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Articles Related to chronic

Maintenance Hemodialysis Exacerbate Aluminum and Arsenic Toxicity in Chronic Kidney Disease Patient

Maintenance hemodialysis (MHD) is the most effective interventional therapy for patients with chronic kidney disease (CKD). Our aim was to investigate the serum levels of aluminum (Al) and arsenic (As) in CKD patients. Methods: A total of 29 CKD patients receiving MHD were surveyed for selected biochemical, and dialysis quality indices. Serum Al and As levels were measured before and after MHD. Statistical analyses included independent samples t-test or Mann-Whitney, Kaplan-Meier, Pearson, or Spearman's rho correlations
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Approach to and Management of a Adynamic Bone Disease in Hemodialysis Patients-A Review

Chronic kidney disease (CKD) is now a global public health epidemic with increasing rates reported all over the world. Currently, more than 850 million people are estimated to live with CKD worldwide. Bone and mineral disorders (CKD-MBD) form an integral part of the management of CKD patients. CKD-MBD encompasses distinct abnormal pathology within the spectrum of Renal Osteodystrophy (ROD), including osteitis fibrosa cystica, osteomalacia, adynamic bone disease (ABD), mixed lesions, and osteoporosis. ABD is primarily characterized by decreased or absent bone formations along with low cellularity of both osteoblasts and osteoclasts as well as thin osteoid seams and minimal or absent peri trabecular/marrow fibrosis. ADB is also associated with a greater risk of vascular calcification and fractures negatively affecting patient outcomes. It is unclear if all forms of ABD are truly pathological or milder forms of ADB could be a compensatory mechanism to guard against bone loss. In this article, we describe a hemodialysis patient profile of ADB with a review of this entity
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A Single-Center Experience in Alport Syndrome

Alport Syndrome is a hereditary condition that affects the collagen in the basement membrane and is characterized by microscopic hematuria, sensorineural hearing loss, increasing renal dysfunction, and ocular abnormalities. It is more common between the ages of 20 and 30. Men and women are equally affected. However, the prognosis of men is worse than women due to renal failure. The purpose of this study is to evaluate the demographic and clinical findings of patients with Alport Syndrome in our center
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Does Body Mass Index Influence the Onset and Prognosis of Colorectal Cancer?

Overweight and obesity are considered an increasing colorectal cancer risk factor. The association between excess body weight and colorectal cancer appears to be related to a state of systemic low-grade inflammation, due to an overproduction of proinflammatory cytokines.
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Clinical Impact of Laparoscopic Cholecystectomy to Chronic Calculous Cholecy-stitis: A Retrospective Study

The Aims: The retro-prospective clinical study was to compare these two methods of laparoscopic and classical cholecystectomy. To prove the postoperative benefits of laparoscopic treatment are, less pain, aesthetic aspect without surgical scarring and shorter hospital stay, faster return to social activities as well as more cost effective. Material and Methods: The operated patients, from January 2017 to December 2019 in the abdominal surgery ward in Gjilan. Important data for the study are taken from the operative list, history of the disease, adequate list compiled specifically for this study. The study included 389 patients with chronic calculous cholecystitis. Results: According to the results obtained for calculous diseases of the biliary system are predisposed persons with blood group O, Rh-positive, with 44.2%, followed by group A + with 29.5%, group B + with 14.7%. Other blood groups and Rh factors are below 6.5%. Statistical point of view is significant (p <0.05). The study analyzed, C-reactive protein (CRP) values in both research group (RG) and control groups (CG); CRP by gender; and by age group. RG recorded 76.9% of females with increased CRP values> 6, while 23.1% of males. The percentage difference in statistical terms is significant p <0.05. Conclusion: The results obtained have shown that there are no significant differences in the presentation of intra-operative complications in terms of gender and age, to both methods. Optimization measures for postoperative management of patients after laparoscopic cholecystectomy. Continuing education in laparoscopic surgery is important for successful management.
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A Chronic Myeloid Leukemia Case Showing Spontaneous Ph-positive Clone Regression and Bone Marrow Hypoplasia after a Short Treatment with Dasatinib

Dasatinib is an orally bioavailable second generation TKI, more potent than imatinib. Bone marrow aplasia or hypoplasia secondary to TKI therapy is an uncommon adverse event. We report here the first case of chronic myeloid leukemia in chronic phase shortly treated with dasatinib that developed a prolonged bone marrow hypoplasia with concomitant response on the hematological disease with gradual improvement of the cytogenetic and molecular response after dasatinib discontinuation, without use of any other TKI therapy.
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The Simultaneous Activation of Nrf2 and Antioxidant Compounds may reduce the Risk, Progression, and Improve the Management of Diabetes by Reducing Oxidative and Inflammatory Damages

Despite extensive research, the incidence of diabetes continues to increase, and the management of diabetes needs improvement, because in 2016, more than 100,000 patients had lower extremity amputated, suffered ischemic heart disease and stroke. Analysis of investigations indicates that increased oxidative stress and chronic inflammation enhance the risk, progression, diabetic–related complications, and reduce effectiveness of drug therapy. Therefore, simultaneously attenuation of these cellular abnormalities may help in reducing the risk of development, progression, and prolonging the effectiveness of drug therapy.
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Chronic Exposure to Artificial Light Spectra at night alter Neurobehaviour and Neurotransmitter levels in Albino Rats

