Articles Related to sedation
Reduction of Bitterness and Enhancing Palatability of Cetirizine Oral Liquid Dosage Forms by Cyclodextrins
The aim of this manuscript is to study cyclodextrins (CDs) as a potential excipient to suppress bitterness and enhance palatability of pediatric liquid preparations for Cetirizine, an extremely bitter drug. Natural α, β and γ CDs; and β CD derivatives such as hydroxyl propyl (HP), randomly methylated (RM) and sulfobutyl ether (SBE) β-CDs were screened in different molar ratios of 1:1, 1:2 and 1:3 for their inhibition of the extremely bitter taste of Cetirizine using the human gustatory sensation test.
Editorial Board Members Related to sedation
Clemente Maia S. Fernandes
Professor
Sao Paulo State University
Araraquara, Sau Paulo
Brazil
Sao Paulo State University
Araraquara, Sau Paulo
Brazil
Somchai Amornyotin
Professor
Department of Anesthesiology
Mahidol University
Thailand
Department of Anesthesiology
Mahidol University
Thailand