Articles Related to ATP
Beneficial Effects of Vitamin E against Indomethacin-induced Glutathione Depletion, Acetylcholinesterase Activity, (Na+,K+)-ATPase Activity and Osmotic Fragility of Erythrocyte
Indomethacin, is a well-known non-steroidal anti-inflammatory drug (NSAID), a cyclooxygenase inhibitor and extensively used as a medicine to reduce pain, fever, stiffness, swelling or inflammatory responses. Indomethacin inhibits both COX-1 and COX-2, which in turn, inhibits the production of prostaglandins in the gastrointestinal tract and disrupts the mucosal lining in the gastrointestinal tract leading to intestinal bleeding and perforation.
Novel Multi-Functional Dental Cement for Enamel Remineralization and AntiCariogenic Bacteria Activity
This experimental study evaluated the release of fluoride and several minerals related to remineralization from novel functional cement, apatite ionomer cement (AIC), and its anti-bacterial properties compared with glass ionomer cement (GIC) and surface pre-reacted glass-ionomer filler containing composite resin (giomer). Conventional GIC (Fuji III, GC Co., Tokyo, Japan) was used as the control and fundamental materials. In the AIC powder, 28% wt of GIC powder was replaced with spherical-shaped hydroxyapatite powder. The giomer, BeautiSealant (Shofu Co., Kyoto, Japan), was used as a positive control. Each specimen was immersed in deionized water and analyzed by inductively coupled plasma atomic emission spectrometry (for Al, Si, P, Ca and Sr) and a fluoride-selective electrode. Antibacterial activity against Streptococccus mutans was evaluated using the adenosine-5’-triphosphate luminescence method. Concentrations of released ions from AIC specimens were significantly higher than those from GIC and giomer specimens. Regarding antibacterial activity, luminescence intensity of the AIC group was significantly lower than that of the control and giomer groups. It was concluded that AIC could be a most suitable material for pit and fissure sealant for enamel remineralization and anti-cariogenic and -bacterial activity.
Protective Ability of Vitamin E Against Acetylsalicylic Acid-Induced Glutathione Depletion, Acetylcholinesterase and (Na+ ,K+ )-ATPase Activities, and Erythrocyte Osmotic Fragility
Acetylsalicylic acid (ASA), a well-recognized non-steroidal anti-inflammatory drug (NSAID), is well known for the treatment of fever, pain alleviation and inflammatory conditions, especially for the prevention of cardiovascular complications and disorders. However, ASA has been reported to cause hepato- and gastro-toxicities.
ATP-binding cassette (ABC) transporters are the largest and most ancient family of transmembrane proteins with representatives in all phyla from prokaryotes to humans. Systematic searches were performed using PSI-Blast program on NCBI to identify sorghum ABC transporters. The identified proteins were subjected to phylogenetic and domain topology analyses and were classified and named according to the Human Genome Organisation (HUGO) system of classification and unified plant nomenclatural system. As part of the survey, the subcellular location, the presence of signal peptide and physicochemical parameters were determined.
This paper does not present new experimental data. It is based on existing literature and 40 years of clinical experience as an anesthesiologist. Author believes that it is necessary to look into clinical guidelines for some common, but serious medical conditions
Expression Profile of Hepatic Metallothionein-I and ATP7B, and Brain Metallothionein-III and Acetyl cholinesterase Genes in Wistar Rat Model for Non-Wilsonian Brain Copper Toxicosis
Cognitive waning due to chronic copper (Cu) intoxication in animal models is increasingly being reported; notwithstanding, information regarding molecular basis of Cu accumulation and neurobehavioral impairments remains fragmentary.
Development of Severe Hypophosphatemia from Acquired Fanconi Syndrome during Treatment with Abiraterone
The first patient was a 77 year old man who had been on abiraterone for 12 months before his phosphorous was checked. At that point, it was 0.6 mg/dl, which is severely decreased. A full work up for hypophosphatemia showed normal parathyroid hormone and 25-hydroxyvitamin D. A urine study showed inappropriate excretion of phosphorous along with aminoaciduria and normoglycemic glucosuria.
The DNA mismatch repair (MMR) system is necessary for the maintenance of genomic stability. The MMR system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops (IDLs) and heterologies generated during DNA replication and recombination.
Gastric Type Adenocarcinoma with Fundic Gland Differentiation in the Duodenum Resected by ESD (Endoscopic Submucosal Dissection)
Gastric type adenocarcinoma with fundic gland differentiation (GA-FG) has been reported as a new, rare, chief cell differentiation composed carcinoma. Clinicopathologically, it exists on the gastric cardia/fundus, with low proliferative activity and low-grade malignancy. Until now, there has been no report of this GA-FG type cancer in the duodenum.
Mitogen-Activated Protein Kinase (MAPK) pathway is a signal transduction pathway that functions in a wide range of physiological and pathophysiological cellular events including cell proliferation, differentiation, apoptosis, migration, inflammation, metabolic disorders and diseases.