Articles Related to ions
Adherence to Antiretroviral Medication and Factors Affecting it Among HIV-- Positive Patients Receiving it at Adama General Hospital
Before the development of highly active antiretroviral medication, AIDS and related illnesses caused a great deal of suffering and death. All of the AIDS-related morbidities and mortality have considerably decreased thanks to modern medication, especially in industrialized nations. However, this accomplishment is still elusive in underdeveloped nations, particularly in those in sub-Saharan Africa. This failure can be attributed to a number of factors. Poverty, ignorance about the treatment, and inadequate therapy adherence are at the top of this list.
Mathematical Modeling of Pathological Processes in Alzherimer’s Disease
Using kinetic differential equations and the Runge-Kutt algorithm, an analysis of the pathological processes occurring in the course of Alzherimer’s disease was carried out. Thanks to the appropriately selected kinetic equations, the presented model allows to explain the time course of the growth of pathological proteins: beta-amyloid and tau protein and the related loss of nerve cells. The model is based on previous experimental knowledge of Alzherimer’s diseas and is in good agreement with the experimental data.
Bioequivalence Study of Two 80 Mg Valsartan Tablets Formulations in Healthy Chinese Subjects Under Fasting and Fed Condition
Objective: The purpose of this study was to compare the bioavalability between the two 80 mg Valsartan Tablets formulations and to evaluate the bioequivalence of Reference and Test formulations of Valsartan Tablets 80 mg in Healthy adult chinese Male and Female subjects under Fasting and Fed condition.
Simvastatin Manifold Emulsion Preparation and Evaluation: 32 Factorial Design ApproachArticle
Background: Manifold emulsions are used to increase the bioavailability of active medicinal ingredients and to provide a longer drug delivery mechanism. Hydrophobic and hydrophilic combinational surfactants are frequently used to stabilize the manifold emulsions.
Stroke Mimics: Diagnosis and Management of Patients with Suggestive Clinical Manifestations of Ischemic Stroke
Background and Purpose: Ischemic stroke is a treatable medical emergency. The diagnosis of stroke is mainly clinical and not always so obvious. Intravenous thrombolysis treatment with altepase IV and endovascular treatment have been proved as fist-line beneficial options for eligible patients who have acute ischemic stroke. However, approximately 30% of patients who experience an acute neurological deficit compatible with ischemic stroke fall into the category of "stroke mimics"
Multiple intracerebral hemorrhagic lesions complicating minimal cranioencephalic trauma in a child with severe hemophilia A, trisomy 21 and sickle cell trait carrier: a case report
Intracranial hemorrhage (ICH) is a life-threatening complication in hemophilia. It often occurs during childhood after minimal head trauma. It poses a problem of diagnostic and therapeutic management, especially in Africa where CFCs are not always available.
Climate Change: Effects and Adaptation Strategies Among Orange Fleshed Sweet potato (ofsp) Farmers in Anambra East and West Local Government in Anambra State, Nigeria
The study investigated the effects of climate change and adaptation strategies among Orange Fleshed Sweet potato (OFSP)
farmers in Anambra East and West local government in Anambra State, Nigeria. The specific objectives of the study were to
assess the sources of information on climate change by the farmers, determine the causes of climate change in the study
area, ascertain the perceived effects of climate change on OFSP farmers, assess the adaptation strategies used by the farmers
and identify constraints to climate change adaptation strategies.
Chemicals Disinfections and Their Effects on The Dimensional Stability of Alginate: Systematic Review
Dental practice involves a risk of exposure to microorganisms causing many infectious diseases. The risk of contamination starts at the beginning of the prosthetic workflow through impressions. Various chemical disinfection protocols for dental impressions are reported in the literature.
Analysis of Factors Affecting Fertilizer Applications by Yam Farmers in Edo State, Nigeria
The study assessed factors affecting fertilizer applications by yam farmers in Edo State, Nigeria. The specific objectives were to: ascertain the basic source of information among the farmers, determine the factors affecting fertilizer applications on yam production and the constraints working against yam production in the study area. Multistage sampling techniques were used in this study.
The Management of Wetlands in Ghana as a Compliance to the Ramsar Convention
The Government of Ghana recognizes the importance of wetlands as a habitat for wildlife, in the maintenance of the water
table, mitigation of flood conditions, and water purification. Wetlands resources are also known to be of socio-economic
importance and have been harvested for construction poles, fuel-wood, timber for furniture, and craftwork
Machine Learning Prediction of Response towards Anti-VEGF Injections in Patients with DME: Prediction of Post-Injection CST
Diabetic macular edema (DME) has become one of the most potential complications that results in loss of vision in patients with
diabetic retinopathy. Treatment outcomes that have been predicted directly with advent of machine learning (ML) methods after
the initial anti-vascular endothelial growth factor (anti-VEGF) injection, has become extremely vital in the management of DME.
Purpose: The aim of this study is to analyze the efficiency of the ML regression models which were developed and validated to predict the possible post-injection central subfield thickness (CST) value and distant vision best corrected visual acuity (DV BCVA)
in eyes with DME before the anti-VEGF injection is administered at either treatment initiation or during treatment monitoring.
Methods: This retrospective study was conducted in Medical Research Foundation, Chennai, India from January 2010 to
December 2020. The model development emphasized on an ensemble ML system consisting of four ML models that were
developed and trained independently using the clinical parameters to predict the post injection CST value. The dataset
