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Articles Related to EAC

Detection of a Rheumatic Factor (RF,) Anti- Cyclic Citrullinated Peptides (Anti CCP) Antibodies and C- Reactive Protein (CRP) in Diagnosis and Prognosis of Rheumatoid Arthritis

Introduction: Rheumatoid arthritis ( RA)is an autoimmune and inflammatory disease. It is characterized by arthrosynovitis with resultant joint destruction . So, an early clinical diagnosis along with simple serological tests like anti CCP antibodies, C –reactive protein ( CRP) and Rheumatoid factor (RF) play an important role .An attempt was made to study and compare these parameters in OPD and IPD RA patients in our hospital setup, VMMC and Safdarjung Hospital , New Delhi. Aims and Objectives: To study the role of RF , Anti-CCP antibodies and CRP in early detection and prognosis of Rheu- matoid arthritis. Materials and Methods: A Total of 440 samples were studied from January 2018 to December 2020 (3years). Correlation between Rheumatoid factor(RF) ,anti CCP antibodies and CRP in suspected RA patients from various departments like PMR , Orthopaedics , Medicine, Obstetrics and Gynaecology and Paediatrics was attempted. RF and CRP was performed using latex agglutination test and anti CCP antibody by ELISA. Results and Conclusion: Of 440 samples tested, all the factors were positive in 87 patients . Anti CCP and RF alone was seen in 32 patients. RF and CRP positive in 49 patients, RF alone in 22 patients. In 250 patients all the tests were negative. So, Anti CCP along with RF and CRP showed a better positive predictive value in patients of Rheumatoid arthritis. But positivity of these parameters even in patients who lack sign and symptoms also aids in better diagnosis, treatment and prognosis.
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Potential COVID-19 Therapeutics: A Perspective on Pharmacological Properties and Safety

There are no guidelines for pharmacological treatment of COVID-19 disease, but several drugs are being tested every day in search of an optimal therapeutic strategy. The drugs that have been tested, so far, include some antiviral drugs such as danoprevir, favipiravir, darunavir, nelfinavir, remdesivir, umifenovir and the combination lopinavir/ritonavir. Others are drugs targeting inflammatory mediators such as meplazumab, siltuximab, tocilizumab, azithromycin and corticosteroids. Also included in this array of tested drugs are those with pleiotropic actions against SARS-CoV-2 infection like chloroquine/hydroxychloroquine, ivermectin and nitazoxanide, postulated as inhibitors of several phases of virus life cycle. Upon diagnosis of SARS-CoV-2 infection, it is pertinent to embark on a treatment approach based on potential antiviral options, adequately managed under proper medical situation. We suggest that, in addition to the antiviral option efforts, drugs targeting inflammatory mediators should be considered.
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Study on Deactivation Mechanism of Catalytic Oxidation of Formaldehyde Over CexZr1-xOy

Formaldehyde (HCHO) pollution was eliminated by catalyst effectively. The CexZr1-xOy catalyst was prepared by coprecipitate method, and its performance of HCHO removal was investigated. The results showed that the HCHO removal rate decreased from 100% to 60.88% when the reaction time was from 24h to 48h.In order to study the deactivation mechanism of the CexZr1-xOy catalyst,N2 adsorption and desorption, SEM, EDS, FT-IR, XRD and XPS were used to characterize CexZr1-xOy after different reaction times. Characterization results showed that the pore structure of CexZr1-xOy did not change significantly with the extension of reaction time, and C6H9CeO6 and Ce(CO3)2 increased gradually, while the active component Ce4+ decreased sharply. Therefore, the production and deposition of products are the main reasons for the deactivation of the CexZr1-xOy catalyst. The catalytic performance of regenerated CexZr1-xOy catalyst was tested for 24h, and the results showed that it almost recovered to fresh CexZr1-xOy catalyst. This provides a reference for the preparation of efficient catalyst for formaldehyde removal.
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A Case Report of Peripheral Giant Cell Granuloma

Peripheral giant cell granuloma (PGCG) is a rarely seen benign lesion at soft oral tissue. In this report, the patient had a history of central giant cell granuloma at the left mandibular posterior region. The lesion was excised two years ago. Patient was consulted to our hospital for soft tissue growth at right maxillary anterior region. Excisional biopsy was planned and the lesion was examined histopathologically. Giant cell reparative granuloma was described and routine examination was advised to the patient
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Healthy Living and Lifestyle with Prophet Teaching

The aim of this review is to highlight the Islamic teachings that go beyond the spiritual and religious life of the Muslim, as it provides a healthy outline for daily life.
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Study on Prescribing Pattern of Antibiotic used for Urinary Tract Infection in Tertiary Care Teaching Hospital: A Preliminary Antibiotic Stewardship Programme

Urinary tract infection is defined as the presence of microorganism in the urine that cannot be accounted by contamination. First line treatments for UTI are antibiotics. Antibiotic stewardship is the coordinated intervention designed to improve and measure the appropriate use of antibiotic agents, by promoting the selection of optimal antibiotic drug regimen including dosing, duration of therapy and route of administration.
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Production and Stabilization of Biomass Derived Bio-Oil using Non-Catalytic Pyrolysis Approach

Considering high demand of exploring clean and sustainable source of energy worldwide, biomass derived green bioenergy has tremendous potential. Amongst all possible ways of biomass processing to derive bio-fuels, the biomass pyrolysis is highly preferred thermochemical process that converts the biomass to bio-oil. In our present work, the noncatalytic pyrolysis of ligno-cellulosic biomass samples (sawdust, rice straw and cotton stalk) was successfully carried out using in-house developed fixed bed pyrolytic reactor.
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Rapid Hydrogenation of Toluene in a One-Pass Reactor at Ambient Temperature and Pressure on a Novel Nanostructured Super-Alloy Catalysts without Containing Noble Metals

