Recent Articles

Cutaneous metastases from abdominal malignancies are rare and have been reported in less than 5% of patients [1]. Furthermore, metastases in patients suffering from colorectal neoplasia are even rarer entity. Tan et al, among 2538 of the new cases of colorectal cancer over the period of 6 years, reported only 3 cases (0.1%) with cutaneous deposits [1]. Presentation varies from cutaneous or subcutaneous small nodules, rash or large fungating lesions [1-4]. Inevitably, their presence implies the disease progression, and poor prognosis with the reported survival between 1 to 34 months [2,3,5].

Chronophysiology is an evolutionary multiscience that enables animals including humans to cope with the fluctuating environment. Timing of food intake has been discovered to orchestrate postprandial circadian rhythms of nutrient ingestion, digestion, transport, and metabolism. As such, chrono-orchestration of food intake regulates appetite and eating rate after Chrononutritional physiology is a major unnoticed healthy science that, in light of realistic modeling and understanding of voluntary feed intake in food-producing ruminant models, offers practical perceptions towards establishing health-improving feasible nutritional programs and regimens.

Cardiopulmonary interaction plays an essential role in critically ill pediatric patients. Accurate assessment of cardiac output and myocardial function has been considered vital in the successful treatment of any such patients. There are several techniques for monitoring cardiac output in seriously ill patients. The use of transpulmonary thermodilution technique for cardiac output measurements via in-dwelling pulmonary arterial catheter is considered one of the most reliable methods of hemodynamic monitoring in paediatric patients.

An examination experiment has been carried out to investigate whether fingerprint powder and lifting technique can recover and transfer latent fingerprints from human skin surfaces of dead bodies. For recovery Swedish Black powder and for transfer White Fingerprint Gelatine were used.

Longer duration of residence among immigrants to the United States, a proxy measure of acculturation, has been associated with higher subclinical atherosclerosis. South Asian immigrants are the second fastest growing immigrant group in the U.S. but little is known about the effects of acculturation with atherosclerosis in this high cardiovascular risk population.

In this report, we present a case of dermatophytosis in a dog seropositive for Ehrlichia spp.Mild annular skin lesions observed on initial presentation persisted and became worse during the course of antibiotic therapy. Microscopic examination of the fungal culture of skin scrapings revealed infection with Microsporum gypseum. The patient fully recovered following treatment with topical 1% clotrimazole and antifungal shampoo.

Human origin determination is an important aspect of blood grouping analysis in forensic science laboratories. In the present study, protein extractants like gel buffer, ammonia and saline employed for origin determination were evaluated and compared qualitatively and quantitatively for their role in the extraction of proteins from dried blood stained materials of human origin at regular time intervals.

It is common to detect microfilariae in various cytological preparations, however there are very few case reports describing microfilariae in bone marrow aspirates. It is rarer to get bone marrow failure secondary to microfilaria in bone marrow. We report here a patient from Bihar, presented to us with prolonged fever and pancytopenia, bone marrow aspirate showed microfilaria. Treatment with DEC and albendazole resulted in prompt recovery.

Harsh sentences have resulted in many prisoners being elderly at the time of their release. However, the longer individuals have been incarcerated and the older they are, the more difficult it may be for them to re-enter free society. We developed a reintegration program to promote their successful adjustment to society and to prevent their reoffending, and evaluated its effectiveness. Participants were 25 older prisoners in Japan; all were homeless and more than 65 years old.

Novel oral anticoagulants may be effective and safe alternatives to conventional treatment for left ventricular (LV) mural thrombus. A case of left ventricular mural thrombus successfully treated with dabigatran etixelate is described, and the rationale for undertaking further systematic evaluation of novel anticoagulants for this indication discussed.

Streptococcus pneumoniae is a leading cause of meningitis. Although rates of bacterial meningitis have decreased after pneumococcal conjugate vaccine introduction, pneumococcal meningitis has not been eliminated. In this case series, we describe the presentation, serotypes, and outcomes of 11 children with pneumococcal meningitis at a tertiary children’s hospital after the 13-valent pneumococcal conjugate vaccine (PCV13) was introduced, from 2011-2013. The median age of children with meningitis was 7 years. The majority of the isolates (82%) were susceptible to penicillin. Most isolates (73%) were serotyped and there was no evidence of disease caused by serotypes contained in PCV7

Ion channels are pore-forming structures across lipid bilayers that control the movement of selected ions into and out of cells along their electro-chemical gradients. The flow of ions through the channels establish voltage and ion concentration gradients across the lipid bilayer that are essential to cell survival. It follows that ion channels were components of the earliest cells and existed before the emergence of polypeptides of sufficient complexity to control transbilayer ion movement.

Vegetarian diets are associated with reduced risk for diseases such as diabetes and cardiovascular disease. We aimed to determine the nutritional adequacy of usual food intake in a cohort of young vegetarians and omnivores who regularly exercise.

Basal cell carcinoma is the most frequent malignant tumor of the skin, and the most common carcinoma found in some countries. The main clinical subtypes of BCC are nodular, superficial, pigmented and morpheaform. The majority of the lesions appear on the head and neck, with a particular predilection on the upper central part of the face.

We set out to determine the possibility of radiographically evaluating the degree of marginal bone loss in humans after functional loading of implants at sites of guided bone regeneration (GBR) with autogenous tooth-based bone graft (ATBBG) material (AutoBT®, Korea Tooth Bank, Seoul, Korea).

This case report describes the diagnosis and management of a large mesenteric cyst in a 55 year old lady who presented with abdominal distension & with mass in the left upper quadrant. Mesenteric cysts are rare, benign, abdominal tumors to which

In this paper we report our results on the green synthesis of nontoxic, stable, and small size gold nanoparticle suspensions. We used the single and two-beam laser to ablate a gold target submerged in deionized water containing chitosan or starch as the stabilizing agent. Since both chitosan and starch are biodegradable and biocompatible, use of these natural polymers for gold nanoparticle protection and stabilization does not introduce any environmental toxicity or biological hazards.

The DNA mismatch repair (MMR) system is necessary for the maintenance of genomic stability. The MMR system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops (IDLs) and heterologies generated during DNA replication and recombination.

Seventeen alpha hydroxyprogesterone caproate (17-OHPC) is the only FDA-approved drug labeled for prevention of preterm delivery. This drug is also available as a compounded product from licensed compounding pharmacies. This article reviews the FDA approval history and pharmacy compounding quality control data of 17-OHPC, as well as briefly discusses possible future pharmaceutical development strategies for 17-OHPC.

Cholesterol is an amphipathic sterol compound that exerts both structural and physiological tasks in the plasma membrane of all eukaryotic cells. The planar and rigid structure of this molecule regulates the fluidity of the phospholipid bilayer and its permeability to solutes and ions.