Recent Articles

Analyze the abortion of a pregnant 10-year-old girl who was repeatedly raped by her uncle in the state of Espirito Santo paralyzed Brazil. Pregnancy was revealed on the 7th of August, when the girl went to a local hospital suffering from abdominal pain. The girl claimed that she has been raped by the relative since she was 6 years old and that she did not report him to the authorities before, due to the fear caused by the uncle’s threats.

Since December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has reached catastrophic proportions. Many patients required admission to the intensive care units (ICU), stressing the capacity of public health systems. The workload in the emergency departments (ED), especially the ICU, has dramatically increased, creating a pressing need to optimize resources through risk stratification for critically ill COVID-19 patients.

Obesity is a chronic metabolic condition of energy imbalance where energy intake exceeds energy expenditure. Resting energy expenditure (REE) represents calories burned at rest and accounts for >60% of total energy expenditure and is an important target for management of obesity. Capsaicinoids, extracted from Capsicum annuum have previously been shown to increase metabolism, lipolysis & induce satiety.

Hepatitis B is an infectious disease that caused by hepatitis B virus infection. Hepatitis B virus replicates in the liver and causes both acute and chronic hepatitis. The virus predominantly transmitted through a blood and sexual contact from potential sources. Healthcare professionals are at great risk of occupational exposure to this virus.

Cefazolin sodium is a broad-spectrum antibiotic useful for the treatment of many Gram-positive and some Gram-negative bacterial infections. This study was designed to investigate the impact of the Trivedi Effect® on the structural properties and the isotopic abundance ratio of cefazolin sodium using LC-MS and GC-MS spectroscopy. Cefazolin sodium sample was divided into two parts, one part of cefazolin sodium was considered as control

Staphylococcus aureus is a serious risk to public health as it triggers human infections ranges from wound abscess to life threatening states. As involvement to the global effort the objectives of this study were to examine the incidence of Methicillin-resistant Staphylococcus aureus (MRSA) in Taif region, Saudi Arabia. Moreover, this work aimed to estimate the relation between the phenotypic antibiotic susceptibility patterns and the antibiotic resistance genes mong MRSA isolates. A total of 67 wound specimens were taken from patients. Methicillin-resistant Staphylococcus aureus (MRSA) was selected by growing on Mannitol Salt Agar supplemented with methicillin (5 mg/l). The prevalence of methicillin-sensitive S. aureus (MSSA) and methicillin-resistant (MRSA) wound carriage among patients was 51 and 49 %, respectively.

Opioids are commonly prescribed for acute pain management. Complications such as nausea, vomiting, itch and constipation are not uncommon. Two unusual and unexpected complications that can arise in the acute setting are opioid-induced hyperalgesia (OIH) and acute opioid tolerance (AOT). The diagnostic challenges of these two entities are mainly attributed to their unpredictable onset and lack of strict diagnostic criteria. In the pediatric setting, additional confounding factors such as separation anxiety, hunger, thirst and poor verbal communication further complicate discerning between the two phenomena.

Irrational use of antimicrobials in food animals is reported as a primary cause of antibiotic resistance (AMR) at the animal human interface with detrimental public health implications. Veterinarians are the main player for antimicrobial usage in food producing animals (FPAs). Therefore, this study was aimed to explore the key determinants of antibiotic prescription behavior among FPAs practitioners and its public health implications. For the purpose, a pre-tested questionnaire was presented to FPAs veterinarians.

Cowhide has been considered an alternative to meat for many years in Nigeria and other West-African countries. It is processed to be edible and deliciously inclusive in African recipes that call for assorted meats. The physicochemical properties assessed are pH, temperature, total suspended solids (TSS), total dissolved solids (TDS), total solids (TS), turbidity, salinity, biological oxygen demand (BOD), chemical oxygen demand (COD), total alkalinity, dissolved oxygen (DO), electrical conductivity (EC) chloride, nitrate, sulphate, phosphate, color, and odor.

Idiopathic pulmonary hemosiderosis (IPH) extremely rarely occurrs in adults according to current literature.We report one case of IPH in a middle-aged woman presenting with extensive central-predominant ground glass opacities and consolidation in the lungs. Since these imaging findings are not specific and can be similar to other diffuse pulmonary diseases, it is essential to have an deep understanding of this disorder. Imaging findings must be combined with clinical laboratory examination to make a diagnosis of IPH. Transbronchial lung biopsy (TBLB) is the gold standard for evaluation of suspected patients. We review the current literature and provide a recommendation based on discussion.

