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Anti-GnRH Receptor Monoclonal Antibodies, First-In-Class GnRH Analog

A monoclonal antibody (Mab) designated as GHR106 was generated against the extracellular domain (N1-29 synthetic peptide) of human gonadotropin releasing hormone (GnRH) receptor. It is a first-in-class GnRH analog and can serve as a drug candidate for potential applications in the treatment of human cancers and/or fertility regulations.
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A Laparoscopic Assisted Minilaparotomy Hysterectomy approach for Very Large Fibroid Uteri of more than 1000 grams – A Preliminary Study

Minilaparotomy has been used for tubal sterilization for decades. It became a new surgical idea described by some who performed minilaparotomy hysterectomy and achieved outcomes that were less invasive than those of traditional open laparotomy. Pelosi and Pelosi 2004 reported a minilaparotomy procedure in patients in whom vaginal hysterectomy was considered contraindicated. Their procedure offered a safe alternative with minimal access and good outcome.
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