Articles Related to biology
Review on MALDI TOF MS: Modern Disease Diagnosis Approaches in Microbiology and its Mechanism
Matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) has become a widely used technique for the rapid, accurate, durable, economical, and trustworthy method for identification of bacteria, mycobacteria and fungal pathogens in the microbiology laboratory.
Former Effective Immunotherapy without Adverse Events of Inoperable Epithelial Ovarian Cancers and a Prospect for the Immune Prophylaxis
Current cancer treatments by immune checkpoint blockades are limited due to severe adverse events caused by alteration of the immune system required for homeostasis of normal tissues. Common cancer chemotherapy alters the quality of patients’ lives. Platinum-based treatment can lead to severe neurotoxicity with chronic debilitation. Additionally, survival of patients with epithelial ovarian cancers (EOCs) has remained poor despite extensive cytoreductive surgery, high dose chemotherapy, checkpoint blockades and immunotherapies effective in some other types of cancer. The pathobiology of EOC cancer stem cells (CSCs) is not well understood. Observations demonstrate that EOCs exhibit in vivo two distinct CSC types - perivascular diploid CSCs dividing asymmetrically with the help of the host suicidal CD8+ T cells, and haploid CSCs at the cancer abdominal surface originating from meiosis I cytokinesis of bulk surface cancer cells. The perivascular CSCs contribute to the cancer cell bulk and, via left ovary venous blood, can cause EOC liver metastases. Haploid CSCs released from the bulk cancer surface cause the common pelvic and abdominal EOC spread. Former elimination of the host antibodies blocking T cell effectors by intermittent doses of cyclophosphamide exhibiting significant immunomodulatory anticancer effects, facilitation of the immune system reactivity against alloantigens of cancer cells by blood transfusions, and augmentation of anticancer immunity by bacterial toxins, resulted during the subsequent treatment-free period into rejection of inoperable EOCs without any adverse events during the treatnment. To help prevent cancer relapses, patients treated for advanced primary epithelial cancers should be considered as candidates for continuously stimulating immune anticancer activity by treatments such as daily metformin and weekly lentinan consumptions.
Serum Haptoglobin Responses following Rumenotomy in the Sahel Goat
Fifteen Sahel goats were randomly allocated into three groups A, B and C to evaluate Serum Haptoglobin (Hp) profiles following rumenotomy as markers of surgical stress using Quantitative ELISA.
Some Basic Differential Models in Mathematical Biology
It is widely known that many problems in the mathematical biology can be modeled by the differential equations, and the corresponding
systems are usually called as biological dynamic systems.
A Protocol for the Determination of the Growth Rate of Organisms Subject to Interrupted Exponential Growth
A standard laboratory procedure with cultures that grow exponentially involves regular dilution (so that the organism is never nutrient limited). When the logarithm of growth is plotted against time, exponential growth then appears as a series of parallel lines.
Modeling of Gene Regulatory Networks: A Literature Review
In the last years numerous methods have been developed and applied to reconstruct the structure and dynamic rules of gene-regulatory networks from different high-throughput data sources such as gene expression data.
Networks: Elucidating Experimental Data by Differential Protein-Protein Interactions
Recently, the pathogenesis of coronary atherosclerosis - a primary cause of cardiovascular disease – studied in a swine model has been investigated by considering in particular the effects of a high cholesterol diet lasting 8 or 16 weeks.
Procalcitonin versus C-Reactive Protein in Neonatal Sepsis
Urinary tract infection (UTI) is the most common serious bacterial infection in febrile children younger than 3 months, with reported rates ranging from 5% to 20% depending on different series. Neonates and infants up to age 2 months who have pyelonephritis usually do not have symptoms localized to the urinary tract.
Case Series of Pneumococcal Meningitis in the Post 13-valent Pneumococcal Conjugate Vaccine Era
Streptococcus pneumoniae is a leading cause of meningitis. Although rates of bacterial meningitis have decreased after pneumococcal
conjugate vaccine introduction, pneumococcal meningitis has not been eliminated. In this case series, we describe the presentation,
serotypes, and outcomes of 11 children with pneumococcal meningitis at a tertiary children’s hospital after the 13-valent pneumococcal
conjugate vaccine (PCV13) was introduced, from 2011-2013. The median age of children with meningitis was 7 years. The majority
of the isolates (82%) were susceptible to penicillin. Most isolates (73%) were serotyped and there was no evidence of disease caused
by serotypes contained in PCV7
Salmonella Serovars and Their Host Specificity
Salmonella is a causative agent for a wide variety of pathological diseases in humans, cattle, poultry and other farm animals and hence Salmonella infections are a major cause of concern to humans, veterinary animals and to food industry.
Adults Mammary Stem Cell in Cow’s Milk: New Perspectives and Future Challenge
The discovery of the presence of stem cells and precursors with high regenerative potential in the mammary gland, hypothetically maintained throughout the course of the productive life of the dairy cow sheds an interesting perspective in the research which is interested to clarify all physiological clues and possible solutions to increase or maintain longer the potential production of dairy cows during life span of lactation.
MAPK Pathway in Skeletal Muscle Diseases
Mitogen-Activated Protein Kinase (MAPK) pathway is a signal transduction pathway that functions in a wide range of physiological and pathophysiological cellular events including cell proliferation, differentiation, apoptosis, migration, inflammation, metabolic disorders and diseases.
The End of the Golden Age of Antibiotics?
The discovery of a substance with antibacterial properties was expected to permanently diminish the occurrence of bacterial infections posing a threat to health and life. Since the discovery of penicillin many new groups of antibiotics have been introduced into treatment of disease in people and animals, but their excessive and frequently unjustified use, and most importantly, incorrect dosage, have led to numerous unanticipated problems in contemporary human and veterinary medicine.
Editorial Board Members Related to biology
Solomon Ike Okosun
Associate Professor
Department of Population Health Sciences
School of Public Health
Georgia State University
USA
Department of Population Health Sciences
School of Public Health
Georgia State University
USA
AMY H. TANG
Associate Professor
Department of Microbiology and Molecular Cell Biology
Eastern Virginia Medical School
United States
Department of Microbiology and Molecular Cell Biology
Eastern Virginia Medical School
United States
Charles J. Malemud
Professor
Department of Medicine and Anatomy
Case Western Reserve University
United States
Department of Medicine and Anatomy
Case Western Reserve University
United States
Daniela Iannazzo
University Researcher
Department of Electronic Engineering, Industrial Chemistry and Engineering
University of Messina
Italy
Department of Electronic Engineering, Industrial Chemistry and Engineering
University of Messina
Italy
Yavuz Selim Cakmak
Associate Professor
Director of Vocational School of Health Services
Aksaray University
Turkey
Director of Vocational School of Health Services
Aksaray University
Turkey