Recent Articles

Resilience is recovering soon from a disaster or calamity. It is bouncing back quickly or refusing to remain falling. The health system in developing countries is still struggling with issues of universal coverage and sustainable and resilient health systems. There is a gap in evidence regarding strategies to build resilient health systems, particularly in developing countries.

Background: Lower respiratory tract infections (LRTIs) frequently require immediate empirical antibiotic therapy due to di agnostic delays and clinical severity. Empirical regimens commonly rely on broad-spectrum agents, which can increase selec tive pressure for antimicrobial resistance.

The global rise in obesity presents a significant public health challenge, with implications extending beyond metabolic disor ders to include an increased risk of cognitive decline and dementia.

Media strongly influences children’s eating habits, promoting consumption of sugary and ultra-processed foods.

Fusarium wilt disease of tomato is caused by Fusarium oxysporum f.sp. lycopersici and is a limiting factor to tomato production in Nigeria.

Sub-Saharan Africa has experienced substantial declines in new HIV infections over the past decade; however, these gains have not been uniform across populations. In Mozambique, married women remain a largely overlooked group in HIV prevention strategies, despite persistently high HIV prevalence.

Maternal insufficient calcium consumption can raise the risk of pregnancy-related problems such preeclampsia and gestational hypertension, which are linked to considerable morbidity and mortality in both the mother and the newborn.

Aberrant activation of the rearranged during transfection (RET) signaling pathway contributes to tumorigenesis and therapeutic resistance across multiple cancer types, including thyroid, lung, and breast malignancies.

Solid tumors are challenging to treat due to their heterogeneity, immunosuppressive microenvironments, and resistance to PD-1/PD-L1 inhibitors.

Acute Myeloid Leukemia (AML) is an aggressive hematologic malignancy that may arise de novo or secondary to cytotoxic therapies. Cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i), such as palbociclib, ribociclib, and abemaciclib are widely used in the treatment of hormone receptor-positive breast cancer (HR+BC) and have a tolerable safety prole compared to conventional chemotherapy agents applied in this space.

Poultry salmonellosis is considered as one of the devastating disease aecting the poultry industry. Cross-sectional study was conducted in semi-intensive poultry farms at Hawassa city, with the objectives of isolation,identification and antimicrobial susceptibility test of Salmonella.

Salivary calprotectin (CPL) is a marker of neutrophil-induced inflammation associated with periodontitis (PO). Inducible-nitric oxide (iNO) is a marker of eosinophilic inflammation. Hydrogen sulphide (H2S) is a marker of antioxidative activity, vasodilatation and good diversity of gut microbiota.

Numerous technical scientific advances, especially regarding antiretroviral technologies (ART), have allowed the prognosis of those infected by the virus to transform from rapid and inevitable illness to a life expectancy similar to that of people living without the virus [1]. Continuous treatment prevents opportunistic infections in people already diagnosed and the appearance of new HIV infections, either by sexual, vertical, or horizontal transmission.

Traditional cervical cancer screening methods, such as the Papanicolaou (Pap) smear, were underutilized due to several barriers.

Adolescent obesity is a significant public health threat in Malaysia, with one in three adolescents classified as overweight or obese. However, there is limited research examining the knowledge, attitudes, and practices (KAP) related to healthy lifestyles among target population. This study aims to provide a baseline understanding of their knowledge gaps and to explore the relationship between sociodemographic characteristics and KAP scores.

Objective: This systematic review aimed to evaluate the effectiveness of yoga as a therapeutic intervention for reducing anxi ety symptoms, improving comorbid depression and somatic complaints, and enhancing quality of life in adults with Gener alized Anxiety Disorder (GAD). Methods: A systematic search of PubMed and CINAHL was conducted up to August 2025. The review was registered in PROSPERO (CRD420251152980). Eligible studies included randomized controlled and clinical trials evaluating yoga inter ventions in adults diagnosed with GAD based on DSM criteria. Data extraction focused on intervention type, outcomes, and treatment effects. Risk of bias was assessed using Joanna Briggs Institute (JBI) tools, and results were synthesized narratively due to heterogeneity

The technique of sentinel lymph node biopsy has been widely used in early endometrial cancer in recent years, and a large number of evidence-based medical studies have now supported the therapeutic efficacy of sentinel lymph node biopsy as an alternative to traditional systematic lymph node dissection.

