Articles Related to asthma
Study to Find Clinical Characteristics of ABPA in Patients of Severe Bronchial Asthma and Its Relation with Serum Ige Level at Teriary Care Center North India
Allergic bronchopulmonary aspergillosis (ABPA) is an idiopathic inflammatory disease of the lung, characterized by an allergic inflammatory response to colonization of the airways by Aspergillus fumigatus or other fungi. Untreated
or inadequatetreatment may lead to poor outcome in patients. Raised level of serum IgE of more than 1000 IU/ML have
been considered as one if theimportant diagnostic criteria for ABPA, however relation of serum IgE withs severity ofdiseases is lacking. This study was conducted to find out level of serum IgE in patients ofABPA and to find out corelation of
Serum IgE with duration of symptoms and diseasesseverity.
Citrus Jabara Juice Diminishes Allergic Airway Inflammation in an Ovalbumin (OVA)-Induced Murine Asthma Model
Citrus jabara is a type of citrus fruit originally grown in Kitayama-Mura in Wakayama, Japan, and is reputed to have anti-allergic properties. In this study, we tested whether citrus jabara juice inhibits inflammatory mediators in a mouse allergic asthma model.
Clinical Features and Management of Eosinophilic Asthma
Asthma is a common chronic airway disease affecting about 334 million people worldwide, and an estimated 7 million children
globally. Approximately 10% of patients with asthma have severe refractory disease, which is uncontrolled despite using high doses
of inhaled corticosteroids and other modifiers. Among these patients are patients with eosinophilic asthma. Eosinophilic asthma is a
phenotype of asthma that is usually very severe and persistent, with frequent exacerbations. It is characterized by the presence of high
levels of eosinophils, and CD+4 Th2 cells in the lungs and airways. Eosinophils play a pivotal role in the pathogenesis and severity
of asthma. Most patients with eosinophilic asthma respond to the classic stepwise guided treatment. However, 50% of patients with
eosinophilic asthma are refractory to corticosteroids and long-acting β2-agonists. Currently, there are targeted personalized biologics
for these patients. These biotherapeutics include IgE, interleukin and interleukin receptor monoclonal antibodies,they have added
advantageous steroid-sparing effects.
Discovery of Potent Drug Candidates of Adhatoda vasica Against Target Proteins IL- 4 and IL- 13 of Asthma – An in Silico
Bronchial-Asthma, Adhatoda-vasica, In-Silico, IL- 13, IL- 4
Oral Health in Asthmatics: A Review
Asthma is a chronic inflammation of airway tract characterized by airway obstruction and hyper responsiveness presenting with symptoms of wheezing, coughing, chest tightness and dyspnoea. It is a serious health issue with the worldwide occurrence. Antiasthmatic drugs have unfavorable effects on oral health causing dental caries, xerostomia, dental erosion, periodontal disease and orofacial deformities. This review concludes that asthma drastically affects oral health but preventive measures can help to improve
quality of life.
Effects of Transfer Point Glucan #300 Supplementation on Children exposed to Passive Smoking - Placebo-driven Double-blind Clinical Trials
In this study, we focused on the effect of β-glucan supplementation of children with chronic respiratory problems. We measured the
levels of cortisol, salivary IgE and cotinine in 56 children and evaluated the effect of 30 day supplementation with 100 mg/day oral
dose of yeast-derived β-glucan. Our results showed strong decrease of cotinine and cortisol levels in saliva of β-glucan-supplemented
children.
Reduction of Bitterness and Enhancing Palatability of Cetirizine Oral Liquid Dosage Forms by Cyclodextrins
The aim of this manuscript is to study cyclodextrins (CDs) as a potential excipient to suppress bitterness and enhance palatability of pediatric liquid preparations for Cetirizine, an extremely bitter drug. Natural α, β and γ CDs; and β CD derivatives such as hydroxyl propyl (HP), randomly methylated (RM) and sulfobutyl ether (SBE) β-CDs were screened in different molar ratios of 1:1, 1:2 and 1:3 for their inhibition of the extremely bitter taste of Cetirizine using the human gustatory sensation test.
Editorial Board Members Related to asthma
Grant Dewson
Laboratory Head
Cell Signalling and Cell Death Division
Walter & Eliza Hall Institute of Medical Research
Australia
Cell Signalling and Cell Death Division
Walter & Eliza Hall Institute of Medical Research
Australia
VICTORIA J VIEIRA-POTTER
Assistant Professor
Department of Nutrition and Exercise Physiology
University of Missouri
United States
Department of Nutrition and Exercise Physiology
University of Missouri
United States
Muhammad Nasir Afzal
Professor & Director
Department of physiology
College of Medicine, Alfaisal University
Saudi Arabia
Department of physiology
College of Medicine, Alfaisal University
Saudi Arabia