Novel Ni-Re super-alloy catalyst system is found for rapid hydrogenation of toluene to methylcyclohexane (MCH) in a one-pass reactor under mild reaction conditions. The novel bimetallic Ni-Re alloy catalysts exhibit the remarkably enhanced activity and stability for hydrogenation of toluene by comparison with monometallic Ni catalyst. The catalytic performance of novel Ni-Re catalyst is compared with that of Pt catalysts for hydrogenation of toluene. The better activity maintenance of the Ni-Re catalysts than the Pt-based catalysts are found. The alloying effect of Ni with Re is identified by XRD and EXAFS measurements.
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Epidemiological, Clinical and Radiographic Profile of Thoracic Manifestations Associated with Sickle Cell Anemia in Adults at Teaching Hospital Yalgado Ouédraogo in Ouagadougou at Burkina Faso

Sickle cell anemia is a public health priority, but do its chest manifestations always require a chest radiography ? Our study aims to determine the epidemiological, clinical and radiographic profiles of the thoracic manifestations in the drepanocytic adult in the city of Ouagadougou (BURKINA FASO).
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Anemia Associated to Helicobacter pylori at Teaching Hospital Yalgado Ouédraogo (CHU-YO) of Ouagadougou in Burkina Faso

Infection with Helicobacter pylori(H. pylori) is implicated in iron and vitamin B12 deficiencies without any etiologies. Our prospective study conducted at the Teaching Hospital Yalgado OUEDRAOGO at OUAGADOUGOU (BURKINA FASO) aimed to find a link between H. pyloriinfection and anemia in our context. Patients and Methods:Were selected, patients with iron deficien
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Voromonas Pontica Identified by Giemsa Staining and Anti-RhopH3 Protein Reactivity

Culture characteristics, routine staining for light microscopy and feeding behavior of Voromonas pontica Cavalier-Smith (American Type Culture Collection, ATCC 50640), a predatory free-living marine colpodellid, was investigated
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Anaemia Phenotypes in Highly Active Antiretroviral Treatment Defaulting Adults at the Comprehensive Care Clinic at the Siaya County Teaching and Referral Hospital

Anaemia is a major cause of morbidity and mortality among people living with human immunodeficiency virus (HIV) infection. While adherence to antiretroviral treatment (ART) reduces the incidence of anaemia, non-adherence (defaulting) to ART is associated with a number of haematologic derangements including anaemia. However, the mechanisms and predictors of anaemia have not been examined among ART defaulters in western Kenya. This study, therefore, aimed at evaluating the anaemia prevalence and classification of the anaemia based on haemoglobin (Hb) concentrations and erythrocyte morphology as well as suppression of erythropoiesis in ART-defaulting adults at a comprehensive care clinic in western Kenya.
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Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Twin Sisters after Ibuprofen Administration. New Insights in Pathogenesis and Literature Review

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are closely-related, severe, acute life-threatening, drug-induced skin and mucosal disorders with a high mortality rate or long-term damages. These medical conditions are considered a delayed, typeIV hypersensitivity reaction and can be triggered by drugs, infections and malignancies.
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Effects of Transfer Factor Supplementation on Immune Reactions in Mice

Colostrum-derived transfer factors are among the highest potential natural immunostimulatory food supplements. In our study, we evaluated the possible effects of supplementation with various compositions that included transfer factors in phagocytosis, TNF-α and IL-2 secretion, antibody formation and NK cells activity. We found significant improvements of all these immune reactions after 7 days of supplementation.
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Development of a Continuous Fluidic Reactor for the Photocatalytic Treatment of Liquid Effluents

The present study aims at developing a photocatalytic mesofluidic reactor for the continuous treatment of liquid effluents.
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Preparation of Large Area Anodic Alumina Membranes and their Application to Thin Film Fuel Cell

The design of an electrochemical reactor for the preparation of self-supported comparatively thin (up to 10 μm) and large area (up to 50 cm2) anodic alumina membranes is described allowing growth of porous alumina at high applied potential (up to 150 V) without burning.
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Editorial Board Members Related to EAC

INTAN HAKIMAH ISMAIL

Associate Professor
Department of Paediatrics
Faculty of Medicine and Health Sciences (FMHS)
University Putra Malaysia
Malaysia

Michael Zhuo Wang

Assistant Professor
Department of Pharmaceutical Chemistry
The University of Kansas
United States

Judyth L. Twigg

Professor
Department of Political Science
Virginia Commonwealth University
United States

Carla Cicala

Professor
Department of Pharmacy
University of Naples Federico II
Italy

Sherman Wessel Jack

Professor
Department of Pathobiology
Mississippi State University
United States

Yoshiya Toyoda

Professor
Cardiothoracic Surgery
Temple University School of Medicine
United States

Agnieszka Alicja Karczmarczyk

Assistant professor
Faculty of Civil and Environmental Engineering
Warsaw University of Life Sciences
Poland

SANJEEV KUMAR SINGH

Professor
Department of Bioinformatics
Alagappa University
India

Maged A. Tanios

Associate Clinical Professor of Medicine
David Geffen School of Medicine
UCLA
USA

Peter L. Bordi

Associate Professor
School of Hospitality Management
Pennsylvania State University
United States
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