He is a (Italian) board certified radiologist with an extensive training in neuroradiology. He is performing clinically orientated research in the field of motor neuron disease focusing on understanding the relationship between disorders of the motor neuron disease spectrum and imaging markers of disease progression. Assessing whether imaging measures are reliable biomarkers of progression requires skills in measuring clinical function and quantitative imaging. His training in neuroradiology and experience in processing and analysis of advanced MRI techniques provided him with the background and expertise needed to carry out this research program. Over the past 6 years, He has carried out neuroimaging studies of pediatric and adult neurological disorders, acquiring expertise in quantitative methods of analysis in particular diffusion tensor imaging (DTI), and susceptibility weighted imaging (SWI).
1.Analysis of structural and functional magnetic resonance imaging biomarkers and the correlation between neuroimaging measures and measures of disease progression in patients with upper motor neuron forms of motor neuron disease.
2. Diffusion tensor imaging of the spinal cord
3. Application of DTI in congenital malformations of the CNS
4. Stroke imaging
5. Application of susceptibility weighted imaging in the study of neurodegenerative diseases.