Cutaneous adnexal carcinomas are rare cutaneous malignant adnexal tumors derived from eccrine and apocrine sweat glands, follicular structures and sebaceous glands. They represent less than 1% of cutaneous cancers Porocarcinoma and hidradenocarcinoma are two main types of eccrine sweat carcinomas of unknown pathogenesis characterized by their clinicopathological diversity.

Diarrhoea is a common and diverse aetiology problem in HIV infected patients that can cause deterioration in the quality of life, malnutrition and failure of antiretroviral therapy (ART). Ibalizumab (IBA), a humanized monoclonal antibody that binds to domain 2 of CD4 T lymphocytes receptor, has been recently approved for treating adults infected with multidrug-resistant HIV-1 infection for whom it is otherwise not possible to construct a suppressive antiviral regimen.

Sampling methods and procedures impact outcomes in many different areas whether they are in compensations in product injury cases, jury selection, population estimation in census, forecasting national gross products, etc. Economic penalty and emotional injustice from faulty sampling methods ranges from life or death to irreparable economic and emotional damages

Patients with Philadelphia-negative myeloproliferative neoplasms (PN-MPN) are at a higher risk for venous thrombosis. Thromboelastometry may prove efficient to evaluate the patient’s thrombotic risk. In this study, based on data from 114 patients with PN-MPN from a single center in Greece, hemostatic profile was assessed with routine coagulation tests, Rotational Thromboelastometry (ROTEM® ), and Platelet Function Analyzer (PFA)-100 and correlated with clinical, laboratory, treatment characteristics, gene mutations and polymorphisms of poly (ADP-ribose) polymerase-1 (PARP-1)

Controlling osteoarthritic pain has emerged as a major health care challenge. Available treatments are either cytotoxic or addictive and therefore there is an urgent need to develop alternative treatment options. We previously developed a liposomal-alginate construct to improve local anesthetic delivery as a potential chronic pain management treatment.

Forty patients with CHDs who received liver biopsy to stage fibrosis and 12 normal subjects performed also shear wave elastography (SWE) and ELF-test. We chose two different outcomes for histological fibrosis (F0-F1 vs F2-F4) and (F0-F2 vs F3-F4). ELF-test and SWE were independent predictors, categorized using ROC analysis. Two scores called SCORE1 and SCORE2 were devised.

3D gas-solid coupled symmetrical numerical model was developed on the basis of multiphysics finite element platform to study coal seam fracture stimulation under the high pressure gas impact loading generated by the highly pressurized multi-discharge carbon dioxide gas fracturing technique to improve pre gas drainage efficiency. The purposes of this study are to understand the natural and operational factors contribute to coal seam fracture stimulation and improvement of coal seam gas drainage efficiency and the interaction of these parameters.

From Jan –2004 to Dec-2004, five patients were referred to the surgical department with a diagnosis of endocarditis refractory to medical therapy. Patients were all male, age ranging 16 years to 28 years with a mean of 22 years. All of the five patients had native valve endocarditis of the tricuspid valve with a history of drug addiction in common. Their presentations included, sepsis, failure and recurrent pulmonary embolism. Three of them had bacterial, while two had fungal infection which was proven after blood cultures. After resuscitation, stabilization and preoperative workup, tricuspid valvectomy was performed on these patients because of the destructive and irreparable nature of the native valve. Fortunately, all had uneventful recovery after surgery. Pre-operatively these patients were treated with antibiotics and antifungals, and continued thereafter for almost 4 to 6 weeks in the post-operative period. Postoperatively there was significant tricuspid regurgitation in a subset of patients who had a follow-up. The Left Ventricular (LV) function remained normal to moderate with a moderate pulmonary artery pressure. These patients were discharged on antibiotics and anti-failure medications as per the GDMT.

Donepezil is a potent, selective, noncompetitive and reversible inhibitor of acetylcholinesterase, commonly used for the treatment of Alzheimer’s disease. The form of orally disintegrating tablets (ODTs) is a good alternative dosage form for patients who have a difficulty in swallowing conventional tablets or capsules.