Articles Related to pathophysiology

Pathology of Primary Open-Angle Glaucoma: A Multifactorial Disorder. Review of the Literature

A glaucoma is a group of eye conditions that damage the optic nerve, which is vital to good vision and if not detected early eventually leads to irreversible blindness. Primary open-angle glaucoma the most common type of glaucoma which occurs due to an imbalance of the eye liquid drainage and production. Although, Primary open-angle glaucoma’s optic neuropathic nature which features retinal ganglionic cell loss representing the most prevalent form of glaucoma, its exact a etiology and pathogenesis are unknown.

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Infective Endocarditis at Tricuspid Valve in CHD: What are its Characteristics? What is the Pathophysiology?

Infective endocarditis (IE) is a serious infectious disease that carries a high mortality rate. We report the case of 74-year-old female who is a chronic hemodialysis patient, and was presented with tricuspid valve endocarditis (TVIE) with central venous catheter, due to an Enterobacter Cloacae, which is a non-HACEK Gram-negative bacilli (GNB) and has been reported to be an extremely rare pathogen of IE. The patient was treated with imipenem and teicoplanin for a four-week period, with negative Blood culture and normal C reactive protein (CRP) levels at the end. The aim of our study is to understand the pathophysiology of the IE in chronic renal failure (CRF) especially at the tricuspid valve (TV), and to determine the clinical, biological characteristics and therapeutic modalities.

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Mckittrick-Wheelock Syndrome and Diabetes Insipidus

Secretory villous adenoma is characterized with watery diarrhea, which may lead to dehydration, with resulting volume depletion, electrolyte imbalance, circulatory failure and renal dysfunction. We hereby report a case of villous adenoma associated with severe electrolyte imbalance complicated by diabetes insipidus.

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Understanding the Value of Case Reports and Studies in the Context of Clinical Research, Research Design, and Evidence-Based Practice

Case reports and studies may be defined as the non-experimental description of an individual or a few of cases in terms of new or unusual presentation of the diseases, an unexpected disease course or pathophysiology, and new effects (either beneficial or detrimental) of existing medications or procedures. Although they suffer from the non-experimental nature and other potential bias and errors, case reports and studies have played and will continue to play an important part in the advancement of medicine.

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