Articles Related to randomized
A Randomized Double-Blind Placebo Controlled Clinical Trial Evaluating the Effects of an Investigational Study Product on Exercise Induced Muscle Soreness, Markers of Inflammation, Muscle Damage and Exercise Performance in Healthy Males
Gherkin, a pure botanical extract from cucumber is a phytonutrient rich vegetable which may have been shown to have anti-inflammatory and pain relieving properties. The purpose of this randomized double-blind placebo study was to determine the effects of Gherkin (Cuvitus™, Actido®)on exercise performance, markers of inflammation and acute muscle soreness in healthy males.
To evaluate the value and safety of labetalol in comparison to Alfa methyldopa in treatment of pregnant women with pregnancy-induced hypertension (PIH). 264 patients with PIH were randomly distributed to take either methyldopa (group 1) labetalol (group 2). or Intake of medications with respect to Age, gravidity, Blood Pressure measurement, albumin in urine measurement Levels, Side Effects, dose of the drug, increasing duration of pregnancy, mode of delivery, Perinatal safety and APGAR scores were studied. The statistical level of significance was taken at P<0.05.
Efficacy of Vitamin C Vaginal Suppository in Treatment of Bacterial Vaginosis a Randomized Controlled Trial
The aim of the current study was to compare the efficacy and side effects of vaginal vitamin C suppository and vaginal metronidazole in treatment of bacterial vaginosis. Double-blind randomized controlled trial. The study included women who presented to the outpatient gynecological clinic with a diagnosis of bacterial vaginosis by amsels criteria. The included eligible women were randomly allocated in one of two groups: group I, including women who received vitamin C vaginal suppository once daily at bed time for 6 days; and group II, including women who received metronidazole 500 mg vaginal suppository once daily at bed time for 6 days. All included women were reviewed in 8-14 days after completion of treatment for reevaluation.
Bioequivalence Study of Two Oral-Capsule Formulations of Omeprazole 20 mg in Combination with Sodium Bicarbonate in Healthy Mexican Adult Volunteers
In Mexico, the immediate-release formulation of omeprazole 20 mg in combination with 1100 mg of sodium bicarbonate (oral capsules) is indicated for patients over 18 years for the treatment of gastritis, reflux, heartburn and the sensation of emptiness caused by the excessive acid production.
Dentin hypersensitivity (DH) is generally described as “a brief, sharp, and acute pain emanating from exposed dentin in response to thermal, tactile, osmotic, or chemical stimuli, as well as exposure to air that cannot be attributed to any dental anomaly or pathology”.
Peritoneal Dialysis (PD) is one of the 3 well-established modalities of renal replacement therapy used in patients with renal failure. Despite its significant role as a successful method of renal replacement therapy, PD is highly associated with peritonitis and catheter-related infections.
Randomized Study of the Effects of Statin on Inflammatory and Prothrombotic States in Obese Adolescents
Obesity is a major public health concern in many countries. In Europe 4.1% of the girls and 5.4% of the boys aged 10-12 years are obese according to the International Obesity Task Force criteria.
C-MAC Video Laryngoscopy Versus Flexible Fiberoptic Laryngoscopy in Patients with Anticipated Difficult Airway: A Randomized Controlled Trial
Tracheal intubation is one of the most common medical procedures performed in hospitals. On one hand, it is highly successful and easy to perform using a rigid laryngoscope. On the other hand, hypoxic brain damage and death may result rapidly if it is unsuccessful.
A Laparoscopic Assisted Minilaparotomy Hysterectomy approach for Very Large Fibroid Uteri of more than 1000 grams – A Preliminary Study
Minilaparotomy has been used for tubal sterilization for decades. It became a new surgical idea described by some who performed minilaparotomy hysterectomy and achieved outcomes that were less invasive than those of traditional open laparotomy. Pelosi and Pelosi 2004 reported a minilaparotomy procedure in patients in whom vaginal hysterectomy was considered contraindicated. Their procedure offered a safe alternative with minimal access and good outcome.
Nutrition Research and Human Disease: A Critical Appraisal of Mechanistic Research, Cohort Studies, and Randomized Trials
A major part of nutrition research consists of the investigation of how food components affect the biochemical and physiologicalprocesses within the body. The rationale is that this mechanistic research will lead to a fuller understanding of disease etiology thereby generating information of practical value for the treatment and prevention of disease.
Changes in Heart Function in Patients with Heart Failure after the Completion of Land-Based and Partial Water-Based Exercise Programmes
Opinion is divided as to the changes in ventricular function brought about by exercise, with few studies on water-based exercise programmes for heart-failure patients. This study investigates whether following a partial water-based exercise programme could lead to an earlier improvement in ventricular function in heart-failure patients compared with a land-based exercise programme.
Anti-Inflammatory and Anti-Arthritic Efficacy and Safety of Purified Shilajit in Moderately Arthritic Dogs
The objective of this investigation was to evaluate the efficacy and safety of purified Shilajit in moderately arthritic dogs. Ten client-owned dogs in a randomized double-blinded study received either a placebo or Shilajit (500 mg) twice daily for a period of five months. Dogs were evaluated each month for physical condition (body weight, body temperature, heart rate, and respiration rate) and pain associated with arthritis (overall pain, pain from limb manipulation, and pain after physical exertion).
Understanding the Value of Case Reports and Studies in the Context of Clinical Research, Research Design, and Evidence-Based Practice
Case reports and studies may be defined as the non-experimental description of an individual or a few of cases in terms of new or unusual presentation of the diseases, an unexpected disease course or pathophysiology, and new effects (either beneficial or detrimental) of existing medications or procedures. Although they suffer from the non-experimental nature and other potential bias and errors, case reports and studies have played and will continue to play an important part in the advancement of medicine.
Case reports are considered to be brief reports describing an episode of clinical case or a small number of cases. They may describe new or uncommon diagnoses, unusual outcomes or prognosis, new or unusual imaging findings, new or infrequently used therapies and side effects of therapy not previously discovered in clinical trials