Recent Articles

EPCs (Endothelial progenitor cells) are the precursors of endothelial cells that form the inner lining of blood vessels and are involved in neovascularization and re-endothelializaton of injured tissues. These cells have the potential for treating a multitude of angiogenic disorders giving a new hope in the arena of vascular biology. In the present study, we have demonstrated that cord blood derived expanded CD34+ cells can be differentiated into functional EPCs in vitro.

Actinobacillus pleuropneumoniae causes porcine pleuropneumonia, a disease which occurs world-wide and affects pigs of all ages. The study on the protective immune mechanism is not thoroughly clear. An outer membrane protein (OMP) was identified by screening a phage library of 3~8kb random DNA fragments of A. pleuropneumonia serotype 7.

It is widely known that many problems in the mathematical biology can be modeled by the differential equations, and the corresponding systems are usually called as biological dynamic systems.

The high mortality associated with ovarian cancer is generally related to the development of drug-resistant disease. HMGA2 protein, a member of the high-mobility group AT-hook (HMGA) family of non-histone chromatin binding factors, is overexpressed in high-grade serous ovarian and tubal carcinomas, though little is known about its contribution to disease progression and drug resistance. We sought to assess whether compositional changes in HMGA2 production were associated with ovarian cancer progression.

Ovarian cancer constitutes the second most common gynecological cancer with a five-year survival rate of 40%. Among the various histotypes associated with hereditary ovarian cancer, high-grade serous epithelial ovarian carcinoma (HGSEOC) is the most predominant and women with inherited mutations in BRCA1 have a lifetime risk of 40-60%. HGSEOC is a challenge for clinical oncologists, due to late presentation of patient, diagnosis and high rate of relapse. Ovarian tumors have a wide range of clinical presentations including development of ascites as a result of deregulated endothelial function thereby causing increased vascular permeability of peritoneal vessels.

Periodontal disease is a major oral health problem, in which specific species of bacteria play an important role in its progressing and severity. Because chronic periodontitis is believed to be asymptomatic in its initial stages, it has been suggested that individuals may be unaware of their clinical periodontal status [1-3] and underestimate what treatments are required, as judged by dental professionals [4].

Cardiac myxomas are a potential source of emboli to the brain and elsewhere in the vascular tree. Myxomas are the most common benign primary cardiac tumor in adults. The commonest location of cardiac myxomas is in the left atrium followed by the right atrium and the remainder develops in the ventricles and rarely in the heart valves.

In this era of implant dentistry, the teaching and indications for removable prosthodontics is becoming a lost art, especially in affluent urban environments, where most replacements are accomplished by the use of implant fixtures. Removable prosthodontics is still being taught and is used in rural areas and in the elderly patients or medically compromised individual.

Gallbladder carcinoma is a multifactorial disease with a complex interplay at molecular levels. Here we look at the expression of specific cytokines (TNF-α, IL-1β, IL-6, IL-8 and VEGF) in GBC patients to develop them as biomarkers of gallbladder cancer.

The ecosystem imbalance imposed by conventional agriculture is characterized by the loss of biodiversity that leads to uneven biological-energy distribution or to the disequilibrium of photosynthesis and respiration. These changes contribute to the excessive greenhouse gas accumulation in the atmosphere followed by global climate change.

Mitochondrial DNA (mtDNA) heteroplasmy has been found to be commonly present in many organisms. However, the studies on the mitochondrial heteroplasmy within group of fishes are currently lacking. This specific purpose of this study was to investigate the mtDNA heteroplasmy in different organs within group of common carp.

Age estimation from tooth – coronal index (TCI) using dental radiographs based on reduction in the size of the dental pulp cavity with advancing age as a result of secondary dentin deposition, has been presented.

The Novel, simple, sensitive, rapid, accurate and economical and reliable First derivative spectroscopic method has been developed for synthetic mixture of Dapagliflozin (DAPA) and Metformin hydrochloride (MET).

We report on a nine-month-old girl who presented with persisting cough, and diminished ventilation of the left hemithorax. Viral pneumonia was suspected after Adenovirus detection by PCR, but chest X-rays showed a persistent shadowing of the left hemithorax and persistent coughing despite clinical improvement. Because of the discrepancy between clinical and radiological signs further investigations by ultrasound and CT scan were performed, which visualized an intrathroracic tumor. Histopathology confirmed diagnosis of a teratoma.

Acquired Immune Deficiency Syndrome (AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV). They get it after being infected with the HIV virus. HIV (human immunodeficiency virus) is a retrovirus that primarily infects components of the immune system.

Cognitive waning due to chronic copper (Cu) intoxication in animal models is increasingly being reported; notwithstanding, information regarding molecular basis of Cu accumulation and neurobehavioral impairments remains fragmentary.

Thirty years of AIDS activism have taught us many invaluable lessons in responding to rapidly evolving global health epidemics. In this article, I apply five of them-innovative governance and financing; alternative incentives for biomedical research and development on neglected diseases; health systems strengthening; community and civil society engagement; and human rights protection-to the current Ebola epidemic.

Immunohistochemistry (IHC) was used to determine the protein levels of p27, CD117 and ki67 in tumor tissue of xenograft. After treatment of Fan, the morphologic changes were observed by DAPI staining, Hoechst staining and TUNEL detection under fluorescent microscopy.

Anthropometry is a systematic study of measurements on man and it involves scientific techniques for taking various measurements and somatic observations on the living man. As crime rate is increasing day by day, issue for human identification is of prime note. A forensic anthropologist would attempt to answer the following key questions relating to origin, age, sex, height and race after examining the remains.

Cephalofacial measurements and indices are used to estimate sex and race. The aim of this is to document the craniofacial characteristics and sex differences from cephalic index and facial index of the studied groups.