Articles Related to Gastrointestinal

Occasional constipation is associated with infrequent bowel movement and difficulty in passing stools without any obvious symptoms. Ginger has been used traditionally to manage various gastric conditions like constipation, dyspepsia, belching, bloating, epigastric discomfort, indigestion, nausea, and vomiting. The current study evaluated the effects of a standardized Ginger extract (GE) on objective and subjective markers of occasional constipation in a randomized, double-blind, parallel, placebo-controlled design

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Regular whole-flock treatments and long-term repeated use of similar anthelmintics has led to the development of anthelmintic resistance and widespread epidemic of sheep nematodiasis. The current work was carried out to understand the prevalence of gastrointestinal nematodes in Ordos fine-wool sheep and to evaluate the efficacy of currently used anthelmintics.

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100% fruit juice (e.g., orange juice [OJ]) in 237 mL doses is considered 1 serving of fruit and generally recommended as a part of a healthy diet.

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Congenital malformations can go unnoticed and have an impact on morbidity and mortality in early stages of life being a cause of infant death in some countries [1]. Malformations of the gastrointestinal tract occupy the second place among congenital abnormalities [2]. Along with them, the enteric duplication cyst is an infrequent anomaly difficult to diagnose specially for a non-specialist physician that is not use to attend this kind of pathologies or in hospitals where patients with this entities are infrequent. We present the case of a 5-month-old patient who underwent intestinal resection due to enteric duplication cyst.

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This study aimed to determine whether a relationship exists between gingival stimulation and the levels of leptin, ghrelin, insulin and glucose, which are important regulators of energy homeostasis. Blood samples for ghrelin, leptin, glucose and insulin were taken from 15 male volunteers (mean age 25.5±2.3 years; mean body mass index 24.4±2.79 kg/m2), who did not brush their teeth for one day, after a 12 h-long overnight fasting and before standard breakfast (0 min) and thereafter at 30, 60, 120 and 180 min after breakfast. After toothbrushing after dinner and after a 12 h-long overnight fasting, blood samples were taken again before standard breakfast (0 min) and then after at the same time points following tooth brushing.A significant reduction was found in the leptin levels measured at 0, 30, 60, 120 and 180 min after tooth brushing (p < 0.005). The ghrelin levels also declined at these time points but were significant at 0, 30 and 120 min (p < 0.05). Despite the reduced insulin levels at 120 and 180 min after tooth brushing (p < 0.05), no significant change was observed in the glucose levels.

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Extrapleural solitary fibrous tumors (SFT) and gastrointestinal stromal tumors (GISTs) are similar morphologically and on imaging studies. We report a case of a patient with a giant pelvic tumor, which was difficult to be diagnosed. A 71-year-old male presented to our hospital with a complaint of urinary retention. A radiological examination showed a giant pelvic tumor mass, which ventrally compressed the urinary bladder and rectum, and was supplied by vascular flow from the right internal iliac artery. The resected specimen was 15 × 10 cm, elastic soft, and solid pale yellow in color. Because the tumor was histologically composed of spindle-shaped cells and was CD34 positive, cytokeratin negative, epithelial membrane antigens negative and KIT negative, we first thought the tumor was a KIT-negative GIST.

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Wilkie’s Syndrome (WS) was described in 1927 and its physiopathology is related to the formation of an abnormal acute aortomesenteric angle measuring between 7o and 22o. It leads to digestive symptoms due to external compression of mesentery artery against the third portion of duodenum. This is a case of WS in a young, tall and slim male patient. Three months before, he began postprandial vomiting, abdominal pain, hyporexia and weight loss. The diagnostis was made by an upper gastrointestinal series with barium contrast and confirmed by Laparotomy. Duodenojejunostomy is a well-known technique and it was successfully performed in this case.

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Corrosive injuries of the Upper gastrointestinal tract (UGIT) are common in developing countries mostly mortality and morbidity is high in India due to suicidal attempts. In this case series, a 17 years old female and 51 year old male subject intentionally self-harmed by ingesting toilet cleaner containing higher amounts of hydrochloric acid and presented to the emergency department of tertiary care hospital and the different aspects of the case are discussed in detail in this paper.

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Parasitic gastroenteritis caused by gastrointestinal nematodes (GIN) continues to be a major constraint against profitable small ruminant production. The increasing prevalence and severity of anthelmintic-resistant nematodes in many parts of the world has led to a search for non-chemical control options.

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A simple and sensitive two-step reversed-phase HPLC method was developed and validated for determining amphotericin B, paracetamol and sulfapyridine in rat plasma using piroxicam as internal standard.

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Eugenol (EU) and ibuprofene (IBU) were covalently bound to a bi-functionalized PEG, used as molecular carrier of drugs and the release kinetics of the two bioactive molecules was studied in vitro in buffer solution at pH 7.4, in simulated gastric fluid and in mouse plasma.

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Guillain-barré syndrome (G.B. Syndrome) is an acute inflammatory poly-radiculoneuropathy characterized by weakness and areflexia typically following viral infection, vaccination, and rarely surgery. Acute Inflammatory Demyelinating Poly-radiculoneuropathy is the most common subtype of G.B. Syndrome. Although post-operative G.B. syndrome is a rare entity, there are few case reports of G.B. syndrome after gastric surgery. But there have been no reported case scenarios of atypical variety of this neurologic entity following hepato billiary surgery. Hence our objective is to put forward this message to the readers.

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A seventy five year male presented with acute onset right foot pain and swelling. Plain imaging revealed a lytic area in the medial and middle cuneiform bones of the right foot. Background history of resected pancreatic cancer and current presentation were consistent early diffuse disease recurrence of a pancreatic primary tumour. The presenting feature in this case was of symptomatic acrometastases, that is, metastases to the feet.

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Recently, transdermal drug delivery system (TDDS) has become a more and more important approach to administering drugs. Based on its advantages, which are not achievable by other modes of administration, many researchers are dedicated to the study of it, and have made great progress. Although the skin offers a painless interface for systemic drug delivery, it also presents limitations which are mainly caused by the stratum corneum.

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The Health Improvement Network (THIN) provided data from UK General Practitioners (GPs) for 144 pregnant women who were prescribed zanamivir and 144 age- and date-matched untreated comparators with no recorded diagnosis of influenza. Groups were assessed for baseline characteristics, treatment-emergent diagnoses in the mother, pregnancy outcomes and congenital malformations diagnosed in the offspring within 28 days of birth.

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