- Molecular Mechanism Linking BRCA1 Dysfunction to High Grade Serous Epithelial Ovarian Cancers with Peritoneal Permeability and Ascites
- Objectively Coding Intervention Fidelity During A Phone-Based Obesity Prevention Study
- Wake-up Strokes Are Similar to Known-Onset Morning Strokes in Severity and Outcome
- Endothelial Cells May Have Tissue-Specific Origins
- Acculturation and Subclinical Atherosclerosis among U.S. South Asians: Findings from the MASALA study
- Predictors of Obstructive Sleep Apnea Risk among Blacks with Metabolic Syndrome
Tackling increasing rates of obesity is likely to be a defining feature of health care over the next several decades. Adult obesity is a persistent and treatment-resistant problem. Consequently, an emerging theme in the literature is to commence prevention efforts earlier in the developmental time course.
The Michael & Susan Dell Center for Healthy Living ('the Center') is a public-private partnership that was developed to address child health issues through research, service, and education. This overview paper introduces a special issue of seven articles on childhood obesity from the Center, and the implications of this research for obesity prevention.
Research demonstrates a link between obesity and increased circulating inflammatory cytokines, which lead to changes in the microvasculature. Massive weight loss patients often experience delayed wound healing after body-contouring procedures; however, no studies exist to explore the inflammatory response of massive weight loss on microvasculature.
Lipidomics reveals associations of phospholipids with obesity and insulin resistance in young adults
Obesity and related diseases have become a global public health burden. Identifying biomarkers will lead to a better understanding of the underlying mechanisms associated with obesity and the pathways leading to insulin resistance (IR) and diabetes.
Obesity Suppresses Estrogen Receptor Beta Expression in Breast Cancer Cells via a HER2-Mediated Pathway
Obesity is associated with a worse breast cancer prognosis, while greater breast tumor estrogen receptor beta (ERβ) expression is correlated with improved therapy response and survival. The objective of this study was to determine the impact of obesity on breast cancer cell ERβ expression, which is currently unknown.
Although obesity and the associated metabolic syndrome negatively impact on health outcomes, a paradoxical relationship between obesity and mortality has been reported for specific patient populations - the "obesity paradox". However, underlying mechanisms remain unclear and several possible explanations are being discussed.
Selective Spectrum Antibiotic Modulation of the Gut Microbiome in Obesity and Diabetes Rodent Models
The gastrointestinal tract microbiome has been suggested as a potential therapeutic target for metabolic diseases such as obesity and Type 2 diabetes mellitus (T2DM). However, the relationship between changes in microbial communities and metabolic disease-phenotypes are still poorly understood.
The aim of this study was to investigate the shared molecular pathways of obesity and cancer by exploring the role of RIZ1 in obesity and the phospatidylinositol 3-kinase (PI3K)/V-Akt murine thymoma viral oncogene homolog (PKB) (AKT)/mechanistic target of rapamycin (mTOR) pathway.
Design of lifestyle intervention trials to prevent excessive gestational weight gain in women with overweight or obesity
The Lifestyle Interventions for Expectant Moms (LIFE-Moms) Consortium is designed to determine, in pregnant women with overweight or obesity, whether various behavioral and lifestyle interventions reduce excessive gestational weight gain (GWG) and subsequent adverse maternal and neonatal outcomes.
Journal of Obesity and Overweight
Journal of Obesity and Overweight (JOO) is an peer reviewed open access journal that publishes articles on all aspects of human obesity. It includes causes, management, implications of obesity, and related approaches for weight loss. Under the guidance of our Editorial Board members all the articles are peer reviewed and published. Our aim is to publish progressive research works related to public health and its medical development.
Online Submission SystemJournal of Obesity and Overweight is using online manuscript submission, review and tracking systems for quality and quick review processing. Review processing is performed by the editorial board members of Journal of Obesity and Overweight or outside experts; at least two independent reviewer's approval followed by editor approval is required for acceptance of any citable manuscript.