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Articles Related to encephalopathy

Gliomatosis Cerebri: A Case Report

Background: Gliomatosis cerebri is a rare primary brain tumor that can have extensive infiltration into the brain parenchyma. It can affect any age group and often has poor clinical outcomes. Given its unique pathology, presentation and treatment can be challenging to recognize and efficaciously treat
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A Tunisian Patient with CLCN2-Related Leukoencephalopathy

CLCN2 related leukoencephalopathy (CC2L OMIM#: 615651) is a recently identified rare disorder, caused by autosomal recessive mutations in CLCN2 gene, leading to the dysfunction of its encoded CLC-2 chloride channel protein with characteristic brain MRI features of leukoencephalopathy
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Acute Confusional Syndrome in Patient with Relapsed/Refractory Multiple Myeloma

Acute confusional syndrome in a patient with multiple myeloma (MM) opens a wide range of diagnostic possibilities, from infectious diseases, endocrine metabolic disorders and drug toxicity, to more infrequent causes such as hyperviscosity syndrome, among many others.
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Hypovolemic Shock Following Subgaleal Hemorrhage with Associated Hypoxic Ischemic Encephalopathy in a Term Infant

We are reporting an infant who was born by emergency cesarean section following failed vaginal delivery. This infant was noted to be in hypovolemic shock soon after birth. He developed large subgaleal hemorrhage within 6 hours after birth with associated diffuse intravascular coagulopathy and hypoxic-ischemic encephalopathy. He required multiple transfusions of packed red blood cell, platelets transfusion, fresh frozen plasma transfusions, and a cryoprecipitate. The infant was on body cooling therapy for hypoxic ischemic encephalopathy for three days. His neurological exam at the time of discharge was unremarkable. At the time of discharge, an infant is enrolled in an early intervention program with a multi-disciplinary follow-up scheduled.
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Hepatic Dysfunction as Presenting Manifestation of Hodgkin’s lymphoma

Hepatic dysfunction is rarely the presenting feature of malignancy, however it is important to recognize early on as the quick institution of chemotherapy could potentially reverse the liver disease.
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Therapeutic Hypothermia Still Effective in Prevention of Anoxic Encephalopathy following Extended Period of Pulselessness during Cardiac Arrest

There are approximately 300,000 out-of-hospital cardiac arrests per year with less than 10% of those surviving. More than half of survivors suffer permanent neurologic deficits. Therapeutic hypothermia has proven effective at thwarting neurologic damage occurring in the 16-hour window following return of spontaneous circulation (ROSC). Despite recommendations by the American Heart Association (AHA), many cardiologists have been slow to implement therapeutic hypothermia. While many trials have discussed the relevance of initial rhythm and delay of cooling, there has been limited discussion of the efficacy of therapeutic hypothermia in the presence of extended pulselessness.
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Editorial Board Members Related to encephalopathy

Qingzhong Kong

Associate Professor
Department of Pathology
Case Western Reserve University
United States

Wen-Quan Zou

Associate Professor
Departments of Pathology and Neurology
Case Western Reserve University School of Medicine
United States
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