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Articles Related to mass spectrometry

A Review on Nanoprobes for Sensing, Imaging and Disease Detection

This review focuses on imaging, visualization and detection of diseases using nanoprobes. Several currently available nanoprobes such as fluorescent nanoprobes, upconversion nanoparticle probes, supermagnetic iron oxide nanoprobes, and polymer- and liposome based nanoprobes are discussed.
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A New Bi-Functional Derivative of Polyethylene Glycol as Molecular Carrier for Eugenol and Ibuprofen

Eugenol (EU) and ibuprofene (IBU) were covalently bound to a bi-functionalized PEG, used as molecular carrier of drugs and the release kinetics of the two bioactive molecules was studied in vitro in buffer solution at pH 7.4, in simulated gastric fluid and in mouse plasma.
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Proteomics in Diagnosis: Past, Present and Future

In the post genomic era when several proteomes are on the verge of completion, promising field of protein based diagnostic techniques is emerging. Although protein detection have been used for a long time in clinical diagnostic test, yet high throughput proteomics approaches along with systems biology could be a step forward, towards the development of next generation diagnostic tools and pave a way for personalized medicine.
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In-Vitro Antibacterial / Antifungal Screening of 2-Chloroquinoline Scaffold Derivatives

A series of differentiated 2-chloroquinoline derivatives (3-26) having various spacer groups between 2-chloroquinoline and aryl or heteroaryl ring were synthesized by chemical reactions involving nucleophilic addition, nucleophilic substitution, esterification and cyclization.
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Identification of Pyrrolidinophenone-type Designer Drugs by Gas Chromatography/ Time-of-Flight Mass Spectrometry

Use of gas chromatography (GC) combined with time-of –flight mass spectrometry (TOFMS) with soft ionization generated with three different plasma gases (i.e., Xe, Kr, Ar) was evaluated for the identification of several pyrrolidinophenone-type designer drugs that are commercially available.
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A Comparison of Blood Amino Acid Concentrations Following Ingestion of Rice and Whey Protein Isolate: A Double-Blind Crossover Study

This study investigated comparative concentrations of individual amino acids, total amino acids (TAA), non-essential amino acids (NEA) and essential amino acids (EAA) in the blood after the administration of Rice Protein Isolate (RPI) compared to Whey Protein Isolate (WPI).
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Identification of Designer Drugs using Gas Chromatography High-Resolution Mass Spectrometry and a Soft-Ionization Source

Gas chromatography-mass spectrometry (GC-MS) with electron ionization (EI) or chemical ionization (in positive or negative mode) plays an important role in the forensic analysis of designer drugs.
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Toxicological Screening and Quantitation Using Liquid Chromatography/Time-of-Flight Mass Spectrometry

In recent years, an increasing number of new designer-drugs have increased the demands for general toxicological screening [1]. Limited screening based on immunoassays is commonly used in clinical toxicology, whereas more comprehensive approaches are common in forensic toxicology such as screening based on Gas or Liquid Chromatography (GC or LC) approaches.
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Quantitative Analysis of 30 Drugs in Whole Blood by SPE and UHPLC-TOFMS

An Ultra-High Pressure Liquid Chromatography Time-of-Flight Mass Spectrometry (UHPLC-TOF-MS) method for quantitative analysis of 30 drugs in whole blood was developed and validated. The method was used for screening and quantification of common drugs and drugs of abuse in whole blood received from autopsy cases and living persons.
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Development of a Stability Indicating UPLC-MS/MS Method for Rapid and Reliable Determination of Fenofibrate in Marketed Product (Lypanthyl® 200M) and Human Plasma

A reliable, fast, sensitive and selective Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS) method has been developed and validated for the determination of fenofibrate in marketed product (Lipanthyl) and human plasma. The chromatographic separation was performed on a reversed-phase Acquity®BEH C18 column (1.7 μm particle size, 50 mm x 2.1 mm ID) with an isocratic elution profile and mobile phase consisting of methanol and water (80:20, %, v/v). To achieve optimum chromatographic condition the influence of mobile phase composition and flow rate was investigated. The total chromatographic analysis time was as short as 2 min.
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Editorial Board Members Related to mass spectrometry

Randazzo Antonio

Associate Professor
Department of Pharmacy
University of Naples Federico II
Italy

Bonghee Lee

Professor
Lee Gil Ya Cancer and Diabetes Institute
Gachon University
Korea

Jurgen Konig

Professor
Department of Nutritional Sciences
University of Vienna
Austria

Hui Xiao

Associate Professor
Department of Pathology
Yeshiva University
United States

Jason W. Locasale

Assistant Professor
Division of Nutritional Sciences
Cornell University
United States

Fa-Yun Che

Associate Professor
Department of Pathology
Albert Einstein College of Medicine
United States

Nilesh W Gaikwad

Assistant Professor
Department of Nutrition/Environmental Toxicology
University of California, Davis
United States

Viorica Lopez-Avila

Research Scientist
Agilent Technologies
United States
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