Recent Articles

Historical approaches to managing urachal anomalies in adult patients have shown a lack of denitive consensus between conservative and surgical management strategies. Our objective was to assess and consolidate existing literature regarding the diagnosis and treatment of asymptomatic urachal anomalies in adult patients.

Pulmonary nocardiosis is a rare chronic suppurative granulomatous disease, which is easily misdiagnosed as lung cancer and other diseases. Early diagnosis is beneficial to the patients rehabilitation. We herein report a case of myasthenia gravis in a 64 year old female patient with a space occupying lesion in the right lower lung

National Lung Cancer Screening programs have evolved in their implementation worldwide. This manuscript is delivered by a multidisciplinary panel in lung cancer screening. It aims to identify and present existing evidence regarding similarities and differences as well as teachable moments that have arisen through national implementation of lung cancer screening programs.

Levonorgestrel, an emergency oral drug, prevents unwanted pregnancies after unprotected sexual intercourse. It functions similarly to progesterone, allowing for the prevention of pregnancy if administered within a stipulated period. Glutathione is an antioxidant that protects against free radicals and xenobiotic substances

We present a 2-year-old boy known case of Spinal muscular atrophy type 2 presented with acute onset quadriparesis following a trivial trauma. On admission child had flaccid quadriparesis without bladder-bowel or respiratory involvement. His blood investigations, MRI Spine and Brain were unremarkable.

The detection of pathogenic bacteria is vital to food safety. Pathogenic bacteria are monitored by traditional culture-based methods (Ministry of Food and Drug Safety, 2019). However, several molecular methods are also used to detect food-borne pathogenic bacteria. These include conventional PCR (polymerase chain reaction), real-time PCR, and loop-mediated isothermal DNA amplification (LAMP) [1]

End stage renal disease in patients with junctional epidermolysis bullosa (JEB) pose distinctive clinical and management challenges. Their fragile skin, frequent infections, nutritional deficiencies, and ongoing inflammation can fasten kidney deterioration. Creating and maintaining dialysis access is especially dicult in these individuals, as their delicate skin and poor wound healing often result in repeated access issues or serious complications. Here we report a case of 23 year old female who after initiation of hemodialysis started to develop blistering disease with occurrence of multiple bulla over skin and mucous membrane and faced multiple issues in creating vascular access.

Although the discovery of the V617F mutation in the JAK2 gene has modified the understanding and treatment of polycythemia vera (PV), some patients display complex characteristics not recognized in the recent 2022 WHO classification. In the case reported here, no JAK2V617F nor JAK2 exon 12 mutations were identified

The steady population growth in Rajshahi City has led to an increase in construction activities to fulfill its growing infrastructural demand. The aim of this study is to assess the impacts of these urban construction activities on urban communities' physical and mental health in Rajshahi City. We applied a mixed-method approach to carry out this study. Data were collected through a semi-structured questionnaire from 150 respondents who are residing near ongoing major construction sites.

Penicillin and streptomycin are the most commonly used to prevent bacterial infection or contamination in cell culture. However, the role of Penicillin-streptomycin in inducing mouse embryonic stem cells (mESCs) to differentiate into cardiomyocytes is unclear. To illustrate the mechanism of penicillin-streptomycin on inducing mESCs differentiation into cardiomyocytes, we firstly investigated mESCs differentiation into cardiomyocytes by the traditional method. e timespace expressions of cardiac-specific genes were detected by real-time PCR and western blotting at 8 different time-points over a period of 36 days.

Objective: The aim of this project consists of the evaluation of the cell viability of adipose tissue (AT) harvested using the Superficial Enhanced Fluid Fat Injection (SEFFI) procedure standardized by the Authors (AG, FPB). The harvesting procedure was performed using two different cannulas having 0.8 mm and 1 mm side-port holes, respectively. Cells phe- notype and ability to adhere to the plastic surface have been analysed. 'Ihe results have been compared to those recorded in adipose tissue harvested using a liposuction system and processed with enzymatic digestion (collagenase).

Abstract Purpose: In this article, we review main clinical trials reported in the past decade. Methods: Stem cells are relatively undifferentiated, with unlimited proliferative ability; self-renewal capability and also they can differentiate into specialized cells. Somatic stem cells in adult organisms are responsible for regenerating and self-renewing tissue, Many different stem cell types reside in the eye. Results: One of the most important stem cells is limbal stem cell that retains in an undifferentiated state and exists in an optimal microenvironment or "niche". The importance of limbal stem cells in maintaining the corneal epithelium throughout life has long been recognized. Furthermore, stem cells in the retina have been for treatment of the retinal degeneration, which generally results in constant visual disturbance or even blindness. Conclusion: This review will briefly focus on the principal stem cells in the eye especially limbal stem cells.

Introduction: Buccal mucosal urethroplasty has revolutionized the surgical management of urethral strictures but the success of the procedure has been variable in different series. We have attempted to understand the interplay between buccal mucosal epithelial cells (BME) and the fibroblasts at the molecular level using connective tissue growth factor (CTGF) as a marker so that translation of this information would help in better urethroplasty outcomes.

In Brazil, the incidence of spinal cord injury (SCI) reaches 40 new cases/year/million. In other words, there are almost 6 to 8 thousand new cases per year, 80% of which are males, and 60% fall between the ages of 10 and 30.

Colorectal cancer (CRC) ranks as the third most common cancer and the second leading cause of cancer-related mortality globally, following lung cancer, in 2022 [1]. The etiology of CRC involves both environmental and hereditary factors, with environmental factors accounting for approximately 65% of CRC cases

Temporomandibular disorders (TMD) are a group of disorders that damage the temporomandibular joint (TMJ) and the muscles of mastication. They are commonly associated with parafunctional habits and clinical symptoms, such as headache, clicking, limitation of lateral movement, protrusion, and mouth opening, discomfort in the TMJ region, and vertigo

In recent years, gastrointestinal malignancies have ranked as the primary cause of cancer-related deaths across the globe. Despite remarkable progress in medical technology and treatment modalities, the majority of patients still experience local relapse and distant metastasis.It remains imperative to carry out in-depth investigations into the mechanisms underlying the occurrence and develpment of gastriointestinal tumours. Metabolic reprogramming

The objective of this study was to evaluate the bond strength of fiberglass posts cemented with Rely X U200 and Rely X Luting 2, with (A) and without (WA) ultrasonic activation in the root canal of bovine teeth. The penetration of the cements into dentine tubules was also assessed. Methods: Forty bovine incisors were selected and endodontically treated, and then divided into 4 groups (n = 10). Fiberglass posts were cemented with Rely X U200 and Rely X Luting 2 and activated with an ITSMO ultrasound insert in 2 groups; the other two groups received no ultrasonic activation. After 24 hours of cementation, the roots were sectioned into slices of approximately 1 mm each.

Gastric cancer (GC) continues to pose a significant global health challenge, particularly in advanced stages where treatment options are severely constrained. Immunotherapy represents a groundbreaking advancement in cancer treatment, exhibiting promising therapeutic effects in patients diagnosed with gastric cancer

Background: Oral cancer, a malignancy that manifests in the oral cavity, poses a significant health challenge globally. With its intricate interplay of genetic, environmental, and lifestyle factors, oral cancer has become a prevalent concern, demanding in-depth exploration and analysis