Artificial light at night has been reported to have significant effects on the physiology and behaviour of animals by its impact on their circadian rhythm. This study investigated the effect of artificial light spectra at night on neurotransmitter activities and neurobehavioural changes in the albino rat. Blue (470 nm) and red (665 nm) lights were used; with ambient light and darkness serving as positive and negative controls, respectively. The rats were exposed to daylight from 6 am to 6 pm and 12 hours of artificial light (6 pm - 6 am) daily (light sources were 13 Watt compact florescent electric bulbs). Neurobehavioural outcomes were measured using the Open Field Test (OFT) and Morris Water Maze (MWM).
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Association between Chronic Obstructive Pulmonary Disease Severity and Platelet Values

To investigate the association between platelet values and COPD severity using linear variables in order to better explain and explore these correlations.
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Unexpected Improvement of Chronic Neurological Disease after Recovery from COVID-19 Infection in Four Patients

During the COVID-19 pandemic, physicians actively searched for adverse neurological complications or coagulopathyrelated strokes, but no protective effects were yet reported. We hereby describe our observations at a Geriatrics / Neurology facility on a range of neurological disorders encountered among COVID-19 patients followed for disabling neurological disease (degenerative or post traumatic dementia). We observed a very significant clinical improvement in 4 patients aged 43 to 78, who were in nursing skills home or at home and followed up for a disabling neurological disease for 2 to 5 years. They were affected by COVID-19 between March and October 2020.
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The Comparison between the Effect of Action Observation and that of Bimanual Movement in Chronic Hemiplegia

Various interventions have been investigated for the purpose of regaining the limited ADL of chronic stroke hemiplegia. However the application of intervention depending on motor function is still unclear.
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Factors Affecting Exercise Self-efficacy in Predialysis Chronic Kidney Disease Patients

There was significant evidence to suggest that exercise improves physical function, symptom burden, and quality of life in predialysis chronic kidney disease (CKD) patients. However, most CKD patients cannot adherence to minimum recommended levels of exercise.
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Nutrition Intervention of Patient with Chronic Kidney Disease (Stage 4) on Maintenance Hemodialysis

We report the case of 27 years old, female patient suffering from CKD (Stage 4) on Maintenance Hemodialysis. Dietary intervention was tailored for her using her past medical history and dietary intake. The dietary interventions were planned in 4 steps for 12 weeks that included nutritionally adequate food intake, Increase frequency of meals, modification & improvement in food preparation techniques, provision of educational material related to diet in dialysis.
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Development of Chronic Obstructive Pulmonary Disease (COPD) in Patients Infected with Human Immunodeficiency Virus (HIV)

Chronic Obstructive Pulmonary Disease (COPD) is considered a public health problem and its prevalence increases over the years, in Brazil. Currently, 37 million people are living with HIV and 4 million of these patients infected with the virus may have COPD. However, many of these cases may be underreported. In Brazil, these two clinical situations (HIV infection and COPD) have a high incidence, which causes a great expense for the public health, increased morbidity and mortality of these patients. We observed that, in the national literature, there is a gap on the association between these two scenarios.
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Obesity as Behavioral Risk Factors of Chronic Noncommunicable Diseases in Young Gabonese Population

Obesity increases of prevalence of noncommunicable diseases (NCDs) in young active populations worldwide. We sought to investigate the status of young men (n=200) and women (n=200) aged from 18 to 39 years old, living at Libreville, by examining their lifestyles and eating habits, and measuring their anthropometric parameters, including, height, weight, body mass index (BMI), percentages of total muscles, lean mass, body and visceral fats, as well as metabolic age and metabolism at rest.
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Editorial Board Members Related to chronic

OMAR A. OBEID

Professor of Human Nutrition
Department of Nutrition and Food Science
American University of Beirut
Lebanon

Abdoulaye Diallo

Department of Physical Medicine and Rehabilitation
University of Texas Rio Grande Valley
USA

Jane F Manakil

Professor
Department of Dentistry and Oral Health
Griffith University
Australia

DAVID R. BLACK

Professor Emeritus
Department of Health and Kinesiology
Purdue University
United States

Eric Fung

Professor of Pharmacology
Department of Oral Biology
University of Nebraska Medical Center College of Dentistry
United States

Robert R. Redfield

Professor
Department of Immunology and Microbiology
University of Maryland
United States

Dilip K. Tosh

Laboratory of Bioorganic Chemistry
National Institute of Diabetes and Digestive and Kidney Diseases
National Institutes of Health
USA

Hamdy Ahmad Sliem

professor of internal medicine and endocrinology
Suez Canal University
Egypt

SARA J. SHUMWAY

Professor
Department Cardiothoracic Surgery
University of Minnesota
United States

Sanja Ilic

Assistant Professor
Department of Human Nutrition
The Ohio State University
United States
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