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Articles Related to Mechanism

Combating Childhood Obesity with an Integrated School Curriculum

The prevalence of overweight and obesity among US adults is well-documented and lifestyle intervention remains the foundation for all overweight and obesity treatment interventions, even when bariatric surgery is offered. Unfortunately, lifestyle intervention, though clearly a vital part of any obesity treatment, including bariatric surgery, has not been found to be as effective in achieving health benefits as hoped for.
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Orally Disintegrating Tablets: A Short Review

This article summarizes the advantages of orally disintegrating tablets (ODTs) as well as critical issues during evaluation of ODTs such as bioequivalence and challenges and limitations of ODTs and finally present and the future of ODTs. ODTs have received everincreasing demand and the field has become a rapidly growing area in the pharmaceutical industry.
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Molecular Mechanism Linking BRCA1 Dysfunction to High Grade Serous Epithelial Ovarian Cancers with Peritoneal Permeability and Ascites

Ovarian cancer constitutes the second most common gynecological cancer with a five-year survival rate of 40%. Among the various histotypes associated with hereditary ovarian cancer, high-grade serous epithelial ovarian carcinoma (HGSEOC) is the most predominant and women with inherited mutations in BRCA1 have a lifetime risk of 40-60%. HGSEOC is a challenge for clinical oncologists, due to late presentation of patient, diagnosis and high rate of relapse. Ovarian tumors have a wide range of clinical presentations including development of ascites as a result of deregulated endothelial function thereby causing increased vascular permeability of peritoneal vessels.
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Case Studies of 17 Patients

This retrospective review of 17 patients suggests an increased risk of adverse events including premature death with opiate discontinuation long after withdrawal stage. The results are consistent with previously reported yet not fully understood – opiate associated neuro protective mechanism – against premature death for some vulnerable subgroups.
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Examination of Some Country made Smooth Bore Firearms

Present trend of the crimes in India reveals that a wide variety of firearms including factory /country made are illegally used in crimes like murder, armed robbery, riot, poaching etc. Out of the total firearms received in Tripura State Forensic Science Laboratory, Agartala for the last ten years, about 30% of the firearms are observed to be belonging to country made pistol/pipe guns.
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Molecular Mechanisms of Mismatch Repair Genes in Cancer – A Brief Review

The DNA mismatch repair (MMR) system is necessary for the maintenance of genomic stability. The MMR system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops (IDLs) and heterologies generated during DNA replication and recombination.
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Salmonella Serovars and Their Host Specificity

Salmonella is a causative agent for a wide variety of pathological diseases in humans, cattle, poultry and other farm animals and hence Salmonella infections are a major cause of concern to humans, veterinary animals and to food industry.
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Editorial Board Members Related to Mechanism

Gyorgy Nagy

Associate Professor
Faculty of Medicine
Semmelweis University
Hungary

Naim Deniz Ayaz

Professor
Department of Food Hygiene & Technology
Kirikkale University
Turkey

GEORGE DINOS

Associate Professor
Department of Biochemistry
University of Patras
Greece

Lihua Song

Associate Professor
Chief, Laboratory of Rickettsiology
Beijing Institute of Microbiology and Epidemiology
China

Mridula Chopra

Senior Lecturer
School of Pharmacy and Biomedical Sciences
University of Portsmouth
United Kingdom

ALBA A. TRESPALACIOS

Professor
Department of Microbiology
Pontificia Universidad Javeriana
Colombia

Zubair M Ahmed

Associate Professor
Department of Otorhinolaryngology Head & Neck Surgery
School of Medicine
University of Maryland
United States

Desheng Pei

Professor
Chongqing Institute of Green and Intelligent Technology
Chinese Academy of Sciences
China

Jason J. Guo

Associate Professor
Center for Drug Discovery
Northeastern University
United States

Elena Kolomietz

Assistant Professor
Department of Pathology and Lab Medicine
University of Toronto
Canada
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