Articles Related to mucosa

This study aims at describing the CT imaging findings and role of multidetector computed tomography (MDCT) in evaluation of squamous cell carcinoma of buccal mucosa and its staging. The imaging findings in squamous cell carcinoma (SCC) of the oral cavity allow the radiologist to accurately determine the extent and staging of disease thereby help clinicians plan appropriate treatment.

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Intramucosal lipomas are rare colonic polyps that pose diagnostic challenges, but they are important as potential clues to serious medical conditions. One third of intramucosal lipomas are reported to arise in Cowden syndrome, an inherited cancer syndrome.

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This case report presents an unusual variant of generalized aggressive periodontitis that was managed by nonsurgical therapy which included the use of a novel tooth gel. Also, a brief review of the literature is offered as context for this unusual clinical case. The patient, a 40-year old Caucasian female, presented with advanced bone loss involving all teeth, intense inflammation of the attached gingiva and little obvious supra- or subgingival biofilm and dental calculus. Presence of systemic disease, high levels of periodontal microbial pathogens and IL-1α and IL-1β polymorphisms were evaluated and all determined to be negative. Gingival biopsy resulted in a diagnosis of nonspecific inflammation. Treatment consisted of 2- and 3-month intervals for periodontal maintenance appointments and eventually the introduction of an activated edathamil-based tooth gel. Over the subsequent 4-years the patient’s periodontal status stabilized as manifested by no further loss of tooth supporting bone, a reduction in the percentage of periodontal pockets of 4-6 mm depth and a reduction in the percentage of sites exhibiting bleeding upon periodontal probing. The significance of this case report is to emphasize that, even in cases of severe generalized aggressive periodontitis, nonsurgical periodontal therapy can be effective. In addition, it appears that a novel tooth gel containing activated edathamil is effective at reducing gingival inflammation with a concomitant reduction in percent of sites that bleed on periodontal probing.

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Buccal mucosal urethroplasty has revolutionized the surgical management of urethral strictures but the success of the procedure has been variable in different series. We have attempted to understand the interplay between buccal mucosal epithelial cells (BME) and the fibroblasts at the molecular level using connective tissue growth factor (CTGF) as a marker so that translation of this information would help in better urethroplasty outcomes. Materials and Methods: The morphological and functional characteristics of normal urethral fibroblasts (NUF) and urethral stricture fibroblasts (UStF) with and without co-culture with BMEs are compared. The intracellular and extracellular level of CTGF expression in the UStF co-cultured with BMEs was analyzed by using molecular biology methods.

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The nutrition source of developing embryo at early stages is the omphalomesenteric duct which obliterates latter. Failure of this obliteration process brings on omphalomesenteric remnants.

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Hypoglossal schwannomas are rare cranial base neoplasm arising from schwann cells of the XIIth cranial nerve. We report a case of 45 year old lady with history of headache for 2 years and difficulty in swallowing for 1 year. On evaluation, she was found to have left hypoglossal paresis, atrophy of tongue muscles on left side and a smooth oropharyngeal bulge on left side.

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An epidemiologic data pool was formed from cases of SCT submitted as surgical specimens to a Reference Pathology Laboratory serving the Igbo Ethnic Group in South-Eastern Nigeria.

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Eugenol (EU) and ibuprofene (IBU) were covalently bound to a bi-functionalized PEG, used as molecular carrier of drugs and the release kinetics of the two bioactive molecules was studied in vitro in buffer solution at pH 7.4, in simulated gastric fluid and in mouse plasma.

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Gastric type adenocarcinoma with fundic gland differentiation (GA-FG) has been reported as a new, rare, chief cell differentiation composed carcinoma. Clinicopathologically, it exists on the gastric cardia/fundus, with low proliferative activity and low-grade malignancy. Until now, there has been no report of this GA-FG type cancer in the duodenum.

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In this study, we focused on the effect of β-glucan supplementation of children with chronic respiratory problems. We measured the levels of cortisol, salivary IgE and cotinine in 56 children and evaluated the effect of 30 day supplementation with 100 mg/day oral dose of yeast-derived β-glucan. Our results showed strong decrease of cotinine and cortisol levels in saliva of β-glucan-supplemented children.

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