Articles Related to hyperparathyroidism
Surgical Management of Asymptomatic Hyperparathyroidism: Long-Term Follow-Up
Background: Primary hyperparathyroidism (PHPT) is a frequently diagnosed endocrine disease and nowadays it is asymptomatic in the majority of patients. The management of asymptomatic PHPT is still debated in some cases, although
there are evidences that asymptomatic patients may have improved outcomes after curative surgery. In this paper we show
one of the longest follow-ups of surgically treated asymptomatic PHPT, focusing on skeletal long-term effects of surgery.
Methods: We included in the study 21 patients that underwent parathyroidectomy for asymptomatic PHPT at our Institution from 2006 to 2010 with a complete follow-up at 10 years. Data about age, BMI, preoperative serum and urinary
calcium, vitamin D, alkaline phosphatase parathormone, bone densitometry, surgical procedure and histological examination were collected and analyzed.
Results: At follow-up we observed a normalization of PTH, serum calcium and alkaline phosphatase in all patients. Moreover, in all cases the T-score at 1 year increased significantly both at lumbar spine and femoral neck and this is maintained
at long-term follow-up.
Conclusions: Parathyroidectomy can be proposed as a safe therapeutical option in the majority of cases of asymptomatic
PHPT considering the good results of surgery in terms of bone demineralization reduction
Helicobacter pylori Infection and its Potential Association with Idiopathic Hypercalciuric Urolithiasis in Pediatric Patients
A total of 150 patients categorized into 100 cases (urolithiasis-positive) with urinary stone disease, aged from 5 to 18 years, and met the characteristics of idiopathic urolithiasis in children as well as 50 controls (urolithiasis-negative) that had relatively similar demographic criteria except for idiopathic urolithiasis.
Editorial Board Members Related to hyperparathyroidism
Saeid Mordechai Nosrati
Associate Professor of Clinical Medicine
Division of Nephrology
Keck-USC School of Medicine
Los Angeles
USA
Division of Nephrology
Keck-USC School of Medicine
Los Angeles
USA