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Articles Related to sedation

Reduction of Bitterness and Enhancing Palatability of Cetirizine Oral Liquid Dosage Forms by Cyclodextrins

The aim of this manuscript is to study cyclodextrins (CDs) as a potential excipient to suppress bitterness and enhance palatability of pediatric liquid preparations for Cetirizine, an extremely bitter drug. Natural α, β and γ CDs; and β CD derivatives such as hydroxyl propyl (HP), randomly methylated (RM) and sulfobutyl ether (SBE) β-CDs were screened in different molar ratios of 1:1, 1:2 and 1:3 for their inhibition of the extremely bitter taste of Cetirizine using the human gustatory sensation test.
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Editorial Board Members Related to sedation

Somchai Amornyotin

Professor
Department of Anesthesiology
Mahidol University
Thailand

Clemente Maia S. Fernandes

Professor
Sao Paulo State University
Araraquara, Sau Paulo
Brazil
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