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Articles Related to Toxicology

Comprehensive Study of Various Chemical Samples in Forensic Toxicology: Focus on Urine Sample

Toxicology deals with the measurement and analysis of toxins. It is itself a vast branch of science, though it has several branches and one of these is forensic toxicology. Forensic toxicology is a branch of toxicology that lines up with other disciplines, namely clinical chemistry, postmortem forensic toxicology, human performance toxicology and forensic drug testing, providing medical jurisprudence of adverse effects such as drug abuse, poisoning and death. The key role of forensic toxicology is to identify and analyse the toxin compounds found during adverse events. This review paper aims to draw an idea about the toxin, in the collected biological chemical samples such as urine samples and their effects on their day-to-day life
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Activated Charcoal and Derivate Materials in Drugs and Biopharmaceutical Purification: Impurity Aspects

In literature are reported various use of activated charcoal AC and derivates in biopharmaceutical purifications.Aim of this work is to verify impurity proficle when using this technology.Various commercial products are reported here but it is not the scope of this work put in relation with any toxicological reaction: only to describe the technique used in this field.Because various drugs and bioproduct need purification steps it is if of interest to see some material science peculiarity
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The Pattern and Outcome of Acute Poisoning at Toxicology Center in St. Peter Specialized Hospital

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New Forensic Protocol in the Era of SARS-CoV-2

During the Sars-CoV-2 pandemic in Italy, even though many people died due to virus-induced complications, there was a warm advice from the government against performing body autopsies, instigating their incineration. It was a reckless decision, leaving clinicians and scientists empty handed when it comes to studying infection-induced tissue changes and subsequent organ failures, making it more difficulties in finding a better clinical solution for combating the virus.
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Copper Oxide Nano-Hydrogel Composite and their Toxicology Studies: A Green Chemistry Approach

The increasing demand for skin care products formulated with metal oxide nanoparticles such as Zinc oxide, Titanium oxide and Copper oxide nanoparticles calls for toxicological safety concerns. Phytochemical assisted synthesis of Copper oxide nanoparticles (CuONPs) has been achieved by a simple, one-pot chemical procedure using polyphenol-rich aqueous extract of Solanum torvum L. as a reducing and capping agent.
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Fatal 2,4-Dinitrophenol (DNP) Ingestion & Use of a Novel Analytical Methodology Testing Post-Mortem Blood Concentrations

2,4-Dinitrophenol (DNP) is readily available online as an unapproved weight loss supplement. Severe systemic toxicity and death have been reported following DNP use.
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The Dose and its Acute Toxicology: A Systematic Review Article in the First Phase of Experimental Pharmacology

Hundreds and thousands of acute toxicity studies are conducted in experimental pharmacology with assumption hypothesis every year. It is usually concluded with inadequately validated data during the period of investigation within 24 hours.
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Impaired Driving Associated with the Synthetic Cannabinoid 5F-ADB

Synthetic marijuana compounds are more potent than ∆9-tetrahydrocannabinol (∆9-THC) and are known to produce a wide variety of clinical symptoms including cardiac toxicity, seizures, and death. Erratic driving by a 45 y/o male was witnessed in the fall of 2017 and roadside evaluation of the driver by the responding law enforcement officer concluded that the driver was intoxicated. Comprehensive analysis of the cigarettes by gas chromatography-mass spectrometry detected the synthetic cannabinoid 5-fluoro-ADB (5F-ADB or 5F-MDMB-PINACA). Validated forensic liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods were used to detect the 5-fluoro ADB metabolite 7 (26.37 ng/mL) in the driver’s blood sample. No other drugs were detected. This case report is one of the first to conclusively show that designer synthetic cannabinoids, commonly referred to as “K2” and “Spice”, can significantly impair driving at relatively low concentrations.
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Fatal road accidents in Spain: psychoactive substances in killed drivers in 2014

Road traffic accidents (RTAs) are often related to impairment by alcohol or drugs. The objectives of this study is to present toxicological data on drivers killed in traffic accidents in Spain in 2014 from a sample of 614 drivers and 240 (out of 614) with positive results for alcohol, illicit drugs and psychoactive medicinal drugs.
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Anti-Inflammatory and Anti-Arthritic Efficacy and Safety of Purified Shilajit in Moderately Arthritic Dogs

The objective of this investigation was to evaluate the efficacy and safety of purified Shilajit in moderately arthritic dogs. Ten client-owned dogs in a randomized double-blinded study received either a placebo or Shilajit (500 mg) twice daily for a period of five months. Dogs were evaluated each month for physical condition (body weight, body temperature, heart rate, and respiration rate) and pain associated with arthritis (overall pain, pain from limb manipulation, and pain after physical exertion).
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Toxicological Screening and Quantitation Using Liquid Chromatography/Time-of-Flight Mass Spectrometry

In recent years, an increasing number of new designer-drugs have increased the demands for general toxicological screening [1]. Limited screening based on immunoassays is commonly used in clinical toxicology, whereas more comprehensive approaches are common in forensic toxicology such as screening based on Gas or Liquid Chromatography (GC or LC) approaches.
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Editorial Board Members Related to Toxicology

MASAYOSHI YAMAGUCHI

Professor
Department of Hematology and Medical Oncology
Emory School of Medicine
Emory University
United States

NIKOLAS P. LEMOS

Professor
Pathology & Laboratory Medicine
University of California
United States

A. Wallace Hayes

Toxicologist
Emory University
United States

Sajjad Pourmozaffar

Assistant professor
Iranian Fisheries Science Research Institute
Iran.

DUARTE NUNO VIEIRA

Professor
Portuguese National Institute of Legal Medicine and Forensic Sciences
University of Coimbra
Portugal

Mohamed Eddouoks

Professor
Faculty of Sciences and Techniques Errachidia
Moulay Ismail University
Morocco

Zhuoxiao Cao

Scientist
Cell biology department
Novo Nordisk China R&D
China

Robert Kinobe

Senior Lecturer
Physiology and Pharmacology
School of Veterinary and Biomedical Sciences
Australia

Richard Simman

Clinical Associate Professor
Department of Surgery
Wright State University Boonshoft School
United States

Abdelwahab Omri

Professor
Department of Chemistry and Biochemistry
Laurentian University
Canada
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