ATP-binding cassette (ABC) transporters are the largest and most ancient family of transmembrane proteins with representatives in all phyla from prokaryotes to humans. Systematic searches were performed using PSI-Blast program on NCBI to identify sorghum ABC transporters. The identified proteins were subjected to phylogenetic and domain topology analyses and were classified and named according to the Human Genome Organisation (HUGO) system of classification and unified plant nomenclatural system. As part of the survey, the subcellular location, the presence of signal peptide and physicochemical parameters were determined.
NIH Funded Articles
- Molecular Mechanism Linking BRCA1 Dysfunction to High Grade Serous Epithelial Ovarian Cancers with Peritoneal Permeability and Ascites
- Predictors of Obstructive Sleep Apnea Risk among Blacks with Metabolic Syndrome
- Acculturation and Subclinical Atherosclerosis among U.S. South Asians: Findings from the MASALA study
- Wake-up Strokes Are Similar to Known-Onset Morning Strokes in Severity and Outcome
- Objectively Coding Intervention Fidelity During A Phone-Based Obesity Prevention Study
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Endocardial Approach for Substrate Ablation in Brugada Syndrome: Epicardial, Endocardial or Transmural Substrate?
Background: Radiofrequency ablation (RFA) in Brugada syndrome (BrS) has been performed both endocardially and epicardially. The substrate in BrS is thus unclear. Objectives: To investigate the functional endocardial substrate and its correlation with clinical, electrophysiological and ECG findings in order to guide an endocardial ablation. Methods: Thirteen patients (38.7±12.3 years old) with spontaneous type 1 ECG BrS pattern, inducible VF with programmed ventricular stimulation (PVS) and syncope without prodromes were enrolled. Before to endocardial mapping the patients underwent flecainide testing with the purpose of measuring the greatest ST-segment elevation for to be correlated with the size and location of substrate in the electro-anatomic map
Traumatic pseudoaneurysm of the superficial temporal artery is a very rare lesion and usually presents as a painless pulsatile mass in the temporal region a few weeks after trauma.
Helicobacter pylori Infection and its Potential Association with Idiopathic Hypercalciuric Urolithiasis in Pediatric Patients
A total of 150 patients categorized into 100 cases (urolithiasis-positive) with urinary stone disease, aged from 5 to 18 years, and met the characteristics of idiopathic urolithiasis in children as well as 50 controls (urolithiasis-negative) that had relatively similar demographic criteria except for idiopathic urolithiasis.