Articles Related to symptomatic
Surgical Management of Asymptomatic Hyperparathyroidism: Long-Term Follow-Up
Background: Primary hyperparathyroidism (PHPT) is a frequently diagnosed endocrine disease and nowadays it is asymptomatic in the majority of patients. The management of asymptomatic PHPT is still debated in some cases, although
there are evidences that asymptomatic patients may have improved outcomes after curative surgery. In this paper we show
one of the longest follow-ups of surgically treated asymptomatic PHPT, focusing on skeletal long-term effects of surgery.
Methods: We included in the study 21 patients that underwent parathyroidectomy for asymptomatic PHPT at our Institution from 2006 to 2010 with a complete follow-up at 10 years. Data about age, BMI, preoperative serum and urinary
calcium, vitamin D, alkaline phosphatase parathormone, bone densitometry, surgical procedure and histological examination were collected and analyzed.
Results: At follow-up we observed a normalization of PTH, serum calcium and alkaline phosphatase in all patients. Moreover, in all cases the T-score at 1 year increased significantly both at lumbar spine and femoral neck and this is maintained
at long-term follow-up.
Conclusions: Parathyroidectomy can be proposed as a safe therapeutical option in the majority of cases of asymptomatic
PHPT considering the good results of surgery in terms of bone demineralization reduction
Medical Management of Symptomatic Gallstones: A Narrative Review
Fifteen studies, representing over 2,500 patients, have found that up to 40% of patients continue to have abdominal pain
and symptoms after cholecystectomy. As a result, there is increasing interest in non-operative approaches for managing patients with
symptomatic gallstones. The goal of this study was to summarize the existing evidence and identify remaining evidence gaps for the
medical treatment of symptomatic gallstone disease: including synthetic phospholipids, synthetic bile acids, choleretics, cholesterollowering medications, and diet
Role of MRI in the Clinical Exigesis of Asymptomatic Medial Collateral Ligament Injurie
Magnetic resonance imaging (MRI) of medial collateral ligament (MCL) injury of the elbow was often observed in asymptomatic
adolescent basketball players. We aimed to clarify the clinical interpretation of “asymptomatic MCL injury observed on MRI”
by comparing MRI, ultrasonography (US), and physical findings.
Syncope in Chronic Constitutional Hypotension: Gender based Retrospective observational study in symptomatic women
The association between chronic constitutional hypotension (CCH) and symptoms is uncertain both as pathophysiological correlation as a statistical link. The study was undertaken in order to investigate the existence of a significant association between CCH and symptoms and identify the most represented ones.
Schwannoma Palate in Children: Rare Case
Schwannoma is a benign tumor that originates from the presence of Schwann cells of the peripheral nerves. They are usually asymptomatic, do not recur, and malignant transformation is rare.
Acrometastasis from a Pancreatic Primary Adenocarcinoma: A First Report in the Literature
A seventy five year male presented with acute onset right foot pain and swelling. Plain imaging revealed a lytic area in the medial and middle cuneiform bones of the right foot. Background history of resected pancreatic cancer and current presentation were consistent early diffuse disease recurrence of a pancreatic primary tumour. The presenting feature in this case was of symptomatic acrometastases, that is, metastases to the feet.
Juvenile Ossifying Fibroma - WHO Type
Juvenile ossifying fibroma is an uncommon clinical entity, its aggressive local behaviour and high recurrence rate mean that it is important
to make an early diagnosis, apply the appropriate treatment and, especially, follow the patient up over the long term. In the
current article we report a case of juvenile ossifying fibroma-WHO type in 12yr old patient which was clinical and histopathologically
challenging as it was asymptomatic and at an unusual location.
Esophageal Cancer and Bisphosphonates
At the beginning of 2009, Dianne Wysowski of the US Food and Drug Administration summarized 23 reports of esophageal1 cancer following alendronate use. Wysowski also noted that there had been 31 cases following alendronate use in Europe and Japan and ten cases in which other bisphosphonates had been reported as concomitant or suspect treatment.
Salmonella Serovars and Their Host Specificity
Salmonella is a causative agent for a wide variety of pathological diseases in humans, cattle, poultry and other farm animals and hence Salmonella infections are a major cause of concern to humans, veterinary animals and to food industry.
