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Scalp, Skull, Lung and Bone Metastasis from Follicular Thyroid Carcinoma - A Rare Case Report

Concurrent scalp, skull, lung and bone metastasis from follicular thyroid carcinoma is a very rare event. We herein present the case of a 37- year’s old lady, who presented to us with huge scalp swelling that proved to be metastasis from a follicular thyroid carcinoma. The metastatic workup disclosed bilateral lung metastasis and additional metastasis in right iliac crest and 6th rib. The course of her disease was relentless. Although follicular thyroid carcinoma has an excellent prognosis, the presence of metastatic disease leads to a very dismal prognosis.
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Antrochoanal Polyp Harboring Cholesterol Granuloma: A Case Study

Cholesterol granuloma (CG) is a foreign body reaction to the deposition and inadequate drainage of cholesterol crystals that are frequently found in association with chronic diseases. The clinical symptoms are non-specific. The differential diagnosis of CG includes cysts, mucocoeles and neoplasms. Radiological and histopathological findings are essential for diagnosis of CG. In this report it is aimed to introduce a case of CG in antrochoanal polyp with its clinical and histopathological findings.
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Infantile Acute Generalized Pustular Psoriasis: A Case Report

Generalized pustular psoriasis (GPP) is an acute and uncommon form of psoriasis, representing about 3% of all psoriasis cases. Triggers may include streptococcical infections, emotional stress, vaccinations and exposure to medications such as penicillin. Systemic therapy is often necessary for GPP, since it may rapidly evolve, leading to significant and potentially fatal complications. Here, we describe the case of a 5-year-old male presenting with diffuse erythema, confluent scaly plaques and painful pustules localized on the trunk and limbs. Systemic manifestations such as fever, general lymphadenopathy and arthritis were also observed. To date, no standardized treatment guideline exists for infantile acute generalized pustular psoriasis. Our patient responded successfully to cyclosporine treatment within 4 weeks without any side effects. Thus, cyclosporine could be considered a useful agent in cases of pediatric GPP, keeping in mind its side effect profile in child population.
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Development of Acute Implant Peri-Implantitis After Immediate Implant Loading: A Case Report

implantitisIntroductionThe acute apical peri-implantitis (AAPI) is defined as a clinically symptomatic periapical lesion that develops shortly after implant insertion while the coronal portion of the implant substains a normal bone-to-implant interface. The etiology of AAPI is unclear. Regardless of etiology, the management of AAPI has been attempted by either respective or regenerative techniques.
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Mucinous Adenocarcinoma of the appendix with Retroperitoneal and Pelvic Bone Extension - A Case Report and Literature Review

The Appendiceal mucocele (AM) was considered as a rare dilation of the appendiceal lumen. Four different types of AMs are defined according to the cause of obstruction, for both benign and malignant, including retention cysts, epithelial hyperplasia, mucinous cystadenoma, and mucinous cystadenocarcinoma.
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Two Novel Cases of Marfan Syndrome with FBN1 whole Gene Deletion: Laboratory Assay and Cases Review

Background: Marfan syndrome is a hereditary disorder of connective tissue mainly characterized by abnormalities in the cardiovascular, skeletal and ocular systems. It is most frequently due to heterozygous point mutations in the FBN1 gene located on chromosome 15q21.1 and coding for fibrillin-1 protein. Over 3000 FBN1 mutations have been reported in the FBN1 Universal Mutation Database, among these FBN1 large rearrangements account for <2%. Several studies have shown that 15q deletions encompassing the whole FBN1 gene are associated with Marfan syndrome and FBN1 haploinsufficiency is involved in the pathogenesis of the disease. Since now 19 cases of FBN1 entire deletion have been already described.
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A Case of Bilateral Duplicated Ureter - Gross Anatomy

Duplicated ureter is a frequent malformation that occurs in approximately 1 in 20 people. We herein report the detailed case of bilateral duplicated ureter in which two ureters originated from a single renal pelvis and merged just proximal to the ureterovesical junction.
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Role of Vaginal Washing in Semen Detection and D.N.A. Profiling in Delayed Medical Examination of Sexual Assault Cases: A Case Study

Sexual assault is a social problem faced by every society irrespective of caste, creed or culture. In cases of sexual assault, as soon as the victim files the First Information Report (F.I.R.) she gets the medical examination at nearby government hospital by a gynecologist. But it is seen that due to hesitation, social problems or any kind of relation between the victim and the accused matter is not reported immediately to the police. This hesitation results in the delay of the medical examination and collection of samples like vaginal swabs, breast swabs, nails swab, and other bodily swabs. In such cases, it is noted that the detection of semen and profiling of DNA fails due to daily hygienic chores. In this delayed medical examination case, semen detection and D.N.A.
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Individual Implants-Retained Maxillary and Mandibular Overdentures with Limited Vertical and Horizontal Space: A Clinical Case Report

