Recent Articles

The epithelial-mesenchymal transition (EMT) event in carcinogenesis is dependent on multiple operant pathways of master transcription as proposed for NF-kappaB and in terms of the initiated progression of malignant transformation. Inflammation is a primarily compartmentalized series of distinct and overlapping systems that induce and enhance multifocal operabilities within both the nucleus and cytoplasm by systems of enhancer/inhibitory modes of modulation of multi-gene transcription.

The removal of pesticides in the environment mainly depends on natural degradation, especially on microbial degradation. Biodegradation has many advantages, such as complete degradation, no secondary pollution, quick effect and wide spectrum. Based on the single-factor experiments and Box-Benhnken design, the effect of four factors on the degradation of chlorpyrifos by P. stutzeri ZH-1 was investigated.

The aim of this study is to estimate the age-dependent force of infection for hepatitis B virus (HBV) for sick patients showing symptoms, blood donors and people coming to the serology department to test for the antigen in blood voluntarily. A secondary data was obtained from the serology department at the Komfo Anokye Teaching Hospital (KATH, January 2013- June 2016).

In a number of applications, one has access to high-dimensional time series data on several related subjects. Natural example comes from medical experiments: brain fMRI time series data for various groups of patients, be it controls or individuals with a specific mental disorder.

Kaani Tribes have traditionally depended on harvests of forest, wildlife, and forest products. The main objective of this study was to see if the Kaani tribes have lost the knowledge and use of herbs in treating diseases while relocating to city life. Ethnomedicinal data was collected through Participatory Town Appraisal (PRA), which is based on interaction with indigenous people and direct observation in the field and interviews and discussions with Mootukani, the medicine man for the tribals.

Aim: The aim of this study is to evaluate the effect of Transtheoretical Model (Stage of Change Model) based smoking cessation program on among high school students.

An experiment was conducted to investigate the effect of cereal sources (corn or wheat) and omitting premix from finisher diets (from 29 to 42 days of age) on broiler performance, carcass measurements, and blood biochemical properties.

The synthesis of ternary quantum dots (TQDs) have a significant effect on the use of nano scale crystals in biology, photonics and photovoltaic. Rather than controlling the size of TQDs, making three-component TQDs is also an approach to changing the energy of their barrier width, typically using three-component substances such as Znx Cd1-xSe.

In the conventional XRR analysis, the X-ray reflectivity has been calculated based on the Parratt formalism, accounting for the effect of roughness by the theory of Nevot-Croce conventionally. However, the calculated results have shown often strange behaviour where interference effects would increase at a rough surface.

A variety of agents are used during any surgical procedure to control intraoperative bleeding. Most of them are meant to be removed at the end of the procedure. Sometimes these are accidentally forgotten at the operative site which may present with different clinical symptoms subsequently.

Cystic lymphangioma is a benign tumor of dysembryological origin. It is a rare disease; its annual incidence is estimated at 1 /20,000 in children and 1 / 100,000 in adults [1]. Its abdominal localization is rarer, with 2% of cases of cystic lymphangiomas; but the cystic lymphangioma of the mesentery remains the most frequent variety of this abdominal topography [2]. Through this observation and a review of the literature, we recall the epidemiological and evolutionary aspects of this pathology.

The mandible is one of the most frequently fractured bones in the facial skeleton. Postoperative pain control is an important outcome in assessing overall treatment success and patient satisfaction. However, few focused studies have reviewed protocols for postoperative pain management in patients with mandibular trauma. The aim of this study is to evaluate the protocol for the management of postoperative pain in patients undergoing surgery for a mandibular fracture in our department.

Usual fluctuations of sex hormones during the estrous cycle in female mice affect the hippocampal neurogenesis. The hippocampus also comprises many steroid receptors suggesting the modulatory effects of gonadal hormones on the hippocampal plasticity. Sex differences at the level of structure and function of the hippocampus are mostly due to the fluctuations of steroid hormones during the estrous cycle. The purpose of this study was to investigate relationship with serum sex hormone levels and the expression of glial fibrillary acidic protein (GFAP) at different phases of the estrous cycle.

ATP-binding cassette (ABC) transporters are the largest and most ancient family of transmembrane proteins with representatives in all phyla from prokaryotes to humans. Systematic searches were performed using PSI-Blast program on NCBI to identify sorghum ABC transporters. The identified proteins were subjected to phylogenetic and domain topology analyses and were classified and named according to the Human Genome Organisation (HUGO) system of classification and unified plant nomenclatural system. As part of the survey, the subcellular location, the presence of signal peptide and physicochemical parameters were determined.

β-lactam antibiotics represented the oldest class of antibiotics used in the treatment of infections in a human being, livestock, and aquaculture. Drugs residues in the edible tissues or foodstuffs of animal pose a potential threat to human health. At present, extensive antibiotic-resistant strains are now being detected and the development of antibiotic-resistant strains of epidemic and zoonotic pathogens is a major concern. Therefore, the purpose of this study was to estimate the extent of β-lactam antibiotics-HSA/BSA conjugations via three conjugation methods by using high-performance liquid chromatography (HPLC) with ultraviolet (UV) detector. We wish that the technique will be applied to preliminarily detect the residues of β-lactam antibiotics may persist in edible tissues or foodstuffs in the livestock and aquaculture farms in clinical.

A 39-years-old Caucasian man presented with the complaint of gingiva bleeding during tooth brushing. Additionally, generalised intrinsic blue-brown discoloration or hyperpigmentation of the gingiva was noticed. Upon request to report each alteration of life style and food and drink consumption during the last months, the patient reported weekly subcutaneous self-injections with Melanotan® during the last six months in order to realize a cosmetically attractive brown skin color. Melanotan I®, with the generic name afamelanotide, is thought to mimic the effects of endogenous α-melanocyte stimulating hormone, leading to increased cutaneous pigmentation. It was suspected that this drug also has the adverse effect of up-regulation of brown-black eumelanin synthesis in the oral soft tissues. Several cutaneous adverse effects of afamelanotide have been reported in the scientific literature, but no previous reports could be found on discoloration of the oral soft tissues.

Along with the rapid development of genetic engineering technology and antibody engineering technology, the humanized monoclonal antibody has been rapidly developed and gradually replaces the rat sourced monoclonal antibody. In this paper, we establish two new logarithmically completely monotonic functions involving the real-valued special functions according to two preferred interaction geometries, necessary and sufficient conditions are presented for one of them to be logarithmically completely monotonic. As a consequence, a sharp inequality involving the real-valued special functions is deduced to solve the problems of genetically engineered antibody.

The therapeutic failure rate of eradication therapy for Helicobacter pylori (Hp) is increasing due to bacterial resistance; tobacco smoking can increase such a rate even more. We explored the role of adding moxifloxacin to the standard sequential eradication therapy for Hp in decreasing the therapeutic failure rate among the tobacco smokers.

Hypopigmentation syndromes represent a readily distinguished group of diseases. Pigment dilution may involve skin, hair and iris, and is generally manifested at birth. Genetic defects of melanin biosynthesis are inherited as autosomal recessive. Griscelli syndrome is a rare autosomal recessive disorder characterised by partial albinism with or without neurological/immunological abnormalities. We report a nine year old child with Griscelli Syndrome type II with Hemophagocytic Lymphohistiocytosis.