Articles Related to USC

Background and Objective: Septic shock remains an impatient cause of morbidity and mortality. Early restitution of the circulation improve tissue oxygen delivery and increase survival. This study is a prospective randomized single center study its main objective is to investigate the therapeutic value of hypertonic saline in patients with septic shock. Methods: Fifty-two critically ill patients admitted with septic shock divided into two groups, the first group received isotonic saline (control group) starch, while the second received hypertonic saline 5%.

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The aim of controlling/regulating cellular processes by surface patterning of biomaterials is a crucial concept in emerging research fields, where the precise fabrication of micro-nano surface topographies is required at manufacturing scales to meet consumer demand. Photolithography is typically employed for surface patterning; however, the high cost, process complexity, and lack of environmentally friendly and sustainable methodologies represent steep barriers for many researchers. Soft lithographic methods have been utilised extensively as a potential alternative for traditional photolithography, yet a photolithographic step is still required for initial template fabrication. Here, we demonstrate the use of repurposed optical consumer items such as DVDs, diffraction glasses, and gratings that would otherwise be thrown away after their useful lives, being used here as a sustainable approach as templates for the formation of complex nano-patterns. By replicating these templates in polydimethylsiloxane (PDMS) and polylactic acid (PLA), we show the varied interactions of human aortic smooth muscle cells (HAoSMC) to these surfaces. Notably, it was demonstrated that, in comparison to nonpatterned substrates, HAoSMC interaction (adhesion, spreading, and viability) was higher on DVD patterned surfaces compared to diffraction glass and grating patterned surfaces according to the results from cell metabolic activity (MTT and Alamar Blue), and proliferation (total DNA) assays. We demonstrate that a simple, reusable, inexpensive, yet robust technology could be a powerful tool in improving our understanding of cell-surface interactions and for the potential development of medical devices with micro- and nanoscale low or high adhesion features

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spinal muscular atrophy is an autosomal recessive disorder characterized by degeneration of alpha motor in anterior horn cells of brain and spinal cord, which results in muscular atrophy, hypotonia, fasciculations, areflexia, paralysis and even death in most severe cases. The underlying cause of this disease is biallelic loss of survival motor neuron 1 (SMN1) gene. Depending upon the clinical features & patient's age, SMA is classified into different distinctive sub types

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Temporomandibular Disorders (TMD) is a generic term encompassing a group of musculoskeletal and neuromuscular disorders. The aim of our study was to assess the evolution of knowledge and current practices of Senegalese dentists regarding temporomandibular disorders, and to measure any disparities in diagnostic and treatment methods.

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Snoring is a concomitant of sleeping. This phenomenon is not only considered annoying, but also often taboo because it affects the privacy of those affected. In addition, however, snoring can be the cause of sometimes life-threatening diseases, such as hypertension, stroke and myocardial infarction.

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Buschke-Lowenstein tumor or giant condyloma acuminata is a rare disorder of the external genitalia, belonging to the group of verrucous carcinomas, and usually affects immunocompromised men. Human Papillomavirus (HPV) 6 and 11 are potentially involved in the pathophysiology. A detailed questioning, a rigorous clinical examination and complementary imaging are important to establish an accurate lesion assessment and an adapted management. Wide surgical excision is the treatment of choice.

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Previous studies reported that the paraspinal muscles of adolescents with severe idiopathic scoliosis scheduled for surgery contain higher proportion of type Ⅰ fibers on the convex side. However, the muscle properties are unknown in mild adolescent idiopathic scoliosis. The objective of this study was to evaluate the differences among the convex, concave and control sides of the paraspinal muscles in patients with mild AIS and healthy individuals and to help in the treatment of mild AIS patients.

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Cardiac arrest is a leading cause of death in USA, nearly 90% of them fatal and Out of Hospital Cardiac Arrest (OHCA) is a leading cause of death worldwide. The Cardiopulmonary Resuscitation (CPR), especially if administered immediately after cardiac arrest, can double or triple a person’s chance of survival. CPR by training persons increases the frequency the survival rate. Therefore, we aim to look into the common pitfalls that both medical students and genior physicians face in the recognition and dealing Compression in Cardiopulmonary Resuscitation with its outcome.

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Tetanus is caused by Clostridium tetani, which one of its toxins, tetanospasmin is the cause of clinical symptoms. The incubation period is generally 3 days to 3 weeks. The clinical severity is due to the amount of toxin and the neural distance to reach the neuronal body.

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COVID-19 period was characterized by lockdown and quarantine, the aim of this cross-sectional analytical study is to investigate the effect of COVID-19 quarantine on social media use, and its association with musculoskeletal disorders (MSD) among university students.

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It is essential for practitioners to recognize the pathophysiology of commonly presenting infectious diseases and their mode of transmission. This allows healthcare workers to provide a safe perioperative experience for the patient as well as engage in appropriate infection control practices. There are a number of noteworthy pediatric respiratory infections, such as the novel coronavirus, known as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), and pulmonary tuberculosis.

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Sarcopenia is a syndrome which is characterized by the gradual loss of skeletal muscle mass and strength. The progression of sarcopenia can result in adverse outcomes such as physical disability, poor life quality and severe injuries that lead to death.

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Amyloidosis involving the vascular musculoskeletal system is rare and currently, there is no standard treatment protocol for the treatment of skeletal muscle AL amyloidosis associated with vascular myopathies. Furthermore, the data on the efficacy and safety of autologous stem cell transplant is unclear. In this rare case, a biopsy-proven diagnosis of AL type amyloidosis with an unusual presentation of proximal muscle weakness significantly improved with high dose melphalan followed by autologous stem cell transplantation. The patient achieved and maintained remission for a year post-transplant

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Brucellosis is a zoonotic disease that affects a wide range of animals, including domestic livestock, and human. It is considered one of the most common bacterial zoonoses in the world. Endemic in many parts of India little is known about the antibiotic susceptibility or resistance of Brucella isolates from India.

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