Recent Articles

Chronic pain is a pandemic that has spawned the disproportionate opioid epidemic of overuse and overprescription in the United States. This challenge warrants review of physician education and curriculum to become more effective in pain management. Our current system for educating present and future physicians, as well as pain specialists, is flawed in a number of ways. The vast majority of physicians will encounter and manage chronic pain patients during their careers, but reviews have demonstrated dissatisfaction among medical students and practitioners with pain education and curriculum.

Ample research has examind the impact of autism for children and families, but less has addressed the effects of this condition for adults. The literature indicates that adults on the autism spectrum suffer from depression and have a heightened risk of suicidal ideation because of their social skills deficits [1]. Research also shows that individuals with high-functioning autism (HFA) can benefit from participating in support groups. In addition, research indicates that use of the term “neurodiversity” rather than other diagnostic labels encourages increased self-esteem to persons on the autism spectrum. This grounded theory study sought to understand the belief of clinicians with regard to the incorporation of the concept of neurodiversity in support groups for adults with HFA [2].

It is still contentious whether amyotrophic lateral sclerosis (ALS)-Alzheimer’s disease (AD) cases comprise a combined disease or represent a coincidental association. We describe the case of a 78-year-old white male with a 12-month history of bulbar muscle weakness and mild cognitive impairment. Hallmarks of AD pathology were present and associated with diffuse congophilic angiopathy. The motor cortex did not show a loss of motoneurons. The anterior horns of the medulla oblongata and hypoglossal nuclei showed skein-like cytoplasmic inclusions and ubiquitin and TDP43 phosphate positive staining. No signs of FTLD were detected. The pathological results suggest that, in this case, ALS and AD pathology appeared to be independent.

This study tested for the cardiac effects of Oprelvekin, recombinant human interleukin-11, a thrombopoietic growth factor, in patients afflicted with chemotherapy-induced thrombocytopenia (platelet count

Bovine respiratory disease complex remains one of the most economically important diseases of stocker cattle. Reports of myocardial injury associated with BRDC have been limited to necropsy findings. An animal-side diagnostic test for cardiac troponin I (cTnI) has been validated for use in cattle. The objective of this study was to determine the association of blood concentration of cTnI and pneumonia in stocker cattle. A proof-of-concept study was conducted using 16 calves (7 healthy; 9 BRDC).

A 55 year-old man with signs and symptoms of severe sepsis was admitted to the emergency department. He is severely obese with a BMI of 80 Kg/ m2 and a medical history of hypertension and arrhythmia. The abdominal pain was non-specific and the physical examination was impaired by obesity. Ultrasonography (US) was ineffective and no computed tomography (CT) scan was available for a patient of his weight. The acute abdomen presented an inflammatory etiology. The patient underwent laparoscopy and severe cholecystitis was diagnosed and treated. The patient recovered well, and remained for 36h in the intensive care unit and 5 days in the surgical ward.

The ‘holy grail’ of being able to assess reliability and truthfulness is investigated one step further via this case study utilising a credibility checklist with a road traffic accident claimant. The possibility of operationalising unreliability in a numerical, or at least, an informed narrative way is explored in this innovative study.

Preterm birth is one of the most common causes of neonatal morbidity and mortality worldwide. Furthermore, the mortality and morbidity are very high in extremely preterm infants born before 28 completed weeks of gestation or those with extremely low birth weight for gestational age (

Causes of vitamin B12 deficiency in children include decreased intake, abnormal absorption, and inborn errors of B12 transport and metabolism. Rare causes of abnormal cobalamin absorption include Imerslund-Grasbeck syndrome (IGS) and intrinsic factor deficiency (IFD). IGS and IFD are caused by defects in the genes CUBN, AMN, and GIF. We describe a 2 year old male who presented with severe megaloblastic anemia and methylmalonic acidemia. He was found to have a GIF heterozygous mutation c.79+1G>A associated with congenital gastric intrinsic factor deficiency and a novel variant c.960C>A in trans position.

The objectives of this study was to investigate the acid-base balance, blood gases, hematobiochemical profiles and the inflammation biomarkers fibrinogen, serum amyloid A (SAA) and haptoglobin (Hp) in the mammary and jugular veins of goats with mastitis. Blood samples were collected from the jugular and mammary veins from 26 goats with mastitis and from 10 healthy lactating goats. In diseased goats, the affected quarter had a remarkable degree of swelling, hard and sore to touch; the milk was bloody. In the jugular vein of diseased goats, the values of PCO2, PO2, base excess (BE), HCO3 and TCO2 were significantly lower than in the jugular vein of controls.

