Recent Articles

The effects of the levonorgestrel-intrauterine system (LNG-IUS) on urinary and sexual functions of women with idiopathic menorrhagia were evaluated using two internationally validated questionnaire forms. This prospective study included (30-49) year-old women with idiopathic menorrhagia (n=91), who visited the Gynecology and Obstetrics Clinic of the hospital. The index of female sexual function (IFSF) questionnaire and the international consultation on incontinence modular questionnaire short form (ICIQ-UI) were used to evaluate sexual and urinary system functions, respectively, pre-, and 6 and 12 months post-LNG-IUS insertion. The IFSF scores were (mean ± SD) 27.1 ± 6.9, 30.0 ± 7.2, and 32.7 ± 7.5 at pre-, and 6 and 12 months post-LNG-IUS insertion, respectively (p

Mucormycosis is a rare but invasive and potentially lethal infection caused by ubiquitous fungi of the order Mucorales. The primary mode of infection is inhalation of fungal spores. Rhinocerebral and pulmonary infections are most common, however, other organ systems including the central nervous system can be affected, presumably by occult fungemia. We describe the prolonged treatment course (>1000 days) of a patient with cerebral mucormycosis using liposomal amphotericin B (LAMB). Two different attempts were made to replace LAMB with posaconazole, but each occasion resulted in therapeutic failure. This case represents the longest course of LAMB reported in the literature.

Foreign body ingestion and aspiration commonly affect children. The most vulnerable age is early childhood when children tend to explore new objects with their mouths or by an accident by elder siblings. A 2-year-old female child who is known to have congenital hypotonia, status post laparoscopic fundoplication and gastrostomy tube feeding (G- tube) inserted at age one year. Then she was in stable condition till when presented with acute unexplained drooling of frothy whitish secretions, mild cough and difficulty breathing with hypoxemia. X-ray chest and upper abdomen revealed normal. She underwent flexible bronchoscopy revealed normal and then direct laryngoscopy was extracted a covering plastic of the feeding tube in the upper end cervical oesophagus by Magill forceps technique. Subsequently her symptoms resolved completely. To increase the likelihood of identifying foreign body ingestion and aspiration, healthcare professionals should maintain a high index of suspicion even in children with neuromuscular disorder.

Detailed analysis of dynamic fungal cell wall components is crucial to our understanding of fungal systematics and the biology and physiology of fungal growth. In fungal pathogens this is of particular importance in examining their response to stress. However, current methodologies do not permit fast and accurate or quantitative analysis of cell wall carbohydrate components. Here, we provide a novel method permitting simultaneous quantitative analysis of the major cell wall components of Candida species relying on triple-staining with fluorescent labeling of chitin, β-glucans and mannans.

Routine intraoperative cholangiogram (IOC) during laparoscopic cholecystectomy (LC) helps to confirm biliary anatomy and reduce bile leaks. It also allows identification of common bile duct stones intraoperatively which in selected patients can be cleared transcystically in the same procedure which is much less morbid than through post-operative endoscopic retrograde cholangiopancreatography (ERCP). Despite this, some surgeons only selectively perform IOC or forgot it all together.

implantIntroductionThe implant technology developed as the all-on-four concept is offered as an alternative to conventional implant applications. In the all-on-four technique, 4 implants are placed in the interforaminal region in the mandible and in the pre-maxillary region in total edentulism cases. This application is based on the placement of two of these implants to the anterior region so as to be perpendicular to the occlusal plane, and on the placement of two implants to the posterior region so as to be inclined 30-45o. These implants are ensured to function by making immediate fixed complete denture over them. The patient is administered with permanent fixed full arch restoration 3 months later. The reduction of surgical procedures and the functioning of immediate dentures are important by means of this system. The purpose of this study is to compile the clinical and research articles regarding the all-on-four implant concept, to determine the basic principles of this concept, and to present the advantages and disadvantages of the method. The all-on-four concept can be an alternative and potential treatment method especially in atrophic edentulous jaws, its routine clinical practices can be performed, but it is necessary to increase long-term clinical controlled studies.

