Articles Related to HL

spinal muscular atrophy is an autosomal recessive disorder characterized by degeneration of alpha motor in anterior horn cells of brain and spinal cord, which results in muscular atrophy, hypotonia, fasciculations, areflexia, paralysis and even death in most severe cases. The underlying cause of this disease is biallelic loss of survival motor neuron 1 (SMN1) gene. Depending upon the clinical features & patient's age, SMA is classified into different distinctive sub types

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High tunnels can provide several benefits to horticultural crops, including environmental stress protection such as hail, frost, excessive rainfall, and high wind. In hot and sunny areas, high tunnel is one of the cooling ways for modifying the microclimate and maximizing crop development. Present study was carried out to assess the effect of different type of high tunnels on banana growth, yield, and fruit quality characteristics. Net houses, poly net houses, UV poly shed houses, and open field (control) conditions are among the experimental treatments. The results revealed that the plants produced in the poly net house condition had maximum pseudo stem height (171.00cm), stem girth (68.66 cm), chlorophyll content (57.63), number of fruits (140), number of hands (9.66), individual fruit weight (125.00) and pulp: peel ratio (3.35) of bananas as compared to the other treatments. Quality parameters like total soluble solid (21.78°Brix), ascorbic acid (10.24 mg/100g), total sugar (25.44%), and reducing sugar (15.75%) were higher in fruits grown in poly net house. The study revealed that the poly net house is the best growing environment for bananas in terms of growth, yield, and quality attributes.

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There are several energy drinks available in the market such as Red Bull, Sting, Rebound, Power Up! Triple X Energy Drink, and so on. After the Red Bull drink was introduced in the market in1990s, Energy drinks started to gain popularity and afterwards it became a common name especially among teenagers and young adults [1]. Most energy drinks are caffeinated nonindulgent beverages that are professed to give an additional increase in energy for day-by-day work, increase alertness, and improve athletic performance and mood. There are even certain shreds of evidence present to substantiate these claims, but the effects of these drinks on mental and physical health cannot be neglected. There are reports of adverse events such as insomnia, anxiety, cardiovascular events, seizures, tachycardia, type-2 diabetes, and even death are associated with the consumption of these drinks [2]. This review will focus on energy drinks, their ingredients, health risks associated with these drinks, and will also suggest some recommendations such as changes in marketing, providing education to children regarding adverse effects of these drinks, and further research should be carried out in this domain.

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The aim of this research was to assess the biochar ability to protect the photosynthesis process face to Cd contamination, especially, when nitrogen fertilizer was added at adequate amount. Culture of tomato seedlings was conducted on pots containing soil added with different portion of biochar (0, 3.5 and 7%) and nitrogen (3 or 6g NH4NO3). Irrigation was done by water (control condition) or Cd solution (150µM). Data showed that regardless presence of Cd, synchronously addition of high nitrogen fertilizer (6g) and biochar (7%) in the culture medium resulted in fresh matter production, photosynthetic pigment (Chlorophyll a) and mineral elements content enhancement. Similar observation was shown concerning the mineral nutrition (nitrogen, phosphorus and potassium contents).

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In order to evaluate the possibilities of valorisation as feed of the plant biomass produced during wastewater treatment in constructed wetlands, a study of the in vitro digestibility and gas production of Echinochloa crus-pavonis was carried out in the Laboratory of Animal Production and Nutrition of the University of Dschang. The in vitro digestibility of Echinochloa crus-pavonis was evaluated at different harvesting periods

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3D gas-solid coupled symmetrical numerical model was developed on the basis of multiphysics finite element platform to study coal seam fracture stimulation under the high pressure gas impact loading generated by the highly pressurized multi-discharge carbon dioxide gas fracturing technique to improve pre gas drainage efficiency. The purposes of this study are to understand the natural and operational factors contribute to coal seam fracture stimulation and improvement of coal seam gas drainage efficiency and the interaction of these parameters.

