Journal of Proteomics and Genomics

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Highlights

Research Highlights

Intrinsic terminators in Mycoplasma hyopneumoniae transcription

Mycoplasma hyopneumoniae, an important pathogen of swine, exhibits a low guanine and cytosine (GC) content genome. M. hyopneumoniae genome is organised in long transcriptional units and promoter sequences have been mapped upstream of all transcription units.

Transcriptome and Genome Size Analysis of the Venus Flytrap

Dionaea muscipula is renowned from Darwin\'s studies of plant carnivory and the origins of species. To provide tools to analyze the evolution and functional genomics of D. muscipula, we sequenced a normalized cDNA library synthesized from mRNA isolated from D. muscipula flowers and traps.

Designed amyloid fibers as materials for selective carbon dioxide capture

New materials capable of binding carbon dioxide are essential for addressing climate change. Here, we demonstrate that amyloids, self-assembling protein fibers, are effective for selective carbon dioxide capture. Solid-state NMR proves that amyloid fibers containing alkylamine groups reversibly bind carbon dioxide via carbamate formation.

Proteomics of cancer stem cells

New understanding of cancer stem cell (CSC) biology continues to emerge due to development of novel methods in genomics andproteomics. Analysis of nucleic acids (RNA, DNA) is widely used to elucidate molecular perturbations in malignant tumors and carcinoma cells.

Rho Kinase Proteins Regulate Global miRNA Expression in Endothelial Cells.

Therapeutic targeting of Rho-Associated, Coiled-Coil Containing Protein Kinase (ROCK) signaling for tumor cells and tumor endothelium has shown efficacy in pre-clinical tumors models, and a better understanding of how proteins regulate tumor progression will strengthen our knowledge over disease etiology and treatment of patients with cancer.

Invasive cancer cells and metastasis

The physics of cancer is a relatively new emerging field of cancer research. In the last decade it has become a focus of biophysical research as well as becoming a novel focus for classical cancer research. This special section of Physical Biology focusing on invasive cancer cells and metastasis .

Reaction-diffusion in the NEURON simulator

In order to support research on the role of cell biological principles on the dynamics of neuronal response in health and disease, NEURON\\\'s Reaction-Diffusion (rxd) module in Python provides specification and simulation for these dynamics, coupled with the electrophysiological dynamics of the cell membrane.

Proteomic analysis of fetal programming-related obesity markers

To analyze fetal programming in rat brain using proteomic analysis and to identify fetal programming-related obesity markers. Sprague Dawley rats were divided into four feeding groups.

Acthi, a thiazole biosynthesis enzyme, is essential for thiamine biosynthesis and CPC production in Acremonium chrysogenum

The filamentous fungus Acremonium chrysogenum is an important industrial fungus and is used in the production of the β-lactam antibiotic cephalosporin C.

Physiological and Proteomics Analyses Reveal the Mechanism of Eichhornia crassipes Tolerance to High-Concentration Cadmium Stress Compared with Pistia stratiotes

Cadmium (Cd) pollution is an environmental problem worldwide. Phytoremediation is a convenient method of removing Cd from both soil and water, but its efficiency is still low, especially in aquatic environments.