Articles Related to Wistar Rat
Neurobiochemical Roles of Low Molecular Weight Antioxidants on Oxidative Stress Biomarkers and Severity of Ischemic Stroke in Wistar Rats
Purpose: To evaluate the neurobiochemical role(s) of low molecular weight (LMWA) antioxidants in the treatment of surgically- induced ischemic stroke (IS) in wistar rats.Methods: Ischemic stroke was induced in wistar rats using middle cerebral artery occlusion (MCAO). Neurological assessments were carried out using stair case, cylinder test and modified neurological severity score (mnss) methods. Low molecular weight antioxidants (vitamins C, E, α-lipoic acid, dimethyl sulfoxide and mannitol) were orally administered to the rats for two weeks in three different doses (22.5, 45 and 67.5 mg/kg).
Expression Profile of Hepatic Metallothionein-I and ATP7B, and Brain Metallothionein-III and Acetyl cholinesterase Genes in Wistar Rat Model for Non-Wilsonian Brain Copper Toxicosis
Cognitive waning due to chronic copper (Cu) intoxication in animal models is increasingly being reported; notwithstanding, information regarding molecular basis of Cu accumulation and neurobehavioral impairments remains fragmentary.
Titanium dioxide (TiO2) (<100 nm) has been widely used in the production of paints, paper, and plastics, as well as in food additives and colorants .It has been classified as biologically inert in both humans and animals. Here we studied the toxicity of TiO2 on Wister rat. Main exposure area of NPs is caudal vein of Wistar rat.