Articles Related to chronic

Alport Syndrome is a hereditary condition that affects the collagen in the basement membrane and is characterized by microscopic hematuria, sensorineural hearing loss, increasing renal dysfunction, and ocular abnormalities. It is more common between the ages of 20 and 30. Men and women are equally affected. However, the prognosis of men is worse than women due to renal failure. The purpose of this study is to evaluate the demographic and clinical findings of patients with Alport Syndrome in our center

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Overweight and obesity are considered an increasing colorectal cancer risk factor. The association between excess body weight and colorectal cancer appears to be related to a state of systemic low-grade inflammation, due to an overproduction of proinflammatory cytokines.

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The Aims: The retro-prospective clinical study was to compare these two methods of laparoscopic and classical cholecystectomy. To prove the postoperative benefits of laparoscopic treatment are, less pain, aesthetic aspect without surgical scarring and shorter hospital stay, faster return to social activities as well as more cost effective. Material and Methods: The operated patients, from January 2017 to December 2019 in the abdominal surgery ward in Gjilan. Important data for the study are taken from the operative list, history of the disease, adequate list compiled specifically for this study. The study included 389 patients with chronic calculous cholecystitis. Results: According to the results obtained for calculous diseases of the biliary system are predisposed persons with blood group O, Rh-positive, with 44.2%, followed by group A + with 29.5%, group B + with 14.7%. Other blood groups and Rh factors are below 6.5%. Statistical point of view is significant (p <0.05). The study analyzed, C-reactive protein (CRP) values in both research group (RG) and control groups (CG); CRP by gender; and by age group. RG recorded 76.9% of females with increased CRP values> 6, while 23.1% of males. The percentage difference in statistical terms is significant p <0.05. Conclusion: The results obtained have shown that there are no significant differences in the presentation of intra-operative complications in terms of gender and age, to both methods. Optimization measures for postoperative management of patients after laparoscopic cholecystectomy. Continuing education in laparoscopic surgery is important for successful management.

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Dasatinib is an orally bioavailable second generation TKI, more potent than imatinib. Bone marrow aplasia or hypoplasia secondary to TKI therapy is an uncommon adverse event. We report here the first case of chronic myeloid leukemia in chronic phase shortly treated with dasatinib that developed a prolonged bone marrow hypoplasia with concomitant response on the hematological disease with gradual improvement of the cytogenetic and molecular response after dasatinib discontinuation, without use of any other TKI therapy.

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Despite extensive research, the incidence of diabetes continues to increase, and the management of diabetes needs improvement, because in 2016, more than 100,000 patients had lower extremity amputated, suffered ischemic heart disease and stroke. Analysis of investigations indicates that increased oxidative stress and chronic inflammation enhance the risk, progression, diabetic–related complications, and reduce effectiveness of drug therapy. Therefore, simultaneously attenuation of these cellular abnormalities may help in reducing the risk of development, progression, and prolonging the effectiveness of drug therapy.

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Artificial light at night has been reported to have significant effects on the physiology and behaviour of animals by its impact on their circadian rhythm. This study investigated the effect of artificial light spectra at night on neurotransmitter activities and neurobehavioural changes in the albino rat. Blue (470 nm) and red (665 nm) lights were used; with ambient light and darkness serving as positive and negative controls, respectively. The rats were exposed to daylight from 6 am to 6 pm and 12 hours of artificial light (6 pm - 6 am) daily (light sources were 13 Watt compact florescent electric bulbs). Neurobehavioural outcomes were measured using the Open Field Test (OFT) and Morris Water Maze (MWM).

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To investigate the association between platelet values and COPD severity using linear variables in order to better explain and explore these correlations.

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During the COVID-19 pandemic, physicians actively searched for adverse neurological complications or coagulopathyrelated strokes, but no protective effects were yet reported. We hereby describe our observations at a Geriatrics / Neurology facility on a range of neurological disorders encountered among COVID-19 patients followed for disabling neurological disease (degenerative or post traumatic dementia). We observed a very significant clinical improvement in 4 patients aged 43 to 78, who were in nursing skills home or at home and followed up for a disabling neurological disease for 2 to 5 years. They were affected by COVID-19 between March and October 2020.

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Various interventions have been investigated for the purpose of regaining the limited ADL of chronic stroke hemiplegia. However the application of intervention depending on motor function is still unclear.

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There was significant evidence to suggest that exercise improves physical function, symptom burden, and quality of life in predialysis chronic kidney disease (CKD) patients. However, most CKD patients cannot adherence to minimum recommended levels of exercise.

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We report the case of 27 years old, female patient suffering from CKD (Stage 4) on Maintenance Hemodialysis. Dietary intervention was tailored for her using her past medical history and dietary intake. The dietary interventions were planned in 4 steps for 12 weeks that included nutritionally adequate food intake, Increase frequency of meals, modification & improvement in food preparation techniques, provision of educational material related to diet in dialysis.

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Chronic Obstructive Pulmonary Disease (COPD) is considered a public health problem and its prevalence increases over the years, in Brazil. Currently, 37 million people are living with HIV and 4 million of these patients infected with the virus may have COPD. However, many of these cases may be underreported. In Brazil, these two clinical situations (HIV infection and COPD) have a high incidence, which causes a great expense for the public health, increased morbidity and mortality of these patients. We observed that, in the national literature, there is a gap on the association between these two scenarios.

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Obesity increases of prevalence of noncommunicable diseases (NCDs) in young active populations worldwide. We sought to investigate the status of young men (n=200) and women (n=200) aged from 18 to 39 years old, living at Libreville, by examining their lifestyles and eating habits, and measuring their anthropometric parameters, including, height, weight, body mass index (BMI), percentages of total muscles, lean mass, body and visceral fats, as well as metabolic age and metabolism at rest.

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The purpose of the study was to evaluate the management of patients treated with Imatinib for Chronic Myeloid Leukemia (CML) in the Department of Clinical Hematology of the Yalgado OUEDRAOGO University Hospital in Ouagadougou, Burkina Faso.

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Insomnia is a common sleep disorder with a prevalence of 10-15% in the population.

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