Acquired heart diseases such as myocarditis, cardiomyopathies and rheumatic heart diseases are important non-communicable diseases responsible for morbidity and mortality in children.
Mitogen-Activated Protein Kinase (MAPK) pathway is a signal transduction pathway that functions in a wide range of physiological and pathophysiological cellular events including cell proliferation, differentiation, apoptosis, migration, inflammation, metabolic disorders and diseases.