Articles Related to Low birth weight
The Efficacy and Safety of Prophylactic Fluconazole Prevent Invasive Fungal Infection in Preterm Very Low Birth Weight Infants: An Update Meta-analysis
We identified 8 eligible trials that enrolled 1392 infants. There was significant effect of prophylactic fluconazole on fungal colonization (RR, 0.31, 95%C1:-0.24 to 0.41; P<0.00001). Effect of prophylactic fluconazole on IFI in VLBW infants: RR: 0.42(95%CI 0.23 to 0.76; P=0.004.). However, prophylactic fluconazole did not reduce mortality in VLBW infants (RR 0.76, 95% CI 0.58 to 1.01; P = 0.06). Studies did not report significant adverse reactions.
Neonatal Endotracheal Tubes and Prevention of Bronchial Intubation
Right main stem bronchial intubation (RMSBI) causes morbidity during neonatal assisted ventilation. Over-distention of the right middle and/or lower lobes of the lung and under-ventilation and/or atelectasis of the remaining lung are the major complications of RMSBI [1,2]. Complications of RMSBI include a) over-inflation of a pulmonary lobe (lobar emphysema), b) pulmonary interstitial emphysema, c) pneumothorax, and/or d) pneumomediastinum [3]. In very preterm infants, pneumothorax correlates with the pathophysiology of intraventricular hemorrhage [4].
