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Articles Related to Microbiota

The Impact of Seasonal Changes on Growth Performance, Rumen Fermentation, and Rumen Microbiota Structure of Yaks: An Analysis Using the Supplemented 2.5kg Concentrate Level as an Example

The study investigated the effects of supplementing the same level of concentrate in different seasons on the growth performance, rumen fermentation, serum biochemical index, and rumen microflora changes in yaks, to provide guidance on accurate feeding of yaks in cold and warm seasons. 12 healthy yaks weighing (124.21±15.64) kg were selected for the experiment, with a warm season group from August to October and a Cold season supplemental feeding group from October to December. The results showed that the mean daily gain was significantly higher in the warm season grazing group than in the cold season grazing group (p<0.05). Rumen fermentation, serum biochemical index, and rumen microflora changes also varied significantly between the two groups (p<0.05).
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Efficacy of Standardized Ginger Extract in Subjects with Occasional Constipation: A Randomized, Double-Blind, Parallel, Placebo-Controlled Study

Occasional constipation is associated with infrequent bowel movement and difficulty in passing stools without any obvious symptoms. Ginger has been used traditionally to manage various gastric conditions like constipation, dyspepsia, belching, bloating, epigastric discomfort, indigestion, nausea, and vomiting. The current study evaluated the effects of a standardized Ginger extract (GE) on objective and subjective markers of occasional constipation in a randomized, double-blind, parallel, placebo-controlled design
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Effects of Enterotoxigenic Escherichia coli on haematological parameters, immunity, gut microbiota profile and metabolites in weaned Ningxiang piglets

The purpose of this study was to clarify the response of Ningxiang pig against pathogenic enterotoxigenic Escherichia coli (ETEC) during the weaning period. Sixteen weaned Ningxiang pigs, were selected from one litter at 28 days and randomly allocated into two groups, with or without oral administration of ETEC (109 colony forming units/piglet/d) for two consecutive days. Blood and intestinal samples were collected after sacrifice to investigate the influence for systemic and gastrointestinal tract influences
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Anti-Infectives do not Impact Treatment Response to Immune Checkpoint Inhibitors: a Single Center Retrospective Analysis

Immune-checkpoint inhibitors (ICI) have provided groundbreaking advancements for a variety of malignancies. It has been of recent interest to identify predictive indicators of response to improve cancer management using immunotherapy. The intestinal microbiome has been recognized as a potential predictor of ICI anti- tumor activity. Antibiotics reduce diversity the overall composition of the gut microbiota, with effects seen as quickly as in a single day. Post-antibiotic dysbiosis recovery varies depending on type and duration of exposure. Preclinical studies in mice with advanced cancer treated with broad spectrum antibiotics have been associated with resistance to ICI treatment.
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Biomarkers of Microbial Dysbiosis as Causative Agent of Acute Diarrhea in Dogs

Dysbiosis is microbial imbalance and mostly common in gastrointestinal tract [1]. There is a significant different of microbial communities in diarrheic cases more than healthy dogs’ comparison of gender & clinical signs. Clostridium species is mostly commonly genus found infectious animal cases of diarrhea and moreover in dog in other hand unclassified genus of Ruminococcaceae Bacteroidetes and Faecali bacterium were isolated. The microbiome functional gene content of (PICRUSt) with elevation gastric enzymes & increase titers infra structural proteins in acute diarrhea. Studies and data for dysbiosis with different intestinal disorders in dog associated with acute diarrhea or chronic is very limited. Current study to evaluate microbial dysbiosis. The fecal microbiome, characterized by 655 pyrosequencing of the different genes, AU/CG. There was lower range of bacterial isolates from cases of acute diarrhea compared to animal variation with statistical analysis. Altered microbial imbalance in gut occur with the microbial communities for gastric infection.
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Auricular Transcutaneous Vagus Nerve Stimulation may Increase the Risk of MildCOVID-19 Infection or of Herpetic Flare: Is there a Role of Microbiota?

SARS-CoV-2 can reach the central nervous system through the vagal nerve. Microbiota may favour or prevent viral spread. Assess whether auricular transcutaneous vagus nerve stimulation (ATVNS) may favour the occurrence of mild-COVID-19 or the recurrence of herpes simplex type 1. 749 patients were included. 195 patients were recommended and comply with ATVNS. 67 patients of the ATVNS group experienced mild-COVID-19 (34.3%) versus only 28 in the not-recommended ATVNS group (525 patients; 5.3%). A similar percentage was observed in the non-compliant ATVNS group (one case for 29 patients; 3.4%) [p<0.001].
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Editorial Board Members Related to Microbiota

INTAN HAKIMAH ISMAIL

Associate Professor
Department of Paediatrics
Faculty of Medicine and Health Sciences (FMHS)
University Putra Malaysia
Malaysia

Meijun Zhu

Assistant Professor
School of Food Science
Washington State University
United States
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