Bovine Trypanosomiasis known as Gendi in Ethiopia, is one of the major diseases of livestock. The disease results in loss of livestock and agricultural productivity with severe socio-economic impacts. The aim of this study was to assess the knowledge, attitude and practices of the community towards Bovine Trypanosomiasis in selected areas of Loka Abaya district, Sidama, Ethiopia. Descriptive cross-sectional survey was conducted using a semi-structured questionnaire by face-to-face interview and information was collected on knowledge, attitudes, control and treatment practices associated with Bovine Try panosomiasis. The Results showed that all the respondents have knowledge of tsetse and Trypanosomiasis. They heard about the disease and tsetse fly in different ways, i.e., from the community, animal health workers and when their animal was sick. Majority (66.7 %) treat their animals with trypanocide when infected. They buy drug from local dispenser’s and treat and administer the drug themselves not by veterinary professionals. The study revealed that the respondents have con siderable knowledge about Bovine trypanosomiasis and tsetse, as important factors in disease control and treatment. However, the misuse and unsystematic use of some trypanocidal drugs by the community is reported to be one of the predisposing factors for the development of drug resistance which has become a menace in the control of the disease. Therefore, regulatory enforcement and thorough education on the use of drug and treatment should be considered by the veterinarians and other stakeholders

Abstract: Umbilical cord blood contains stem cells which are useful in chemotherapy, implantation; however, cord RBC is considered as a waste product. It is necessary to use the umbilical cord blood for neonatal blood transfusion to avoid diseases. Nowadays, nanoparticles are used in biomedical and pharmaceutical industry. Nanoparticles interact with blood via different routes. In addition, these nanoparticles used in biomedicine, drug delivery, bioimaging, and to increase the shelf life of RBC. Nevertheless, research of nanoparticle interaction with umbilical cord red blood cells is still . in the present study, interaction between umbilical cord blood-RBC and citrate-stabilized gold nanoparticles is studied. Methods: Umbilical cord rbc isolated from whole blood immediately r the collection using centrifuge. PBS r is used as a physiological media and washing reagent. interaction of isolated RBC (2% suspension) with t con centration of citrate stabilized gold nanoparticle were investigated using UV-Visible spectroscopy, Raman spectroscopy, and Interfacial tension measurement technique. Results: UV-Visible spectroscopy is used to investigate the changes in Soret band and oxygenation bands (Q1 and Q2). Variation in absorption intensity is observed in umbilical cord RBC incubated citrate stabilized gold nanoparticles. However, there is no t shi in Soret band and Q1, Q2 band of cord-RBC with Au nanoparticles. In case of Raman spectros copy, enhancement in disulphide band region (526 cm-1 and 579 cm-1) and change in the spin state marker is investigated. While, interfacial tension decreases for 10 �l and increases for 100 �l and 200�l of 40 nM AuNP.

Diabetes is a chronic disease in which the body cannot properly use or store glucose. Glucose is a type of sugar that raises blood sugar levels if it accumulates in the blood. Diabetes occurs when the pancreas is no longer able to produce insulin, or the body is unable to use the insulin produced properly. Insulin is a hormone secreted by the pancreas that acts like a switch, allowing glucose to enter the body's cells from the bloodstream for energy. All carbohydrate foods are broken down into glucose in the body. The hormone insulin helps glucose enter the cells. Inability to produce insulin or to use it effectively leads to an increase in the level of glucose in the blood, which is called hyperglycemia. In the long term, high blood glucose levels are associated with damage to the body and failure of various organs and tissues [1, 2]