consisting of 906 patients with total of 1874 samples [Optical coherence tomography (OCT) images and clinical parameters] were divided into trained and test set, and the model was validated on test dataset. The predicted CST values was then
compared against the respective sample’s post injection actual CST value. The comparative results were measured in terms
of Correlation Coefficient and Mean Absolute Relative Error (MARE).
Results: On evaluation, we found that Support Vector Regression (SVR) with linear kernel performed best among the
other models with four different scenarios in term of both CST and DVBCVA prediction with correlation coefficient of
0.65, 0.73, 0.75, 0.85 and 0.83, 0.87, 0.89 and 0.92 respectively.
Evaluation of The Viability and Phenotipe of Adipose Derived Cells Harvested Using Different Harvesting and Processing Procedures: A Pilot Study
Abstract
Background: Clinical studies demonstrated the efficacy of therapies based on the autologous grafting of adult mesenchymal stem cells to accelerate the healing and regenerative processes of the skin and mesenchymal tissues therefore, this is
considered a valuable approach in the aesthetic rejuvenation treatment to give volume restoration and skin regeneration
effects.
Objective: The aim of this project consists of the evaluation of the cell viability of adipose tissue (AT) harvested using
the Superficial Enhanced Fluid Fat Injection (SEFFI) procedure standardized by the Authors (AG, FPB). The harvesting
procedure was performed using two different cannulas having 0.8 mm and 1 mm side-port holes, respectively. Cells phenotype and ability to adhere to the plastic surface have been analysed. The results have been compared to those recorded
in adipose tissue harvested using a liposuction system and processed with enzymatic digestion (collagenase).
Methods: This study was performed on adipose tissues harvested from 7 patients (6 females and 1 male) with an average
age of 48.5 years with two different techniques and three different cannulas. We compared the cell vitality of every sample
at T0 and T72. Moreover, the samples were analysed to determine the phenotype: cells were incubated with antibodies
anti human against CD90-FITC, CD73-PeCy7, CD44-PE, CD31-PECy5, CD235a- PECy7, CD34-FITC, CD45-FITC and
CD146-FITC and read using the flow cytometer s3e Cell Sorter, BioRad. Results were analysed using the software Flow Jo.
Association of Viruses with Aplastic Anemia: A Case Control Study
Several viruses are often believed to be associated with acquired aplastic anemia. There is paucity of literature proving the association between viruses and aplastic anemia. We aimed to study the association of aplastic anemia with Human Parvovirus B19 (B19V), Epstein Barr virus (EBV), Cytomegalovirus (CMV), Hepatitis viruses, Measles virus (MV), Varicella Zoster virus (VZV) and Adenovirus (AdV). Between January 2020 to December 2020, confirmed cases of aplastic anemia and age and sex matched controls of iron deficiency anemia were enrolled in the study. They were tested for the above- mentioned viruses for antigen and/or IgM antibody by ELISA and/or nucleic acid by Real Time PCR in serum samples. Relevant history was collected. Cases were followed up at 3, 6 and 12 months after enrollment for recording the outcome. Total 68 cases and 34 controls were included in the study of which 61(89.70%) cases and 12(38.23%) controls were positive for markers of at-least one of the 10 viruses studied. B19V, EBV, CMV and Hepatitis B virus were found to be significantly associated with aplastic anemia. Five patients died within 12 months. Mortality was not associated with viral infections. Viral infections may play a role in pathogenesis of acquired aplastic anemia.
Electronic-nose Applications in Forensic Science and for Analysis of Volatile Biomarkers in the Human Breath
The application of electronic-nose (E-nose) technologies in forensic science is a recent new development following a long history of progress in the development of diverse applications in the related biomedical and pharmaceutical fields. Data from forensic analyses must satisfy the needs and requirements of both the scientific and legal communities. The type of data collected from electronic-nose devices provides a means of identifying specific types of information about the chemical nature of evidentiary objects and samples under investigation using aroma signature profiles of complex gaseous mixtures containing volatile organic compounds (VOCs) released from manufactured products and parts of the human body. E-nose analyses also provide useful qualitative information about the physicochemical characteristics and metabolic conditions of human subjects without the need for time-consuming analyses to identify all chemical components in human-derived volatile mixtures.
Analysis of Sweat Simulant Mixtures using Multiplexed Arrays of DNA-Carbon Nanotube Vapor Sensors
Carbon nanotube (NT) based electronic vapor sensors were tested against synthetic sweat solutions, consisting of 13 volatile organic
compounds (VOCs) in saline, in order to probe the device ability to analyze and differentiate vapors derived from complex biological
samples.
Characteristic Human Scent Compounds Trapped on Natural and Synthetic Fabrics as analyzed by SPME-GC/MS
The collection of human odor volatiles is of interest to forensic applications as a path to investigate canine scent discriminations in
legal investigations. A study using a selected array of previously identified human odor compounds has been conducted to determine
the retention and release capabilities of five (5) natural and synthetic fabric types, cotton (mercerized fabric and gauze matrix),
polyester, rayon and wool.
Fabrication and Luminescence of Anodic Alumina with Incorporated Vanadyl Citrate Chelate Anions
Anodic aluminum oxide doped with vanadyl citrate chelate complex anions was formed by a two-step self-organized anodization in 2 wt. % sulfuric acid containing 0.04 M V2O5 and 0.08 M citric acid at voltage range 13-23 V, and at 0 and 15 oC. The combination of two temperatures and at least four voltages (depending on the applied temperature) was applied as the operating conditions of anodization.
Editorial Board Members Related to ions

