Recent Articles

The global leather industry is undergoing a profound transformation, driven by the relentless advancement of digital technolo gies. From automated design and precision manufacturing to data-driven supply chain management and hyper-targeted mar keting, digitalization is reshaping competitive landscapes worldwide

About 1 to 2% of all exocrine pancreatic neoplasms are Solid pseudopapillary neoplasms (SPNs) with strong predilection to girls and young women usually in their 2nd or 3rd decade of life [1]. SPNs can occasionally display aggressive behavior, local in vasion or distant metastasis (10-15% of cases).

For overall context, some key pharma and biotech companies’ activities in biotechnology for 2025 are provided as follows; 192 companies marketed 783 biotech products worldwide. The listed products are approved in the United States and Europe pri marily for the largest markets, and also include Australia, Canada, and Japan. Growth rate for biotech product approvals in United States is provided subsequently in 5-year intervals. USA approvals started slowly for 1980-1994, picked up in rate for 1995-2009, and grew quite rapidly 2010-2025: 5 in pre-1980 years; followed by + 5 in 1980-1984; + 19 in 1985-1989; + 24 in 1990-1994; + 56 in 1995-1999; + 66 in 2000-2004; + 48 in 2005-2009; + 81 in 2010-2014; + 158 in 2015-2019; + 207 in 2020-2024; + 73 in 2025-6/2026 [1&1/2 years]. A total of 742 product approvals occurred in USA, of which 81 have been dis continued because mostly being superseded by a superior product. An additional 123 biotech products have been approved by the European Union and Japan. Their worldwide cost was calculated to be $662 billion in 2025. The specific indications for th ese biotech products number over 750 addressing all therapeutic areas, often achieving substantial disease control, which could not be accomplished without them.

PWS is increasingly recognized as a “functional vital sign” and is associated with future health outcomes, including hospitaliza tion, cognitive decline, falls, and mortality [1-5]. A PWS > 1.0 m/s is generally associated with good health and functional inde pendence, whereas walking speeds < 0.6 m/s may represent a clinical “yellow ” for increased health risks and functional dec line [1-3]. Furthermore, a change of approximately 0.1 m/s is considered minimally detectable or clinically meaningful improve ment in walking performance [3-5]. However, walking safety and y may be d by multiple factors including age, sex, medical comorbidities, musculoskeletal impairment, and orthopedic surgical procedures [5-7].

Nigeria is home to several natural beauties and has a rich, diverse wildlife. Several factors threaten the survival of wild animals, including habitat loss, poaching, climate change, and wildlife diseases, especially those caused by gastrointestinal parasites [1]. Zoological gardens display collections of wild animals for research, conservation, education, and recreation. Animals in zoos are captured from their natural habitats and kept in man-made environments [2, 3].

Saliva calprotectin (sCLP) is a simple and inexpensive marker to detect oral neutrophil-induced inflammation [1,2] and is increased in patients with periodontitis (PO) [3] which is associated with severe pathologies such as cancer [4], metabolic syndrome [5], psoriasis [6] as well as bone loss [7], or brain [8], cardiovascular [9], or joints inflammation [10], all of which requires active prevention.

Cheiloscopy refers to the study of lip print patterns formed by grooves on the vermilion border of the lips. unique to individuals and remain stable throughout life, making them valuable in forensic identi cation. Lip prints develop during in utero period and are genetically determined.

According to population present in India with Internet access has developed significantly, with adolescents and young emerg ing adults including the majority of users. It is essential to understand the frequency, correlates, and impact of online gaming on the psychological well-being of gamers compared to non-gamers in contemporary society. Males are more prone to violent games, while girls are more likely to play non-violent ones. It is also vital to analyze any differences between these two cate gories of games [1].

Serum protein electrophoresis (SPE) is an informative test primarily used to detect abnormalities in the gamma region, particularly to identify monoclonal immunoglobulins (M- proteins) in multiple myeloma (MM). MM is the second most common hematologic cancer, mainly affecting adults over 65. This study presents SPE results from routine laboratory check- ups in healthy Bulgarian adults.

People Living with HIV (PLHIV) have a higher risk of mental health issues than the public. HIV and related infections can affect the brain and the rest of the nervous system. This may change how a person thinks and behaves. In addition, some medications used to treat HIV may have side effects that affect a person's mental health [1]. HIV causes significant inflammation in the body. This inflammation can cause neurological complications by damaging the spinal cord and brain, which form the central nervous system. Despite effective Antiretroviral (ART), people with HIV are still at risk for central nervous system diseases associated with HIV. These diseases can be neurological (affecting the nervous system) or neurocognitive (affecting cognition or mental processing).

Age related changes in combination of voice and swallowing are often unaddressed in geriatric population. The study highlights the coexistence of presbyphonia and presbyphagia. Early diagnosis and providing appropriate intervention strategies can help improve the individual’s quality of life.

The results of the HER2-Positive Advanced Breast Cancer trial presented by Dr. Sara M. Tolaney at the ASCO Annual Meeting 2025, shows a promising new treatment for metastatic HER2-positive breast cancer. The study found that using T-DXd with pertuzumab nearly doubles how long patients can control their disease compared to the standard treatment, THP.1.

The results highlight the notetaking findings from the PISCES trial conducted by Dr. Charmaine E. Lok, who studied the impact of fish-oil supplementation on cardiovascular diseases among the haemodialysis patients. Between November 28, 2013, and July 22, 2019, 1,228 participants were under randomized case-study, with 610 assigned to the fish-oil group and 618 to the placebo group [1]. Over a follow-up period of 3.5 years, results showed a noticeable lower rate of serious cardiovascular diseases in the fish-oil group (0.31 vs. 0.61 per 1000 patient days), providing a hazard ratio of 0.57 (95% CI, 0.47 to 0.70; P

In the SYNCHRONIZE-1 trial conducted by Le Roux CW, the efficacy and safety of Survodutide for the treatment of obesity were analyzed in patients aged 18 or older with a BMI of 30 or above (meaning obese); patients with a BMI of 27 or above with at least one overweight-related health issue like hypertension, etc.; and patients having a history of unsuccessful dietary weight loss.

Antibiotics are especially used in obstetric practice during c-section as there is greater chance of postoperative infection.

Pseudotrimezia juncifolia popularly known in Brazil as ruibarbo or beressol, is an endemic species, particularly found in the Cerrado and Atlantic Forest regions of Brazil.

Motorcycle-related head injuries remain a major public health concern in low- and middle-income countries. Although helmet use is an effective preventive measure, compliance remains inconsistent due to various contextual factors.

Soil-borne pathogens and drought stress represent significant constraints to wheat production in arid and semi-arid regions. Biofumigation utilizing Brassica residues and application of arbuscular mycorrhizal fungi (AMF) constitute sustainable approaches for plant protection and abiotic stress mitigation.

Insufficient iodine intake can lead to iodine deficiency, which is associated with thyroid gland dysfunction and a group of abnormalities known as Iodine Deficiency Disorders.

This study evaluated horse owner awareness and management practices for tick control, and assessed the effectiveness of 0.1% deltamethrin in reducing tick infestations in horses in Lesotho.