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Fluoxetine Hydrochloride (FH), a selective serotonin reuptake inhibitor (SSRI) is a drug of choice in depression, obsessive-compulsive disorder (OCD), bulimia nervosa, etc. Though tablet, capsules, oral solution, or syrup are currently available conventional dosage form of FH, modified or immediate-release formulations for fast onset of action is of utmost importance.

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Different types of Glutaredoxins (GRXs) that play a major role in cellular anti-oxidative reactions have been studied for their structure and function from various organisms. Glutathione (GSH), an anti-oxidant with several medical benefits, binds to GRXs. This work has structurally characterized GRX2 from C. reinhardtii (CrGRX2) using biophysical, molecular modelling, and isothermal titration calorimetry (ITC) techniques. CrGRX2 adopts the classical GRX-Trx fold consisting of five β-strands surrounded by four α-helices that bind to GSH with moderate strength through a cysteine residue. The residues involved in the interaction closely match with those observed for E. coli and human counterparts, indicating that the cellular GSH-GRXs antioxidant system is highly conserved.

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The clinical course of our patient highlights an atypical presentation of thromboembolic disease related to pregnancy, a thrombophlebitis of the right ovarian vein with endocaval floating thrombus. The diagnosis remains difficult since it is a rare entity with an atypical presentation but with serious medical consequences.

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The aim of the present work was formulation and evaluation of in-situ gelling system of Ciprofloxacin Hydrochloride. The poor bioavailability and therapeutic response exhibited by conventional ophthalmic solution due to rapid precorneal elimination of the drug may be overcomed by the use of in-situ gel forming system that are installed as drop into the eye and undergo sol to gel transition in the cul-de-sac.

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The main objective of the present work was to study the population trend of the Seychelles scale, Icerya seychellarum (Westwood) (Hemiptera: Monophlebidae) on guava trees at Abu-Suwair district in Ismailia Governorate, Egypt during two consecutive years (2018-19). The results showed that insect population was recorded on guava trees all the year round and has three peaks of seasonal activity per year i.e., June, August/September and November.

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The use of Neurodynamic mobilizations to improve those qualities had not been enough studies; the aim of this research is to investigate the knowledge, use, and awareness of Palestinian physiotherapists about the Neurodyanimc mobilization (NDM) effect on the above-mentioned variables.

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The concept of an effective cognitive boosting nootropic supplement is gaining traction with consumers, neuroscientists and regulators alike and it is therefore unsurprising that scientifically validated Nootropics are highly prized. New research demonstrates edible crops could be useful sources to mine for new nootropics; plant extracts enriched with an array of cognitive enhancing metabolites. There is merit in investigating these plant species. Metadata has identifies consuming specific fruit and vegetables positively affects cognitive function; therefore these same edible crop plants present as opportunities for developing nootropic formulations. This hypothesis is supported by positive data obtained through clinical testing [e.g. extracts of tomato (Solanum lycopersicum), herbs from the Genus Salvia, cocoa (Theobroma), tea (Camellia sinensisor) and coffee (Coffea Arabica). This review will discuss clinically tested cognitive enhancers derived from edible crop species and discuss their use alongside other classes of nootropics.

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Anaemia is a major cause of morbidity and mortality among people living with human immunodeficiency virus (HIV) infection. While adherence to antiretroviral treatment (ART) reduces the incidence of anaemia, non-adherence (defaulting) to ART is associated with a number of haematologic derangements including anaemia. However, the mechanisms and predictors of anaemia have not been examined among ART defaulters in western Kenya. This study, therefore, aimed at evaluating the anaemia prevalence and classification of the anaemia based on haemoglobin (Hb) concentrations and erythrocyte morphology as well as suppression of erythropoiesis in ART-defaulting adults at a comprehensive care clinic in western Kenya.

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Chlorpyrifos is a hazardous organophosphate pesticide used worldwide thus its biodegradation is need of the time. In the present study 13 bacterial strains were isolated from collected soil samples of different agro climatic regions and out of them one bacterial strain was screened out as potent degrader of Chlorpyrifos on the basis of percentage degradation using high pressure liquid chromatography (HPLC).

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