Recent Articles

We present a case of total esophageal reconstruction with a free Jejunal flap in a patient with a history of esophagectomy and two previous failed attempts at reconstruction. Despite the technique here described offers a reliable option when the stomach and colon are not available, the success of the reconstruction might be compromised by the onset of a perforated ulcer at the gastric blind pouch related to previows failed gastric pull-up (GPU) After a major reconstructive surgery of long hours, gastric pouch may develop ulcer with perforation and fatal empyema due to Stress, although the severe complication is rare. Surgeons performing esophageal reconstruction should be aware of the risks related to the presence of the blind pouch, The indications and limits of the reconstructive technique used as well as the rapid development of this unexpected and severe complication are discussed.

Cirrhosis is an end-stage liver disease. Patients with cirrhosis characterized by manifestations of portal hypertension and impairment of liver function. When the natural course of the disease progressed from compensated status to decompensated one, life expectancy of the patients would be shorted obviously. Complications including refractory ascites, spontaneous bacterial peritonitis,variceal bleeding.

lymphoproliferative disorders and opportunistic infections in IBD patients treated with immunomodulators is a concern, EBV status. Combination therapy (thiopurines plus biologics such as anti-Tumour Necrosis Factor (TNF) agents) is perceived to have higher complication rates and there is more concern about the risk of lymphoproliferative disease than for patients on single modality therapy. We present two reports of patients treated with combination therapy for IBD who presented with lymphoma within weeks of each other and review the evidence for the increased risk with this therapy.

HIV/AIDS occupy a special place among other diseases. It is Incurable and frightening disease, causing anger and denial.

Summary: Recent studies suggest a potential relationship between helicobacter pylori (HP) infection and small intestinal bacterial overgrowth (SIBO). The state of the digestive tract microflora is not often taken into account in the treatment of children with chronic gastroduodenal pathology associated with HP. The purpose of this study was to determine the frequency of SIBO in children with duodenal ulcer disease (DUD) and functional dyspepsia associated with HP

Objective and Design: The aim of this project was to evaluate the influence of inflammatory cytokines IL- and IL-8 on gastric •pithelial-mesenchymal transition in gastric epithelial cells.

Spinal muscular atrophy is an autosomal recessive disorder characterized by degeneration of alpha motor in anterior horn cells of brain and spinal cord, which results in muscular atrophy, hypotonia, fasciculations, areexia, paralysis and even death in most severe cases. The underlying cause of this disease is biallelic loss of survival motor neuron 1 (SMN1) gene. Depending upon the clinical features & patient's age, SMA is classied into dierent distinctive sub types.

Escherichia coli is the commonest Bacteria for urinary tract Infection do regulate its transcription predominantly at the stage of initiation by repressors and/or activators.

Out of 31 patients evaluated by serology for Echinococcosis during the study period, 7 (22.58%) were seropositive. Liver was the most frequent site involved (24 patients; 77.77%). Second organ the lung 5(16.13%) bone 1(3.23%) and the optic 1(3.22%). Of the respectively

lesion, known as invasive or aggressive candidiasis, can be extremely refractory to treatment. confused by the fact that the patient was a chain smoker, and also because the initial MRI images were strongly suggestive of an invasive malignancy. When clinical and radiological signs exactly mimic a malignancy, the picture is confusing.

According to UNASID report in 2018 Women continue to account for a disproportionate percentage of new HIV infections among adults (aged 15 and older) in sub-Saharan Africa: they represented 59% of the 980 000 million [820 000–1 100 000] new adult HIV infections in 2017 with available data

The study was approved by the The Medical Ethics Committee of the Cardiovascular Institute and our Hospital. All meth ods were performed in accordance with relevant guidelines and regulations. The written informed consent was obtained from the patients

Abstract coordinates are needed in some applications for polygons with concave vertices. Such elements do not have rational barycentrics and mean-value coordinates (Floater, 2003) [1

Solution blow spinning (SBS) o ers an easily adaptable alternative that has the potential to generate on-demand conformal nano ber mats directly on a wide range of targets. e present study demonstrates the facile fabrication of polycaprolactone (PCL)-gelatin nano bers using only a commercial airbrush and compressed gas. e PCL content increased mechanical strength, and gelatin content enhanced cell adhesion, proliferation, and acceleration of the biodegradation rate. An animal study was then used to demonstrate some of the possible surgical applications, including use as a surgical hemostatic, as a surgical sealant, and in tissue reconstruction

Inflammation arises through a complex network of dozens of molecules (including interleukin, interferon, chemo-kine, tumor necrosis factors, and acute-phase proteins) and many cell types (including monocytes, granulocytes, mast cells, and lymphocytes) [1-3]. Among the numerous cytokines involved in inflammation, the interleukin 1 (IL-1) family is involved in almost all types of inflammation and is an important inflammatory therapeutic target [1,2,4]. Interleukin 1 (IL-1) family members are central mediators of innate immunity and inflammation. In systemic or local pathological conditions such as tissue injury [5-7]

Laboratory studies of the patient suggested the existence of measles virus infection after the measles vaccination, EBV infection, combined with its iron protein, abnormal level of lipid, and hemophagocytes in the bone marrow smear indicated that the patient caught a EBV related hemophagocytic lymphohistiocytosis syndrome co-infected with measles.

Twelve patients with complex pelvic acetabular fractures were randomly divided into 3D group and conventional group, 6 cases in each group. Before operation, all patients completed routine examinations such as whole blood analysis, coagulation analysis, electrolyte of liver and kidney function, blood glucose, complete set before blood transfusion, urine analysis, electrocardiogram, color

The infection of Human Papillomavirus has remained the major health problem globally, with striking disparities between low-, middle-, and high-income countries in rates of infection, the attendant viral disease impacts, and access to preventive measures. This systematic review has looked into key health indicators in terms of prevalence and incidence of infection, the burden of cervical cancer, vaccination coverage, and screening programs across these economic categories in light of human papillomavirus infection

Immunosenescence describes the decrease in immune function with advancing age, a phenomenon that is associated with changes in the B and T lymphocyte populations. CD8+ T cells display the most dramatic phenotypical and functional changes within the T cell compartment whereby the cohorts of effector and memory T cells expand while the total population and diversity of naive T cells both decline.

Background and objectives: The early differentiation between infectious and non-infectious sepsis remains a challenge due to the lack of a reliable, ready available and quick biomarker of bacterial sepsis. This study aims to determine the diagnostic accuracies of procalcitonin (PCT), C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) as individual and combined predictors of bacterial sepsis, when compared to the gold standard microbiological cultures