Many clinical cases and literature review have revealed the implant-retained-overdentures (IROs) treatment success and predictability in elderly patients. According to the previous studies IROs treatment in maxillary arch prefer implants connected by a bar, while in mandibular arch the first option is to use un-splinted implants when 2 implants have been inserted. The aim of this clinical case report is to present prosthetic rehabilitation of both maxillary/mandibular arches with IROs. In this report four individual implants retained maxillary overdenture, and two individual implants retained mandibular overdenture were fabricated, due to the lack of sufficient vertical crown height space (CHS) and horizontal space. The patient was followed-up for more than 24 months with no complications.
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Macrocystis of the Lung in a Preterm Neonate: Case Report

Thoracic ultrasonography has been used to evaluate pulmonary parenchyma and the macrocystis of the lung in a preterm with congenital cystic adenomatoid malformation type I. The images gained have been important for diagnosis and therapeutic strategies in our case. An infant was prematurely born with congenital cystic adenomatoid malformation type I. The chest X-ray and computerized tomography showed a great opaque area in the entire right lung, we considered performing a pneumonectomy. This opaque area hampered the expansion of left lung. After draining the macrocystis by ultrasonography-guided puncture, it was possible considering and performing the lobectomy due to the reduction of the volume of macrocystis. During follow up at 4 months, the infant did not show complications and the chest X-ray revealed the reduction of volume of the dense area in parenchyma of right lung.
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Double Stroke and Double Malignancy: A Case Report

Stroke associated with malignancy is rapidly increasing. Lesion types mainly resemble cardio embolic multiple ischemic lesions. We present a rare stroke patient with both ischemic and hemorrhagic lesions simultaneously. The etiology of stroke was found to be due to lung cancer and essential thrombocytosis. Differential diagnosis in this case can help for further investigation of strokes with malignancy.
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Familial Hypokalemic Periodic Paralysis with Myotonic Phenomenon : Case Report

Hypokalemic Periodic Paralysis (HypoPP) is a rare disease whereby voltage-gated ion channels are mutated and it is characterized by episodic flaccid paralysis concomitant to variations in blood potassium levels. Attacks usually happen after exercise or high carbohydrate meals. The diagnosis is made with laboratory data which helps to exclude other causes and confirm low serum potassium or myotonia on eletromyography (EMG).
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Bullous Lichen Planus: A Case Report with Review of Literature

Oral lichen planus is a chronic inflammatory mucocutaneous disease which frequently involves the oral mucosa. A 48-year-old male patient with the chief complaint of burning sensation in bilateral buccal mucosa, upper and lower labial mucosa diagnosed as Bullous lichen planus and treated with systemic prednisolone and Benzydamine oral rinse. Patient was followed for 6 months and was almost free of lesions. The case is reported with review of current modalities in the management of oral lichen planus.
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Atypical Granulomatous Lesion of Gingiva: A Case Report on Rare Manifestation of Tuberculosis in Oral Cavity

Primary tuberculosis lesion in oral cavity is a rare clinical entity. We report a case of gingival tuberculosis manifested as chronic ulceration with pus discharge.
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Primary Osteosarcoma of the Nasal Fossa: An Exceptional Presentation

Sarcomas of the head and neck are very rare accounting for approximately 1% of all head and neck neoplasms. Primary osteosarcomas of the nasal cavity are less than 0.5% of the osteosarcomas occur in this location. Because of the rarity of this presentation, we report a case of a 54 year old male with primary osteosarcoma arising de novo from the nasal cavity, presented with left epistaxis and bilateral nasal obstruction.
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Editorial Board Members Related to case

Guo-Fang Zhang

Assistant Professor
Department of Nutrition
Case Western Reserve University
United States

NIKOLAS P. LEMOS

Professor
Pathology & Laboratory Medicine
University of California
United States

Ana Cristina Lindsay

Associate Professor
Department of Nutrition
University of Massachusetts Boston
United States

Norio Yasui-Furukori

Associate Professor
Department of Neuropsychiatry
Hirosaki University School of Medicine
Japan

RICHARD ROBESON

Adjunct Professor of Practice - Bioethics
Dept. of Communication Bioethics Faculty
Wake Forest University
USA

PATRICIA A. KRUK

Professor
Department of Obstetrics and Gynecology
USF Morsani College of Medicine
University of South Florida
United States

Wen-Quan Zou

Associate Professor
Departments of Pathology and Neurology
Case Western Reserve University School of Medicine
United States

Jack Ho WONG

Research Associate
School of Biomedical Sciences
Faculty of Medicine
The Chinese University of Hong Kong
Hong Kong

Lufang Zhou

Lufang Zhou
Assistant Professor
The University of Alabama
Birmingham
United Kingdom

Charles J. Malemud

Professor
Department of Medicine and Anatomy
Case Western Reserve University
United States
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