The lycopene is a known bioactive constituent of Lycopersicum esculentum and its application in diabetes is an active area of research. The lycopene has disadvantages such as susceptible to light, heat, and oxidants, which limit its therapeutic applications. In the present investigation, we reported lycopene niosomes formulation which can enhance its anti-diabetic application. The niosome formulation was prepared to preserve lycopene activity.

Tertiary education has always been regarded as highly stressful environment to students. Medical and health science training further add to the already stressful environment. Awareness of the existence of stress in medical students by physicians will help in diminishing student’s experience of stress. Therefore, identifying additional stressors in the clinical context is very crucial for providing measures to minimize students’ stress to a tolerable level and helping them to cope better. And the aim of this study is to assess perceived stress and factors associated with it among Bahir Dar University medical students, North West Ethiopia, 2016.

Patients with Goldenhar syndrome present as difficult airway to the anaesthesiologist due to various craniofacial anomalies like hemifacial microsomia, retrognathia and high arched palate. Also, these patients often undergo repeated surgeries for their various deformities. A, 4 year old female with Goldenhar syndrome and diagnosed as Right microphthalmos was posted for second stage lid reconstruction surgery. Previous anaesthesia records revealed no history of difficult intubation. During second stage, difficult intubation was encountered and eventually patient’s trachea was successfully intubated with C-MAC® D-blade videolaryngoscope.

The potency test for anthrax vaccines has historically involved the challenge of actively or passively immunized laboratory animals with a fully virulent strain of Bacillus anthracis. Lethal challenge studies with the archetypal virulent strains such as B. anthracis Ames strain present considerable difficulties in laboratory management and handling and are too inefficient for the early evaluation of alternative preventative and therapeutic interventions. An ELISA for the evaluation of antibody response to protective antigen (PA) in horses immunized with the Sterne 34F2 strain spore vaccine was developed. The objective of this work was to study the performance of this assay in terms of the guidelines set forth by the International Conference on Harmonics (ICH) and the Center for Biologics Evaluation and Research (CBER) for analytical procedures. We have demonstrated a working range for this assay (73-1581 EU/ml) on the bases of the following parameters: linearity (25 and 1,662 EU/ml, r2 = 0.9988, p < 0.001), accuracy (94.8 - 105.4 %, recovery within the range of 25 and 1,662 EU/ml), precision (≤ 17.6 % CV, repeatability; ≤ 15.7 and ≤ 13.1 % CV, intermediate precision per day and per analyst, respectively), limit of detection (2.25 EU/ml) and limit of quantitation (25 EU/ml). The assay was also demonstrated to be specific for the evaluation of anti-PA IgG antibodies. Based on the assay performance characteristics it was determined that the assay was adequate for use in B. anthracis immunogenicity testing in horses.

The London Metropolitan Police in collaboration with medical personnel, study all sudden unexpected death in infancy (SUDI)

Ten recently extracted primary molars, were used in this study for the measurement of the shear bond strength. Occlusal enamel was ground, leaving a flat dentin surface, on which a cylindrical specimen of each of the two tested materials was applied and light-cured according to the manufacturer’s instructions. Specimens were then mounted in self-cure acrylic resin. Ten specimens were used for the measurement of the compressive strength. The specimens were prepared in a special-cylindrical mold, then light-cured according to the manufacturer’s instructions. The compressive and shear bond strength of each specimen was measured using a Universal Testing Machine.Ten specimens of each of the two resin materials were used to measure the abrasion resistance. The test was performed by means of a toothbrushing machine and abrasive dentifrice slurry. The specimens were weighed before and after the test. Weight loss of the specimens were calculated after the test and reported as percent weight loss. Regarding microleakage test, Class V cavities were prepared in the buccal surface of 36 exfoliated or extracted human primary molars.

Bone healing is a complex process consisting of multiple sequential phases needing the coordinated interaction of various cells, growth factors, cytokines and mechanical conditions. However, bone healing is one of the rare regenerative processes resulting in complete restoration of form and function. Fracture treatment aims towards a swift return to functional use of the injured limb. Therefore stabilization is a key requisite. In the veterinary clinic difficult fracture cases often require a unique stabilization by custom made external fixation. While this fixation technique harbors risk factors it offers a high flexibility essentially needed to successfully treat small animal fracture patients. Here we draw the connection between the up-to-date knowledge in bone healing and case reports of external fixation techniques from the small animal practice with respect to benefits and risk factors.