Jiang He
Associate Professor
Department of Radiology and Medical Imaging
University of Virginia
United States
Department of Radiology and Medical Imaging
University of Virginia
United States

Nandadulal Bairagi
Associate Professor
Centre for Mathematical Biology and Ecology
Jadavpur University
India
Centre for Mathematical Biology and Ecology
Jadavpur University
India

Mohd Shahbaaz khan
Assistant Consultant Cardiac Surgeon
King Salman Heart Centre
King Fahad Medical City
Riyadh, kindom of Saudi Arabia
Saudi Arabia
King Salman Heart Centre
King Fahad Medical City
Riyadh, kindom of Saudi Arabia
Saudi Arabia

Shi J. Liu
Professor
Department of Pharmaceutical Sciences
University of Arkansas for Medical Sciences
United States
Department of Pharmaceutical Sciences
University of Arkansas for Medical Sciences
United States

Yinggao Zhou
Associate Professor
School of Mathematics and Statistics
Central South University
China
School of Mathematics and Statistics
Central South University
China

Yasemin Bakircioglu Kurtulus
Professor
Chemistry Department
Faculty of Science
Trakya University
Turkey
Chemistry Department
Faculty of Science
Trakya University
Turkey

John V. Planz
Associate Professor
Department of Molecular and Medical Genetics
University of North Texas Health Science Center
United States
Department of Molecular and Medical Genetics
University of North Texas Health Science Center
United States

William J Winslade
Professor
Department of Preventive Medicine and Community Health
The University of Texas Medical Branch
United States
Department of Preventive Medicine and Community Health
The University of Texas Medical Branch
United States

MICHAEL L. GALLOWAY
Associate Professor
Department of Obstetrics and Gynecology
Boonshoft School of Medicine
Wright State University
United States
Department of Obstetrics and Gynecology
Boonshoft School of Medicine
Wright State University
United States