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Articles Related to Cancer

Correlation between Overall Survival and Quality of Life in Patients with Esophageal Cancer: A Comparison between Radiation and Chemoradiation

Desirable treatment options for inoperable esophageal cancer considering not only overall survival (OS) but also quality of life (QOL) during the entire clinical course remain unclear. We evaluated OS and QOL during the clinical course of patients with inoperable esophageal cancer undergoing chemoradiation or radiation. Forty-four patients with inoperable esophageal cancer between 2015 and 2020 were included in this retrospective study.
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Late Benign Gastrobronchial Fistula after Esophagectomy for Esophageal Cancer: A Case Report

Benign gastrobronchial fistula (GBF) is extremely rare but highly fatal complication of esophagectomy for upper gastrointestinal system cancers. We present a benign GBF after three years esophagectomy for esophageal cancer with presenting recurrent pneumonia. We choose wedge bronchoplasty without lobectomy and primary repair of gastric conduit as an approach.
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Impact of the Prognostic Nutritional Index on Quality of Life of Terminal Cancer Patients

When cancer is terminal and cancer-directed therapy has no value, the goal of treatment is to improve the quality of life (QoL). The current work proposed to assess the prognostic nutritional index (PNI) on QoL in patients with terminal cancer
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How Nurse Education Impacts Her Career?

A great proportion of healthcare services need high-quality medication and nursery. For high-quality nursery needs best nurses and their education. Gradually, different types of nursery education systems can impact their life and career. In the future, more parameters can be used for judging the quality and promotion of nurses. This editorial addresses different educational efforts for their progresses in medical knowledge promotion, technical capability improvement and salary promotion.
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Sysmex UD-10 should Accompany UF-5000 in Managing Atypical Cells in Urine

Sysmex UF-4000/5000 uses fluorescence flow cytometry technology and hydrodynamic focusing for urine sediment analysis, where particles are stained by specific fluorochromes for nucleic acids and surface structures and then sent through the semi-conductor laser beam. Atypical cells show side fluorescence and scattered light properties indicating their enlarged nuclei and increased nucleus/ cytoplasm ratio
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Exhaled Volatile Organic Compounds in Patients with a Medical History of Cancer/Dysplasia

Exhaled Volatile Organic Compounds (E-VOCs) have been associated with cancer and may help to early detection or even identify pre-cancerous status.
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Application of the Posterior Approach Technique in Laparoscopic Radical Hysterectomy for Cervical Cancer

The aim of this study was to compare and determine the feasibility, surgical outcomes, intraoperative and postoperative complications of the use of the posterior approach technique in the laparoscopic radical hysterectomy (LRH) to the conventional laparoscopic radical hysterectomy in patients with cervical cancer.
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Cranial Vault Tumor Revealing Metastatic Thyroid Carcinoma

Distant metastases from follicular thyroid carcinoma are not uncommon, but bone localization in the cranial vault is extremely rare. Although these metastases have a poor prognosis, early diagnosis and appropriate treatment can improve quality of life. We report a case of follicular thyroid carcinoma revealed by a metastasis of the cranial vault initially diagnosed as meningioma.
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Oral Carcinoma in Young-Clinico-Pathological Profile and Survival Outcomes in a North Indian Population

To study the prevalence, clinico-pathological profile and survival outcome of oral squamous cell carcinoma in young patients (<40 years).
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Multiple Sclerosis Disease Modifying Therapy and Cancer risks

Multiple sclerosis (MS) is a chronic inflammatory condition not commonly associated with cancer. Although since 1993 with the introduction of disease modifying therapies (DMTs), changing the natural history of the disease, cancer risk appears associated with some of these new therapies. We present the most common risks associated with each DMTs.
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Drug Therapy Problems and Clinical Outcomes Among Patients with Human Epidermal Growth Factor Receptor 2 (HER2) Positive Breast Cancer on Trastuzumab-Based Therapy in a Kenyan Tertiary Health Facility