Following the rise in popularity of forensic science, fueled by the media and perhaps necessity, comes the demand for an effective and productive approach to advising students interested in a career in this vast area. Forensic science is a large-scale umbrella term encompassing a multitude of disciplines. Whereas “forensic” means legal, any discipline that has an application to law or the legal system may be considered a “forensic science”. With the seemingly ever-increasing lure of forensic science as a career option, the question arises as to how best to assist students in making a dream job a reality. The purpose of this research is twofold: (1) summarize findings from forensic science job listings in the United States and (2) provide a framework, derived largely from Systems Theory, for understanding the advisee skillset, and suggest a model for a step by step career decision-making and curricular planning approach for professionals working in an advising capacity.

Maintaining a healthy body weight is important for overall health and can help prevent and control many chronic conditions. However, the information surrounding the barriers to healthy eating (HE) and physical activity (PA) for weight maintenance among Saudi women of reproductive age is insufficient to design and develop intervention programs. To explore personal, social, and physical environmental factors that act as barriers to maintaining a healthy weight and how these barriers vary by socio-demographic and weight status. A cross-sectional study was conducted in 2014 using a stratified two-stage cluster sampling design comprising 408 Saudi women attending 12 Jeddah Primary Health Centers (JPHCCs). Data was collected using a structured questionnaire consisting of socio-demographic factors, eating habits (EHs), PA, and perceived barriers to a maintenance of healthy weight maintenance. Body mass index (BMI) and waist circumference (WC) data also were obtained.

Thoracic ultrasonography has been used to evaluate pulmonary parenchyma and the macrocystis of the lung in a preterm with congenital cystic adenomatoid malformation type I. The images gained have been important for diagnosis and therapeutic strategies in our case. An infant was prematurely born with congenital cystic adenomatoid malformation type I. The chest X-ray and computerized tomography showed a great opaque area in the entire right lung, we considered performing a pneumonectomy. This opaque area hampered the expansion of left lung. After draining the macrocystis by ultrasonography-guided puncture, it was possible considering and performing the lobectomy due to the reduction of the volume of macrocystis. During follow up at 4 months, the infant did not show complications and the chest X-ray revealed the reduction of volume of the dense area in parenchyma of right lung.

The comorbid psychopathology that is well-established in ethnoracially diverse OEF/OIF/OND veterans also often coincides with other problems (e.g., legal and social). To mitigate the clinical side of these types of difficulties, the Veteran Administration Health Care Systems offers a wide range of mental health services. This article draws on an evidenced-based literature review to explore factors that are relative to delivering group psychotherapy in light of the entwined clinical and forensic matters sometimes confronting diverse veterans.

Stroke associated with malignancy is rapidly increasing. Lesion types mainly resemble cardio embolic multiple ischemic lesions. We present a rare stroke patient with both ischemic and hemorrhagic lesions simultaneously. The etiology of stroke was found to be due to lung cancer and essential thrombocytosis. Differential diagnosis in this case can help for further investigation of strokes with malignancy.

Demyelination induced by cuprizone-is a widely used experimental model to analyze processes of re- and demyelination in the central nervous system (CNS). Here we used C57BL/6 mice; a model of experimental autoimmune encephalomyelitis (EAE) mimicking important aspects of human multiple sclerosis, to evaluate effects of cuprizone-dependent demyelination on different parameters associated with autoimmune inflammation. The treatment of mice with cuprizone leads to a significant decrease of several indexes characterizing spontaneous and myelin oligodendrocyte glycoprotein (MOG35-55)

Objective: To evaluate the compliance of chemotherapy administration duration by comparing the peripheral venous catheter (PVC) route with the implantable venous access device (IVAD).Keywords: Chemotherapy; Gravity perfusion; Peripheral venous; Implantable venous access deviceIntroduction Methods: This was a retrospective study that analyzed 566 cycles of chemotherapy administered by PVC at the Cancer Unit of Yalgado Ouédraogo University Hospital and 258 cycles administered by IVAD at the Oncology Department of Treichville University Hospital in Abidjan. We compared the differences between the programmed duration of chemotherapy and the actual duration of administration according to the two routes of administration.