Antibiotics are one of the most widely used groups of drugs. The development of antimicrobial drugs represents one of the most important advances in therapeutics. Irrational and uncontrolled use of these agents both in developing and developed countries has resulted in an evolution of resistant strains in addition to a poor health outcome. Despite this fact, antimicrobial agents are vastly over-prescribed in the inpatient setting and the availability of antimicrobial agents without prescription in many developing countries. The use antimicrobial agents in Infants and children have become a routine practice for the treatment of pediatric illness and it needs study to show the status and pattern of antimicrobial in this age group is critical hence they are most vulnerable population groups to counteract illness

The objective of this study is to assess the relationship between food intake, nutritional status and good school performance among schoolchildren in the district of Abidjan. A cross-sectional study was carried out from December 2015 to April 2016 in 426 schoolchildren in Yopougon and Bingerville, two communes in the district of Abidjan. The nutritional status was defined starting from the BMI and calculated with Who Anthro Plus v1.0.4. The student and chi-square tests were used to compare the numbers and proportions. Binary and multiple logistic regressions have been used to see the association between good academic performance and the quality of food consumed and socio-demographic characteristics.

Obesity and physical inactivity are growing problems that are associated with major health problems. However, the current information on the association between obesity and physical activity (PA) in Saudi women of reproductive age is insufficient to design and develop intervention programs. To explore the rates of two types of obesity (general and abdominal obesity) and the level of PA and to evaluate the relationship between obesity risk factors, the use of exercise equipment at home, A cross-sectional study was conducted in 2014 using a stratified two-stage cluster sample. The sampling weight and design effect were incorporated into the analysis. Body mass index (BMI) and waist circumference (WC) data were collected from all participants.and obesity measurements.

NanotechnologyAbstractIntroductionIn order to successfully reduce the weight of a helical spring it is possible to optimize the material parameters or to use alternative advanced materials instead of conventional engineering ones. Springs are used for vibration damping in mechanical systems and are generally made of steel. As an alternative to material of steel springs in the scope of the study, mechanical behaviors of fiber reinforced polymer (FRP) composite helical springs have been investigated. The FRP composite material has made it possible to reduce the weight of helical spring without any reduction on load carrying capacity. Due to increasing competition and innovation in recent decades, vehicle industries show interest in replacing conventional steel spring with FRP composite helical spring which has advantages such as higher strength to weight ratio, higher stiffness, high impact energy absorption and lesser stresses. The study gives the brief look on the suitability of FRP composite helical springs on related mechanical systems. The objective of the present work is evaluation of the design, analysis and fabrication of FRP composite helical springs.

Between 2010-2014, Fundacion Huesped and the Youth for Health Network implemented a sexuality education program, dance4life, in public schools in Argentina. A process evaluation was conducted in 2014 to assess the implementation of the program between 2010 and 2013, and make preliminary assessments of the impact on youth sexual and reproductive health.

School represents a proper place for health promotion among youth. This study aimed to explore the determinants of an eventual school nutrition policy (SNP) development by studying the perceptions of youth coming from different social contexts in Lebanon. It was a qualitative study conducted among 48 children and adolescents aged between 10 and 14 years in 8 schools (4 private and 4 public) in rural and urban Lebanese regions. An exhaustive integrated conceptual framework was used to explore the perceived determinants at different levels of action, namely individual, community/interpersonal and organizational. Directed and semi-structured individual interviews were conducted with youth. Data from this research have been submitted to a thematic qualitative analysis to identify barriers and facilitators of SNP development in Lebanon. Coding guide was based on the integrated comprehensive conceptual framework. Transcripts were coded and revised by the 2 researchers for common themes.

Despite the high numbers of participants in both rugby league and union, literature on body image of male rugby players is somewhat limited. However, researchers have theorized that the exercise adopted by males may reflect different levels of dissatisfaction, especially in activities that require a large body build, or lean aesthetic physique. Therefore, this study aimed to explore the prevalence of body (dis)satisfaction in terms of muscularity and body fat, and secondly to identify areas of the body that require a change (in either increase/decrease in musculature or body fat) to improve body image.

Lumbosacral radicular pain (LRP) is a common symptom, its annual prevalence in the general population is reported to be from 9.9% to 25% and it is characterized by a shooting, radiating pain to one or more dermatomes, which is often caused by irritation of the corresponding nerve root. The initial treatment should be conservative with oral medications, exercise, and physiotherapy. When conservative treatments fail, epidural steroid injections and other interventional treatments should be considered. Surgical interventions are indicated when all other treatments have failed.

A 54 year old female presented for atrial fibrillation (AF) catheter cryoablation. She had experienced multiple pre-syncopal episodes prior to diagnosis and underwent a cardiac work-up including Holter monitor, transthoracic echocardiogram,stress test and tilt table test which was negative except for atrial fibrillation. She presented to the hospital for an AF ablation procedure under general anesthesia after transesophageal echocardiogram to rule out atrial thrombosis formation.

Case reports have been a method of scientific communication in the medical literature. Cases describing a clinical challenge faced by physicians and providing well-reasoned recommendations serve an important function in the clinical practice. Other values of case reports include generating clinical hypotheses and promoting scholarly education. They enhance critical thinking for practicing physicians, residents, and medical students. A case report can raise conceptual questions about particular clinical observation with the goal to generate a clinical hypothesis. This article highlights the value of case reports and describes their role in advancement of medicine with the intent to increase and improve case reporting.