Breast cancer ranks first among the most commonly diagnosed cancers in Kenyan females and globally. Treatment is challenging because it is a heterogeneous disease with several subtypes. There has been a significant change in the treatment of Human Epidermal Growth Factor Receptor 2 (HER2) positive breast cancer subtypes following the introduction and widespread use of HER2 targeted therapies.
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Clinicopathological and Prognostic Value of Plasmacytoid subtype in Bladder Cancer: A Systematic Review and Meta-Analysis

The World Health Organization, in 2004, published a new classification that recognizes different histological variants (HV) of urothelial carcinomas
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A Screening Study of Cervical Cancer Using Pap Smear Test in Outpatient Clinic of Must University Hospital

Despite the well-established importance of early cervical cancer detection, there are no clear data about the prevalence of cervical intraepithelial lesions among Egyptian population due to lack of screening programs. Thus, we conducted this study in order to assess the prevalence of inflammatory, premalignant and malignant cervical lesions among Egyptian population using Pap smear test.
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Cost-Effectiveness and Budget Impact Analysis of Recombinant Tumor Necrosis Factor-Thymosin Alpha 1 in a Complex Treatment of Metastatic Breast Cancer

Recombinant tumor necrosis factor -thymosin alpha 1 (TNF-T) has been used in Russian oncological practice for a number of years.
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Predictive Value of ERCC1 Expression on Treatment Response to Cisplatin-Based Regimens in Small Cell Lung Cancer: A Retrospective Analysis

We aimed to determine whether the excision repair cross-complementation group 1 (ERCC1) expression predicts response to cisplatin-based chemotherapy in patients with small cell lung cancer (SCLC). This was a retrospective study, in which hospital files of 31 patients (29 males, 2 females; mean age, 62.26±7.71 years) were reviewed. All patients were treated with etoposide+cisplatin. The lung biopsy and mediastinal lymph node samples were applied anti-human monoclonal antibodies against ERCC1: immunohistochemical staining was considered positive if 25-100% of the cells showed nuclear staining, and negative if less than 25% of the cells showed negative or slight staining. Response to treatment was evaluated as regression (complete or partial response), progressive disease, or stable disease. Of the patients, 18 (58.1%) had limited-stage, and 13 (41.9%) had extensive-stage SCLC. Median follow-up duration was 15 months (range: 1-60 months). ERCC1 staining was positive in 9 of 31 patients (29.0%). In 12 patients (38.7%), tumor regression (complete or partial response) was obtained after chemotherapy. Tumor regression rate was higher in ERCC1 positive patients than those with negative ERCC1 expression (66.7% vs. 27.3%, p=0.036). In conclusion, high expression of ERCC1 was associated with higher response rate to cisplatin-based regimens in patients with SCLC.
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Editorial Board Members Related to Cancer

Fathinul Fikri Ahmad Saad

Senior lecturer
Centre for Diagnostic Nuclear Imaging
University Putra Malaysia
Malaysia

Marc Poirot

Research Director at INSERM
Cancer Research Center of Toulouse
University of Toulouse
France

Diego Andrés Chiappetta

Associate Professor
Department of Pharmaceutical Technology
University of Buenos Aires
Argentina

Mario P. S. Chin

Assistant Professor
Department of Microbiology and Immunology
Temple University
United States

ARA ANTONYAN

Associate Professor
Department of Biophysics
Yerevan State University
Armenia

Xiaoming Yang

Professor
Department of Radiology
University of Washington School of Medicine
United States

VEENA N. RAO

Professor
Department of Obstetrics and Gynecology
Morehouse School of Medicine
Georgia Cancer Center for excellence
United States

Tao Liu

Children's Cancer Institute
University of New South Wales
Australia

Michael Gibson

Associate Professor
Department of Medicine
Case Western Reserve University
United States

Mridula Chopra

Senior Lecturer
School of Pharmacy and Biomedical Sciences
University of Portsmouth
United Kingdom
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