Articles Related to human chondrocytes
The Effect of Interleukin-6-Type Cytokines and Adiponectin on MAPK Activation in the Immortalized Human Chondrocyte C28/I2 Line and Normal Human Chondrocytes
The C28/I2 line of immortalized juvenile human chondrocytes was employed to determine the extent to which recombinant human (rh) interleukin-6 (rhIL-6), the interleukin-6-like cytokine, rh-oncostatin M, and the adipokine, rh-adiponectin, activated extracellularsignal regulated kinase (ERK1/2), p38α mitogen-activated protein kinase (p38α MAPK) and c-Jun-amino-terminal kinase (JNK).
In recent years many progress has been achieved in the biomedical and biopharmaceutical fields particularly in drug delivery and regenerative medicine. This has been possible thanks to the increased expertise in polymers chemistry as well as the advent of innovative techniques of materials manipulation that have lead to the production of new “smart” polymeric devices with peculiar propertiesable to selectively reach almost all areas of the human body, in the case of drug delivery systems, or to reduce the chemical-physical gap between human tissues and synthetic devices, in the case of tissue engineering.