Articles Related to GIF
A Review on Antioxidant, Anti-Inflammatory and Gastroprotective Abilities of Mango (Magnifera indica) Leaf Extract and Mangiferin
Mango (Mangifera indica Linn.) trees have been cultivated and grown in Southern and Eastern India for thousands of years and have slowly spread all over the world. For over 4,000 years various parts of mango trees including leaf and fruit pulp have been extensively used in Ayurvedic and Unani medicines.
Methylmalonic Acidemia and Megaloblastic Anemia due to Congenital Intrinsic Factor Deficiency
Causes of vitamin B12 deficiency in children include decreased intake, abnormal absorption, and inborn errors of B12 transport and metabolism. Rare causes of abnormal cobalamin absorption include Imerslund-Grasbeck syndrome (IGS) and intrinsic factor deficiency (IFD). IGS and IFD are caused by defects in the genes CUBN, AMN, and GIF. We describe a 2 year old male who presented with severe megaloblastic anemia and methylmalonic acidemia. He was found to have a GIF heterozygous mutation c.79+1G>A associated with congenital gastric intrinsic factor deficiency and a novel variant c.960C>A in trans position.
Investigating the Double-Peak Phenomenon in Oral Pharmacokinetics of Eurycoma Longifolia quassinoids in Lipid-Based Solid Dispersion
13α(21)-Epoxyeurycomanone (EP) and eurycomanone (EN), the polar quassinoids of Eurycoma longifolia extract (TAF2) formulated as a lipid-based solid dispersion (TAF2-SD) to increase sperm count for oligospermic infertility, displayed improvement of oral pharmacokinetics and bioavailability in rats over the non-formulated TAF2 extract.
Editorial Board Members Related to GIF
Qingzhong Kong
Associate Professor
Department of Pathology
Case Western Reserve University
United States
Department of Pathology
Case Western Reserve University
United States
Wen-Quan Zou
Associate Professor
Departments of Pathology and Neurology
Case Western Reserve University School of Medicine
United States
Departments of Pathology and Neurology
Case Western Reserve University School of Medicine
United States