Top Links

Articles Related to cytotoxicity

Chemical Characterization, Antimicrobial-Antifungal Activity on Probiotic Micro organisms and Genotoxicity–Cytotoxicity Effects of Lamiaceae Family Essential Oils from Different Plants

Pipermint, thyme, rosemary, sage and basil species which have major characteristic specialities of Lamiaceae family, have antimicrobial activities on pathogene microorganisms. Probiotic microorganisms have valuable effects on human body and inhibition of probiotics causes many diseases. In this present study, it was aimed to determine indicate probiotic resistance against natural antimicrobial agents (as essential oils) compare to pathogenes in previous studies.
View complete article: PDF  |  Full-text

A Review on Nanoprobes for Sensing, Imaging and Disease Detection

This review focuses on imaging, visualization and detection of diseases using nanoprobes. Several currently available nanoprobes such as fluorescent nanoprobes, upconversion nanoparticle probes, supermagnetic iron oxide nanoprobes, and polymer- and liposome based nanoprobes are discussed.
View complete article: PDF  |  Full-text

Anti-GnRH Receptor Monoclonal Antibodies, First-In-Class GnRH Analog

A monoclonal antibody (Mab) designated as GHR106 was generated against the extracellular domain (N1-29 synthetic peptide) of human gonadotropin releasing hormone (GnRH) receptor. It is a first-in-class GnRH analog and can serve as a drug candidate for potential applications in the treatment of human cancers and/or fertility regulations.
View complete article: PDF  |  Full-text

Targeted Approach for Prostate Cancer Treatment: Synthesis and Characterization of Docetaxel-Loaded Perfluorocarbon Nanodroplets

The purpose of this study is to synthesize and characterize nanodroplets, loaded with docetaxel for treatment of prostate cancer under MR-guided focused ultrasound. Water insoluble docetaxel encapsulated in nanodroplets is expected to be delivered into tumors with greater efficiency while minimizing drug related systemic toxicities when used in combination with focused ultrasound. The sequence of our studies toward development and characterization of docetaxel-loaded nanodroplets is as follows. First, we developed methods for synthesis of ultrasound-responsive, docetaxel-loaded nanodroplets (Doc-nd) by a solid dispersion technique. Secondly, we characterized Doc-nd by its morphology and size distributions using a dynamic light scattering (DLS) method.
View complete article: PDF  |  Full-text


Editorial Board Members Related to cytotoxicity

A. F. M. Motiur Rahman

Associate Professor
Department of Pharmaceutical Chemistry
College of Pharmacy, King Saud University
Saudi Arabia

Ana Rita Ramalho Figueiras

Faculty of Pharmacy
University of Coimbra
Portugal
Submit Manuscript