65 years of age.
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Introduction to the special issue on ‘Nanostructures by Valve Metal Anodization’

With this special issue of JMSN we are pleased to present significant contributions to a fascinating topic in the field of materials nanostructing, which is the anodization of valve metals. By this treatment porous oxides of controlled geometry can be grown on the respective metal surfaces. To date, aluminum (Al) has been used most often, as confirmed in this special issue where nine out of ten contributions deals with its anodization.
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Recent Developments in Human Odor Detection Technologies

Human odor detection technologies have drawn attention due to the wide possibility of potential applications they open up in areas such as biometrics, criminal investigation and forensics, search for survivors under rubble, and security checkpoint screening. Gas chromatography/mass spectrometry (GC/MS) has been the most successful and powerful analytical approach developed to date for human odor analysis, and hundreds of human odorants have been identified using this tool.
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Electronic-nose Applications in Forensic Science and for Analysis of Volatile Biomarkers in the Human Breath

The application of electronic-nose (E-nose) technologies in forensic science is a recent new development following a long history of progress in the development of diverse applications in the related biomedical and pharmaceutical fields. Data from forensic analyses must satisfy the needs and requirements of both the scientific and legal communities. The type of data collected from electronic-nose devices provides a means of identifying specific types of information about the chemical nature of evidentiary objects and samples under investigation using aroma signature profiles of complex gaseous mixtures containing volatile organic compounds (VOCs) released from manufactured products and parts of the human body. E-nose analyses also provide useful qualitative information about the physicochemical characteristics and metabolic conditions of human subjects without the need for time-consuming analyses to identify all chemical components in human-derived volatile mixtures.
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Characteristic Human Scent Compounds Trapped on Natural and Synthetic Fabrics as analyzed by SPME-GC/MS

The collection of human odor volatiles is of interest to forensic applications as a path to investigate canine scent discriminations in legal investigations. A study using a selected array of previously identified human odor compounds has been conducted to determine the retention and release capabilities of five (5) natural and synthetic fabric types, cotton (mercerized fabric and gauze matrix), polyester, rayon and wool.
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The Effects of the Film Thickness and Roughness in the Anodization Process of Very Thin Aluminum Films

The anodization of aluminum foils having micrometer thickness is a common process and results in hexagonally self-ordered alumina membranes. However, anodic aluminum oxide (AAO) membranes fabricated from nanometer-thin films present new challenges to the anodization process, since aluminum films adheres poorly on supporting substrates and the smoothness of the film is highly related to the kind of substrate.
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Anodic Oxidation of Titanium in Sulphuric Acid and Phosphoric Acid Electrolytes

Anodisation of pure titanium has been carried out in sulphuric and in phosphoric acid solutions at potentials ranging from 50 to 150V. The SEM and AFM morphological analysis indicates that, within this potential range, oxidation in sulphuric acid solution produces better developed mesoporous oxide layers.
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Fabrication of Ordered Arrays of Anodic Aluminum Oxide Pores with Interpore Distance Smaller than the Pitch of Nano-pits formed by Ion Beam Etching

We investigated a method for preparation of ordered nanopore arrays with the interpore distance of 60 nm by guided self-organization of anodic aluminum oxide with a prepatterned array of pits in the starting Al film.
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Preparation of Large Area Anodic Alumina Membranes and their Application to Thin Film Fuel Cell

The design of an electrochemical reactor for the preparation of self-supported comparatively thin (up to 10 μm) and large area (up to 50 cm2) anodic alumina membranes is described allowing growth of porous alumina at high applied potential (up to 150 V) without burning.
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Fabrication and Luminescence of Anodic Alumina with Incorporated Vanadyl Citrate Chelate Anions

Anodic aluminum oxide doped with vanadyl citrate chelate complex anions was formed by a two-step self-organized anodization in 2 wt. % sulfuric acid containing 0.04 M V2O5 and 0.08 M citric acid at voltage range 13-23 V, and at 0 and 15 oC. The combination of two temperatures and at least four voltages (depending on the applied temperature) was applied as the operating conditions of anodization.
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Editorial Board Members Related to SP

Aly Soliman Hamed Derbalah

Professor
Pesticides Chemistry and Toxicology Department
Faculty of Agriculture
Kafr-El-Shiekh University
Egypt

Guo-Fang Zhang

Assistant Professor
Department of Nutrition
Case Western Reserve University
United States

Lia Jiannine

Assistant Professor, Exercise and Sports Science
Department of Health and Human Performance
Nova Southeastern University
USA

Neeta Singh

Associate Professor
Department of Nutrition
University of the Incarnate Word
United States

Faisal Aziz

Postdoc Research Fellow
Hormel Cancer Institute
China & USA

Nagesh Shukla

Infrastructure simulation and modelling team at SMART
University of Wollongong
Australia

Carlo Monaco

Assistant Professor
Department of Biomedical and Neuromotor Sciences
University of Bologna
Italy

SARATH CHANDRA JANGA

Assistant Professor
School of Informatics and Computing
Indiana University
United States

Fabrizio Russo

MD
Department of Orthopaedic and Trauma Surgery
Bio-Medico University
Italy

Nevin Fayez Wanis Zaki

Assistant Professor & Consultant psychiatrist
Faculty of Medicine
Mansoura University
Egypt
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